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    PROSTHETIC VALVE WITH LEAFLET CONNECTORS
    1.
    发明申请
    PROSTHETIC VALVE WITH LEAFLET CONNECTORS 审中-公开

    公开(公告)号：US20180280136A1

    公开(公告)日：2018-10-04

    申请号：US15995597

    申请日：2018-06-01

    申请人： MITRALTECH LTD.

    发明人： Ilia HARITON ,  Boaz HARARI ,  Meni IAMBERGER ,  Aviram BAUM

    IPC分类号： A61F2/24 ,  B23P15/00

    摘要： A unitary flexible sheet is folded to define: (i) a panel, defining a plane, and having a first side facing in a first direction away from the plane, (ii) a first tab, disposed on the first side of the panel, and protruding in the first direction away from the panel, and (iii) a second tab, disposed on the first side of the panel, and protruding in the first direction away from the panel. Between the first tab and the second tab are secured (i) a first-leaflet commissural portion of a first prosthetic leaflet, and (ii) a second-leaflet commissural portion of a second prosthetic leaflet. At the first tab, the sheet is folded to define a first cushion at a downstream edge of the first tab. At the second tab, the sheet is folded to define a second cushion at a downstream edge of the second tab.

    PROSTHETIC VALVE WITH LEAFLET CONNECTORS
    3.
    发明申请
    PROSTHETIC VALVE WITH LEAFLET CONNECTORS 有权

    公开(公告)号：US20180153687A1

    公开(公告)日：2018-06-07

    申请号：US15878206

    申请日：2018-01-23

    申请人： MITRALTECH LTD.

    发明人： Ilia Hariton ,  Boaz Harari ,  Meni Iamberger ,  Aviram Baum

    IPC分类号： A61F2/24 ,  B23P15/00

    CPC分类号： A61F2/2415 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075 ,  A61F2250/0039 ,  B23P15/001

    摘要： In an unfolded state, a sheet defines a panel at a medial region, and tab portions disposed peripherally to the panel. A method comprises (A) sandwiching, between a first tab portion and a second tab portion, (i) a first commissural portion of a first leaflet, and (ii) a second commissural portion of a second leaflet; (B) attaching the first tab portion and the second tab portion to the sheet by stitching a first stitching through the tab portions and the commissural portions; (C) subsequently, covering the first stitching by: (i) forming the first tab portion into a first tab having an outer layer and an inner layer, and (ii) forming the second tab portion into a second tab having an outer layer and an inner layer; and (D) subsequently, stitching a second stitching through the outer and inner layers, and the commissural portions. Other embodiments are also described.

    ROLLED PROSTHETIC VALVE SUPPORT
    5.
    发明申请
    ROLLED PROSTHETIC VALVE SUPPORT 审中-公开

    公开(公告)号：US20170252159A1

    公开(公告)日：2017-09-07

    申请号：US15600190

    申请日：2017-05-19

    申请人： MITRALTECH LTD.

    发明人： Gil HACOHEN ,  Eran MILLER ,  Tal REICH ,  Yuval ZIPORY ,  Rotem NEEMAN ,  Natalia KRUGLOVA

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2250/0098

    摘要： Apparatus is provided for use at a native valve of a heart of a subject. The apparatus includes a delivery tube, transluminally advanceable to the heart; and a prosthetic valve support, configured to support a prosthetic valve at the native valve, and comprising an upstream support portion. The upstream support portion has a working configuration in which it is generally annular and has (1) a tissue-contacting side configured to be placed against an atrial surface of the native valve, and (2) an opposing side, and defines an opening therebetween. The upstream support portion also has a delivery configuration in which the upstream support portion is rolled up to define a channel, and is disposed within the delivery tube. The upstream support portion is configured to be transitioned from the delivery configuration to the working configuration by being exposed from the delivery tube, and unrolled.

    Percutaneously-deliverable mechanical valve
    7.
    发明授权
    Percutaneously-deliverable mechanical valve 有权
    经皮输送机械阀

    公开(公告)号：US09498332B2

    公开(公告)日：2016-11-22

    申请号：US14442541

    申请日：2013-11-13

    申请人： MITRALTECH LTD.

    发明人： Gili Hacohen ,  Yuval Zipory ,  Tal Reich ,  Eran Miller ,  Amir Gross

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2403 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2220/0008 ,  A61F2220/0041 ,  A61F2230/0013 ,  A61F2230/005

    摘要： Apparatus for regulating blood flow of a subject is provided, the apparatus comprising a prosthetic valve (20) that comprises a tubular element (22), shaped to define a lumen (23) therethrough, and a valve member (24), configured to be coupled to the tubular element (22) and to be disposed within the lumen (23). The prosthetic valve (20) has (1) a compressed configuration in which the lumen (23) has a compressed width, the valve member (24) is generally cylindrical, and the prosthetic valve (20) is configured to be percutaneously delivered into the subject, and (2) an expanded configuration in which the lumen (23) has an expanded width that is greater than the compressed width, and the valve member (24) is generally disc-shaped, is coupled to the tubular element (22), and is disposed within the lumen (23). Other embodiments are also described.

    摘要翻译： 提供了一种用于调节受试者血液流动的装置，该装置包括一个人造瓣膜（20），该假体阀（20）包括管状元件（22），该管状元件成形为限定通过其的内腔（23），以及阀构件（24） 耦合到管状元件（22）并且设置在管腔（23）内。 假体阀（20）具有（1）压缩构造，其中管腔（23）具有压缩宽度，阀构件（24）大致为圆柱形，并且人造瓣膜（20）构造成经皮递送到 主体和（2）扩张构型，其中内腔（23）具有大于压缩宽度的扩展宽度，并且阀构件（24）大致为圆盘形，联接到管状元件（22） ，并设置在内腔（23）内。 还描述了其它实施例。

    MINIMALLY-INVASIVE DELIVERY SYSTEMS
    8.
    发明申请
    MINIMALLY-INVASIVE DELIVERY SYSTEMS 审中-公开

    公开(公告)号：US20190231525A1

    公开(公告)日：2019-08-01

    申请号：US16318025

    申请日：2016-08-01

    申请人： MITRALTECH LTD.

    发明人： Ilia HARITON ,  Boaz HARARI ,  Michael ALBITOV ,  Paul KAYE

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2436 ,  A61F2/2433 ,  A61F2/966 ,  A61F2002/9583

    摘要： A tool (410) for use with an implant (20) includes a housing (426) and a controller (440). The housing includes a tubular wall (428) that circumscribes a longitudinal axis; is dimensioned to house at least part of the implant; and defines a track (430) that follows a generally-helical path around the longitudinal axis. The controller includes a rod (442) that extends from a proximal part of the tool to the housing; and an actuator (444). The actuator is fixedly coupled to the rod, includes an engaging element (446) that engages the track, and is rotatable with respect to the housing. The controller and the housing mechanically cooperate such that rotation of the actuator with respect to the housing slides the housing longitudinally with respect to the actuator. Other embodiments are also described.

    Percutaneously-deliverable mechanical valve
    9.
    发明授权
    Percutaneously-deliverable mechanical valve 有权

    公开(公告)号：US10045845B2

    公开(公告)日：2018-08-14

    申请号：US15354504

    申请日：2016-11-17

    申请人： MITRALTECH LTD.

    发明人： Gil Hacohen ,  Yuval Zipory ,  Tal Reich ,  Eran Miller ,  Amir Gross

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2403 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2220/0008 ,  A61F2220/0041 ,  A61F2230/0013 ,  A61F2230/005

    摘要： Apparatus for regulating blood flow of a subject is provided, the apparatus comprising a prosthetic valve (20) that comprises a tubular element (22), shaped to define a lumen (23) therethrough, and a valve member (24), configured to be coupled to the tubular element (22) and to be disposed within the lumen (23). The prosthetic valve (20) has (1) a compressed configuration in which the lumen (23) has a compressed width, the valve member (24) is generally cylindrical, and the prosthetic valve (20) is configured to be percutaneously delivered into the subject, and (2) an expanded configuration in which the lumen (23) has an expanded width that is greater than the compressed width, and the valve member (24) is generally disc-shaped, is coupled to the tubular element (22), and is disposed within the lumen (23). Other embodiments are also described.

    MINIMALLY-INVASIVE DELIVERY SYSTEMS
    10.
    发明申请
    MINIMALLY-INVASIVE DELIVERY SYSTEMS 审中-公开

    公开(公告)号：US20180185148A1

    公开(公告)日：2018-07-05

    申请号：US15899858

    申请日：2018-02-20

    申请人： MITRALTECH LTD.

    发明人： Ilia HARITON ,  Boaz HARARI ,  Maxim KARALNIK ,  Michael ALBITOV ,  Meni IAMBERGER

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2436 ,  A61F2/2433 ,  A61F2/966 ,  A61F2002/9583

    摘要： A tool is configured for transluminal delivery of an implant. The tool has a proximal part and a distal part, and comprises a shaft, a nosepiece, a sheath, and a balloon. The nosepiece is fixed to the shaft, and is arranged with respect to the implant such that the implant extends proximally away from the nosepiece and over the shaft. The sheath houses the implant. The balloon is disposed at the distal part of the tool, and is in fluid communication with the proximal part of the tool. When maximally inflated, the balloon has (i) a widest part that has an inflated diameter that is less than the diameter of the sheath or at most 10 percent greater than the diameter of the sheath, and (ii) a tapered portion that tapers longitudinally away from the widest part and from the nosepiece.