公开(公告)号：US20030116707A1

公开(公告)日：2003-06-26

申请号：US10223401

申请日：2002-08-19

申请人： Micromass Limited

发明人： Jeff Brown ,  Dominic Gostick ,  Edouard S. P. Bouvier ,  John Charles Gebler ,  Peter Jeng Jong Lee ,  James Ian Langridge ,  Emmanuelle Claude ,  Weibin Chen

IPC分类号： H01J049/04

CPC分类号： H01J49/0418 ,  B01L3/5088

摘要： A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.

摘要翻译： 公开了一种MALDI样品板1，其包括具有圆形槽或护城河3的金属基板2.将疏水性聚四氟乙烯层4施加到基板2上，并且激光蚀刻基板2的中心部分5，其粗糙化表面 然后将薄聚苯乙烯层施加到聚四氟乙烯层4和中心部分5。

公开(公告)号：US20010010354A1

公开(公告)日：2001-08-02

申请号：US09805062

申请日：2001-03-14

申请人： MICROMASS LIMITED

发明人： James Speakman ,  Raymond Clive Haines ,  Patrick James Turner ,  Thomas Oliver Merren ,  Stuart Alan Jarvis

IPC分类号： H01J049/00

CPC分类号： H01J49/063 ,  H01J49/0481 ,  H01J49/105

摘要： A plasma mass spectrometer comprises a plasma torch (1) for generating ions from a sample introduced into a plasma (2), a nozzle-skimmer interface (3, 5) for transmitting said ions into a first evacuated chamber (11), ion guiding means (12), an apertured diaphragm (18) dividing said first evacuated chamber (11) from a second evacuated chamber, and an ion mass-to-charge ratio analyzer in the second chamber for producing a mass spectrum. The ion guiding means comprises a multipole rod-set (13, 14, 15), means for applying an AC voltage between rods in the set, and means (22) for introducing into said ion guiding means an inert gas selected from the group comprising helium, neon, argon, krypton, xenon and nitrogen so that the partial pressure of said inert gas inside said rod-set is at least 10null3 torr. Interfering peaks in the spectrum, such as ARnull, are thereby reduced

摘要翻译： 等离子体质谱仪包括用于从引入等离子体（2）中的样品产生离子的等离子体焰炬（1），用于将所述离子传输到第一真空室（11）中的喷嘴 - 撇渣器界面（3,5），离子导向 装置（12），在第二室中将所述第一抽真空室（11）与第二抽空室分开的有孔隔膜（18）和离子质荷比分析器产生质谱。 离子引导装置包括多极杆组（13,14,15），用于在组中的杆之间施加AC电压的装置，以及用于将所述离子引导装置引入惰性气体的装置（22），所述惰性气体选自包括 氦气，氖气，氩气，氪气，氙气和氮气，使得所述棒组件内的所述惰性气体的分压至少为10 -3乇。 从而降低光谱中的干扰峰，如AR +

公开(公告)号：US20170047212A1

公开(公告)日：2017-02-16

申请号：US15305684

申请日：2015-04-24

申请人： MICROMASS LIMITED UK

发明人： Daniel James KENNY

IPC分类号： H01J49/00 ,  H01J49/42

CPC分类号： H01J49/0081 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/0045 ,  H01J49/4215

摘要： A method of mass spectrometry is disclosed comprising passing ions through a first stage and a second stage of a mass spectrometer and monitoring a first ion acquisition for a first dwell time extending from a time T1 to a time T1+Tdwell1. The method further comprises reconfiguring the mass spectrometer or one or more components of the mass spectrometer to monitor a second ion acquisition and setting the first stage to transmit ions of the second ion acquisition at a time T, wherein T T1+Tdwell1 and determining the time T based on a known or calculated ion transit time through one or more regions or components of the mass spectrometer disposed downstream of the first stage

摘要翻译： 公开了一种质谱法，其包括使离子通过质谱仪的第一阶段和第二阶段，并监测从时间T1延伸到时间T1 + Tdwell1的第一停留时间的第一离子获取。 该方法还包括重新配置质谱仪或质谱仪的一个或多个组件以监测第二离子获取并设置第一阶段以在时间T传递第二离子获取的离子，其中T T1 + Tdwell1并且基于通过质量的一个或多个区域或部分的已知或计算的离子渡越时间来确定时间T 光谱仪布置在第一阶段的下游