公开(公告)号：US10983031B2

公开(公告)日：2021-04-20

申请号：US16653662

申请日：2019-10-15

Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  MBD KOREA, CO., LTD.

Inventor： Hyo Jeong Kuh ,  Ji Hoon Kang ,  Dong Wo Lee

IPC: G01N1/04 ,  C12M1/12 ,  C12M1/34

Abstract: A method for producing a sample slice includes providing a disk, providing a jig on the disk for supporting side portions of a material, providing the material inside the jig, providing a pillar assembly on the jig, the pillar assembly that includes a first base member having a plurality of through holes, a second base member detachably mounted to said first base member, and a plurality of pillars supported between said first and second base members and arranged to be exposed through the plurality of holes, inserting the plurality of pillars into the material, solidifying the material, separating the jig and the pillar assembly to remove the material from the jig, and cutting a sample slice from the material with a cutter.

公开(公告)号：US11331672B2

公开(公告)日：2022-05-17

申请号：US16085873

申请日：2018-01-30

Applicant: MBD KOREA. CO., LTD.

Inventor： Bo Sung Ku ,  Dong Woo Lee

IPC: B01L3/00

Abstract: The present invention relates to a pillar structure for a biochip, the pillar structure including: a substrate portion which has a plate-shaped structure; multiple pillar portions which protrude from one surface of the substrate portion and each of which has an end portion on which a sample is disposed; and smooth surface forming portions which are formed on the other surface of the substrate portion that defines the plate-shaped structure together with the one surface of the substrate portion, the smooth surface forming portions forming smooth surfaces each having a relatively concave groove shape at a portion corresponding to a circumferential surface of each of the pillar portions.

公开(公告)号：US20200376484A1

公开(公告)日：2020-12-03

申请号：US16085873

申请日：2018-01-30

Applicant: MBD KOREA. CO., LTD.

Inventor： Bo Sung KU ,  Dong Woo LEE

IPC: B01L3/00

Abstract: The present invention relates to a pillar structure for a biochip, the pillar structure including: a substrate portion which has a plate-shaped structure; multiple pillar portions which protrude from one surface of the substrate portion and each of which has an end portion on which a sample is disposed; and smooth surface forming portions which are formed on the other surface of the substrate portion that defines the plate-shaped structure together with the one surface of the substrate portion, the smooth surface forming portions forming smooth surfaces each having a relatively concave groove shape at a portion corresponding to a circumferential surface of each of the pillar portions.

公开(公告)号：US20200041386A1

公开(公告)日：2020-02-06

申请号：US16653662

申请日：2019-10-15

Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  MBD KOREA, CO., LTD.

Inventor： Hyo Jeong KUH ,  Ji Hoon KANG ,  Dong Wo LEE

IPC: G01N1/04 ,  C12M1/12 ,  C12M1/34

Abstract: A method for producing a sample slice includes providing a disk, providing a jig on the disk for supporting side portions of a material, providing the material inside the jig, providing a pillar assembly on the jig, the pillar assembly that includes a first base member having a plurality of through holes, a second base member detachably mounted to said first base member, and a plurality of pillars supported between said first and second base members and arranged to be exposed through the plurality of holes, inserting the plurality of pillars into the material, solidifying the material, separating the jig and the pillar assembly to remove the material from the jig, and cutting a sample slice from the material with a cutter.

公开(公告)号：US20190039064A1

公开(公告)日：2019-02-07

申请号：US16075500

申请日：2017-08-09

Applicant: MBD KOREA. CO., LTD. ,  MEDICINAL BIOCONVERGENCE RESEARCH CENTER

Inventor： Dong Woo LEE ,  Chan Ho PARK ,  Sung Hoon KIM

IPC: B01L3/00

Abstract: Provided is a bio chip structure for a comparative experiment. The bio chip structure for a comparative experiment according to the present invention may include: a first pillar substrate including at least one first pillar where a first sample is disposed; a second pillar substrate including at least one second pillar where a second sample is disposed; and a well substrate including wells to which at least one pair of the first pillars of the first pillar substrate and the second pillar of the second pillar substrate is inserted. Accordingly, a comparative experiment to culture a different kind of samples may be conducted in an identical environment, a different kind of samples, which are the subjects of a comparative experiment, may be rapidly and accurately disposed on a plurality of pillars, and an experimental group or a control group may be easily replaced.

公开(公告)号：US20170261407A1

公开(公告)日：2017-09-14

申请号：US15347767

申请日：2016-11-09

Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  MBD KOREA, CO., LTD.

Inventor： Hyo Jeong KUH ,  Ji Hoon KANG ,  Dong Wo LEE

IPC: G01N1/04 ,  C12M1/34 ,  C12M1/12

CPC classification number: G01N1/04 ,  C12M25/14 ,  C12M41/12 ,  G01N1/06 ,  G01N1/36 ,  G01N2001/366

Abstract: The present invention relates to a pillar assembly and an apparatus for producing a sample block comprising the same, and according to one aspect of the present invention, it is possible to change arrangement of pillars, and sample slices can be easily obtained from the sample block.