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公开(公告)号：US07827815B2
公开(公告)日：2010-11-09
申请号：US11737036
申请日：2007-04-18
申请人： Gary A. Carson , Marc E. Voorhees
发明人： Gary A. Carson , Marc E. Voorhees
IPC分类号： F25B27/00
CPC分类号： F25B17/08 , A61F7/0085 , A61F2007/0292 , A61F2007/126 , A61M5/1424 , A61M5/1483 , A61M5/445 , A61M2205/3606 , A61M2205/366 , F25D2400/12
摘要： A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.
摘要翻译： 公开了用于提供用于血管给药的冷却液体的便携式装置和方法。 便携式装置包括用于血管给药的液体源，用于从源接收液体的冷却储存器和用于通过基于吸附的方法冷却冷却储存器中的液体的吸附型热交换器。 热交换器可以包括用于接收和蒸发制冷剂的蒸发区域，用于吸附蒸发的制冷剂的吸附材料，以及用于将来自冷却储存器中的液体的热能传导到蒸发区域的热交换构件。 可以提供另外的组件，用于流体地互连和控制从源到冷却储存器以及从冷却储存器到血管界面装置的液体流动。 这种组合物可以与至少冷却储存器一起以消毒方式方便地包装。
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2.发明申请公开(公告)号：US20090299287A1
公开(公告)日：2009-12-03
申请号：US12467884
申请日：2009-05-18
申请人： Gary A. Carson , Marc E. Voorhees
发明人： Gary A. Carson , Marc E. Voorhees
CPC分类号： F25B17/08 , A61F7/0085 , A61F2007/0292 , A61F2007/126 , A61M5/1424 , A61M5/1483 , A61M5/445 , A61M2205/3606 , A61M2205/366 , F25D2400/12
摘要： A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.
摘要翻译： 公开了用于提供用于血管给药的冷却液体的便携式装置和方法。 便携式装置包括用于血管给药的液体源，用于从源接收液体的冷却储存器和用于通过基于吸附的方法冷却冷却储存器中的液体的吸附型热交换器。 热交换器可以包括用于接收和蒸发制冷剂的蒸发区域，用于吸附蒸发的制冷剂的吸附材料，以及用于将来自冷却储存器中的液体的热能传导到蒸发区域的热交换构件。 可以提供另外的组件，用于流体地互连和控制从源到冷却储存器以及从冷却储存器到血管界面装置的液体流动。 这种组合物可以与至少冷却储存器一起以消毒方式方便地包装。
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3.发明授权Method and apparatus for providing non-invasive ultrasound heating of the preoptic anterior hypothalamus 有权用于提供前视前下丘脑非侵入性超声加热的方法和装置公开(公告)号：US07044960B2
公开(公告)日：2006-05-16
申请号：US10666902
申请日：2003-09-17
申请人： Marc E. Voorhees , Gary A. Carson
发明人： Marc E. Voorhees , Gary A. Carson
CPC分类号： A61F7/02 , A61B8/0816 , A61F7/10 , A61N7/00
摘要： A method and system is provided to induce mild hypothermia in a patient through controlled heating of the preoptic anterior hypothalamus (POAH) in conjunction with cooling of patient's body. The system employs an ultrasound transducer that may be positioned extracorporeally to a patient skull for emitting ultrasound energy to the POAH. The ultrasound energy heats the POAH to inhibit thermoregulatory responses of the body such that a cooling means may more effectively cool bodily tissue in order to reduce a patient's core body temperature. Feedback sensors may be positioned at various locations on the patient in order to monitor the patient's core body temperature. A control apparatus included with the system controls the amount of heat the POAH receives and the amount of cooling the body receives based on the feedback signals from the sensors.
摘要翻译： 提供了一种方法和系统，通过与患者身体的冷却相结合，对前房前下丘脑（POAH）进行控制加热来诱导患者轻度低温。 该系统采用超声换能器，该超声换能器可以被定位在患者颅骨的体外以向POAH发射超声波能量。 超声能量加热POAH以抑制身体的体温调节反应，使得冷却装置可以更有效地冷却身体组织，以减少患者的核心体温。 反馈传感器可以位于患者的不同位置，以便监测患者的核心体温。 系统中包括的控制装置根据来自传感器的反馈信号来控制POAH接收的热量和身体的冷却量。
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公开(公告)号：US5626759A
公开(公告)日：1997-05-06
申请号：US284057
申请日：1994-08-01
CPC分类号： B01D63/16 , A61M1/1627 , A61M1/1698 , A61M1/26
摘要： A medical device and method for affecting mass transfer between blood and a fluid. In one application, this mass transfer is an oxygenation of the blood. Generally, a membrane which separates the blood and fluid is moved in a predetermined manner and in a direction which is substantially parallel to that of the primary direction of the flow to augment the mass transfer efficiency/rate. Importantly, this movement of the membrane is relative to the blood mass transfer boundary layer which steepens or increases the oxygen concentration gradient and decreases the thickness of the blood mass transfer boundary layer and thereby improves upon the mass transfer efficiency/rate of oxygen into the blood.
摘要翻译： 一种用于影响血液和液体之间的传质的医疗装置和方法。 在一个应用中，这种传质是血液的氧合。 通常，分离血液和流体的膜以预定的方式和基本上平行于流动的主要方向的方向移动，以增加传质效率/速率。 重要的是，膜的这种移动是相对于血液传质边界层，其使得陡峭或增加氧浓度梯度并降低血液传质边界层的厚度，从而改善传质效率/氧气进入血液的速率 。
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公开(公告)号：US07361186B2
公开(公告)日：2008-04-22
申请号：US10926279
申请日：2004-08-25
IPC分类号： A61F7/00
CPC分类号： A61F7/10 , A61F2007/0001 , A61F2007/0056 , A61K31/00 , A61K31/19 , A61K31/21 , A61K31/455 , A61K33/06
摘要： Active cooling of a person, such as to induce mild/moderate hypothermia, is accomplished by transferring heat from the persons body. Heat transfer and patient comfort are aided by administration of an anti-shivering drug and an anti-emetic drug.
摘要翻译： 通过从人体转移热量来实现人的主动冷却，例如诱发轻度/中度体温过低。 通过施用抗发抖药物和抗呕吐药物来辅助热传递和患者舒适。
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公开(公告)号：US08047010B2
公开(公告)日：2011-11-01
申请号：US12467884
申请日：2009-05-18
申请人： Gary A. Carson , Marc E. Voorhees
发明人： Gary A. Carson , Marc E. Voorhees
IPC分类号： F25B15/00
CPC分类号： F25B17/08 , A61F7/0085 , A61F2007/0292 , A61F2007/126 , A61M5/1424 , A61M5/1483 , A61M5/445 , A61M2205/3606 , A61M2205/366 , F25D2400/12
摘要： A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.
摘要翻译： 公开了用于提供用于血管给药的冷却液体的便携式装置和方法。 便携式装置包括用于血管给药的液体源，用于从源接收液体的冷却储存器和用于通过基于吸附的方法冷却冷却储存器中的液体的吸附型热交换器。 热交换器可以包括用于接收和蒸发制冷剂的蒸发区域，用于吸附蒸发的制冷剂的吸附材料，以及用于将来自冷却储存器中的液体的热能传导到蒸发区域的热交换构件。 可以提供另外的组件，用于流体地互连和控制从源到冷却储存器以及从冷却储存器到血管界面装置的液体流动。 这种组合物可以与至少冷却储存器一起以消毒方式方便地包装。
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