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1.发明申请Dopamine Neuron Stimulating Peptide-11 Protection From Complex 1 Mitochondrial Inhibitors 有权多巴胺神经元刺激肽-11保护从复杂1线粒体抑制剂公开(公告)号：US20130065830A1
公开(公告)日：2013-03-14
申请号：US13586617
申请日：2012-08-15
CPC分类号： A61K38/08 , A61K38/10 , A61K38/185
摘要： The present invention relates to the use of novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), for treating brain diseases and injuries that result in dopaminergic deficiencies and mitochodrial dysfunction, e.g., reduced complex I enzyme activity.
摘要翻译： 本发明涉及新型蛋白质的用途，本文称为酰胺化神经胶质细胞系衍生的神经营养因子（GDNF）肽（或酰胺多巴胺神经元刺激肽（ADNS肽）），用于治疗导致多巴胺能的脑部疾病和损伤 缺陷和丝裂素功能障碍，例如复合物I酶活性降低。
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2.发明授权Amidated dopamine neuron stimulating peptide restoration of mitochondrial activity 有权酰胺多巴胺神经元刺激肽恢复线粒体活性公开(公告)号：US09402875B2
公开(公告)日：2016-08-02
申请号：US13586617
申请日：2012-08-15
CPC分类号： A61K38/08 , A61K38/10 , A61K38/185
摘要： The present invention relates to the use of novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), for treating brain diseases and injuries that result in dopaminergic deficiencies and mitochodrial dysfunction, e.g., reduced complex I enzyme activity.
摘要翻译： 本发明涉及新型蛋白质的用途，本文称为酰胺化神经胶质细胞系衍生的神经营养因子（GDNF）肽（或“酰胺化多巴胺神经元刺激肽（ADNS肽）”），用于治疗导致的脑部疾病和损伤 多巴胺能缺陷和丝裂素功能障碍，例如复合物I酶活性降低。
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3.发明申请Amidated Dopamine Neuron Stimulating Peptides for CNS Dopaminergic Upregulation 审中-公开酰胺多巴胺神经元刺激肽用于CNS多巴胺能上调公开(公告)号：US20110178025A1
公开(公告)日：2011-07-21
申请号：US12646511
申请日：2009-12-23
申请人： Luke H. Bradley , Don M. Gash , Greg A. Gerhardt , John D. Glass
发明人： Luke H. Bradley , Don M. Gash , Greg A. Gerhardt , John D. Glass
摘要： The present invention relates to novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), that are useful for treating brain diseases and injuries that result in dopaminergic deficiencies.
摘要翻译： 本发明涉及新型蛋白质，本文称为酰胺化胶质细胞系衍生的神经营养因子（GDNF）肽（或“酰胺化多巴胺神经元刺激肽（ADNS肽）”），其可用于治疗导致的脑部疾病和损伤 在多巴胺能缺陷。
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4.发明申请AMIDATED DOPAMINE NEURON STIMULATING PEPTIDES FOR CNS DOPAMINERGIC UPREGULATION 审中-公开用于中枢神经系统多胺拮抗剂的氨基多巴胺神经元刺激肽公开(公告)号：US20100035820A1
公开(公告)日：2010-02-11
申请号：US12508916
申请日：2009-07-24
申请人： Luke H. Bradley , Greg A. Gerhardt , Don M. Gash , John D. Glass
发明人： Luke H. Bradley , Greg A. Gerhardt , Don M. Gash , John D. Glass
摘要： The present invention relates to novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), that are useful for treating brain diseases and injuries that result in dopaminergic deficiencies.
摘要翻译： 本发明涉及新型蛋白质，本文称为酰胺化胶质细胞系衍生的神经营养因子（GDNF）肽（或“酰胺化多巴胺神经元刺激肽（ADNS肽）”），其可用于治疗导致的脑部疾病和损伤 在多巴胺能缺陷。
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