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    Method and system for processing measurement data for website statistics
    1.
    发明授权
    Method and system for processing measurement data for website statistics 有权
    用于处理网站统计数据的方法和系统

    公开(公告)号：US09372900B2

    公开(公告)日：2016-06-21

    申请号：US12538666

    申请日：2009-08-10

    申请人： João Manuel Pinto Filipe ,  Pleun Christiaan Bel ,  Tiago Cipriano Pires ,  Zoltán Papp

    发明人： João Manuel Pinto Filipe ,  Pleun Christiaan Bel ,  Tiago Cipriano Pires ,  Zoltán Papp

    IPC分类号： G06F17/30

    CPC分类号： H04L67/22 ,  G06F17/30306 ,  G06F17/30536 ,  H04L43/062 ,  H04L67/02

    摘要： Methods and systems for storing web-site visitor data in a specific bucket among a plurality of buckets based on a unique visitor identifier. The methods and systems may dynamically change the number of buckets based on certain conditions, such as when one of the buckets reaches a predetermined size. Several processors may be used in parallel to process the visitor data from two or more of the buckets simultaneously, for example to generate or obtain report data. The systems and methods may aggregate the report data into a result table.

    摘要翻译： 用于基于唯一的访问者标识符将多个桶中的特定桶中的网站访问者数据存储的方法和系统。 方法和系统可以基于某些条件动态地改变桶的数量，例如当桶中的一个达到预定大小时。 可以并行使用几个处理器来同时处理来自两个或更多个桶的访问者数据，例如生成或获取报告数据。 系统和方法可以将报告数据聚合到结果表中。

    Antibodies to vertebrate serrate proteins and fragments
    6.
    发明授权
    Antibodies to vertebrate serrate proteins and fragments 失效
    脊椎动物对锯齿状蛋白和片段的抗体

    公开(公告)号：US06703489B1

    公开(公告)日：2004-03-09

    申请号：US09195524

    申请日：1998-11-19

    申请人： David Ish-Horowicz ,  Domingos Manuel Pinto Henrique ,  Julian Hart Lewis ,  Anna Mary Myat ,  Robert J. Fleming ,  Spyridon Artavanis-Tsakonas ,  Robert S. Mann ,  Grace E. Gray

    发明人： David Ish-Horowicz ,  Domingos Manuel Pinto Henrique ,  Julian Hart Lewis ,  Anna Mary Myat ,  Robert J. Fleming ,  Spyridon Artavanis-Tsakonas ,  Robert S. Mann ,  Grace E. Gray

    IPC分类号： A61K3824

    CPC分类号： C07K14/705 ,  A61K38/00 ,  C07K14/43504 ,  C07K14/43581 ,  C07K14/46 ,  C07K14/463 ,  C07K14/465

    摘要： The present invention relates to nucleotide sequences of Serrate genes, and amino acid sequences of their encoded proteins, as well as derivatives (e.g., fragments) and analogs thereof. In a specific embodiment, the Serrate protein is a human protein. The invention further relates to fragments (and derivatives and analogs thereof) of Serrate which comprise one or more domains of the Serrate protein, including but not limited to the intracellular domain, extracellular domain, DSL domain, cysteine rich domain, transmembrane region, membrane-associated region, or one or more EGF-like repeats of a Serrate protein, or any combination of the foregoing. Antibodies to Serrate, its derivatives and analogs, are additionally provided. Methods of production of the Serrate proteins, derivatives and analogs, e.g., by recombinant means, are also provided. Therapeutic and diagnostic methods and pharmaceutical compositions are provided. In specific examples, isolated Serrate genes, from Drosophila, chick, mouse, Xenopus and human, are provided.

    摘要翻译： 本发明涉及Serrate基因的核苷酸序列及其编码的蛋白质的氨基酸序列，以及衍生物（例如片段）及其类似物。 在一个具体实施方案中，所述丝氨酸蛋白是人蛋白质。 本发明还涉及含有一个或多个丝氨酸蛋白结构域的丝氨酸的片段（及其衍生物和类似物），包括但不限于细胞内结构域，细胞外结构域，DSL结构域，富含半胱氨酸的结构域，跨膜区， 或一种或多种丝裂蛋白的EGF样重复体，或前述的任何组合。 还提供了对Serrate及其衍生物和类似物的抗体。 还提供了通过重组方法生产丝氨酸蛋白质，衍生物和类似物的方法。 提供了治疗和诊断方法和药物组合物。 在具体实例中，提供了从果蝇，小鸡，小鼠，非洲爪蟾和人的分离的Serrate基因。

    Caddy for transporting a lawn mower operator
    7.
    发明授权
    Caddy for transporting a lawn mower operator 失效
    运送割草机操作员的球童

    公开(公告)号：US4828282A

    公开(公告)日：1989-05-09

    申请号：US173801

    申请日：1988-03-28

    申请人： Manuel Pinto

    发明人： Manuel Pinto

    IPC分类号： A01D34/00 ,  B62D51/00

    CPC分类号： A01D34/001 ,  B62D51/008 ,  A01D2101/00

    摘要： A caddy that is hitchable to a self-propelled power mower which comprises a pair of wheels and an axle for coupling the wheels including a main axle member which is positioned below the wheel center, an operator platform is mounted on the main axle such that the operator is positioned over the axle. The platform is located such that wheel centers are located in a vertical plane which substantially laterally bisects the platform so that the shifting rearwardly of the operator's weight cause concentration of the load on the wheels. A towbar is fixed to the axle and removably hitched to the mower. The wheel centers are located rearwardly from the main axle so that when the operator is normally positioned on the caddy a torque about the wheels centers is created that causes the towbar to apply a force at the mower.

    摘要翻译： 一种与自行式割草机相连的一个车轮，包括一对车轮和用于联接车轮的车轴，该车轮包括位于车轮中心下方的主轴构件，操作者平台安装在主车轴上，使得 操作员位于轴上。 平台的位置使得轮中心位于垂直平面中，该平面基本上横向平分平台，使得操作者的重量向后移动导致车轮上的负载集中。 拖杆固定在车轴上，并可拆卸地挂在割草机上。 车轮中心位于主轴后方，因此当操作员通常位于车架上时，产生了关于车轮中心的扭矩，导致拖杆在割草机上施加力。

    MULTI-THREAD BONE SCREW AND METHOD
    9.
    发明申请
    MULTI-THREAD BONE SCREW AND METHOD 有权
    多螺纹骨螺钉和方法

    公开(公告)号：US20120116464A1

    公开(公告)日：2012-05-10

    申请号：US13323546

    申请日：2011-12-12

    申请人： Franics Denis ,  Timothy A. Garvey ,  Joseph H. Perra ,  Manuel Pinto ,  James D. Schwender ,  Ensor Transfeldt ,  Michael S. Veldman ,  William A. Rezach

    发明人： Franics Denis ,  Timothy A. Garvey ,  Joseph H. Perra ,  Manuel Pinto ,  James D. Schwender ,  Ensor Transfeldt ,  Michael S. Veldman ,  William A. Rezach

    IPC分类号： A61B17/86

    CPC分类号： A61B17/863 ,  A61B17/7007 ,  A61B17/701 ,  A61B17/7032 ,  A61B17/7037 ,  A61B17/7038 ,  A61B17/7041 ,  A61B17/7059

    摘要： A bone screw comprises a threaded shank including a distal end portion and a proximal end portion, and defining a first threaded section extending from the distal end portion toward the proximal end portion and adapted for anchoring in cancellous bone. A second threaded section extends contiguously from the first threaded section toward the proximal end portion The second threaded section has a finer thread pattern relative to the first threaded section. In one embodiment, the first threaded section includes a first helical threading defining a single lead thread pattern for anchoring in cancellous bone, and the second threaded section includes a second helical threading interleaved with the first threading to define a duel lead thread pattern for engagement in cortical bone. In a further embodiment, the bone screw includes a head portion extending from the threaded shank and configured for coupling to a spinal implant.

    摘要翻译： 骨螺钉包括螺纹柄，所述螺纹柄包括远端部分和近端部分，并且限定从所述远端部分向近端部分延伸并适于锚固在松质骨中的第一螺纹部分。 第二螺纹部分从第一螺纹部分朝向近端部分连续延伸。第二螺纹部分相对于第一螺纹部分具有更细的螺纹图案。 在一个实施例中，第一螺纹部分包括限定用于锚固在松质骨中的单个引导线图案的第一螺旋螺纹，并且第二螺纹部分包括与第一螺纹交错的第二螺旋螺纹，以限定用于接合的导联螺纹图案 皮质骨。 在另一实施例中，骨螺钉包括从螺纹柄部延伸并被配置为联接到脊柱植入物的头部部分。