公开(公告)号：US20140135866A1

公开(公告)日：2014-05-15

申请号：US14127130

申请日：2012-07-05

Applicant: Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

Inventor： Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

IPC: A61N1/368 ,  A61N1/365

CPC classification number: A61N1/36585 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/04085 ,  A61B5/4836 ,  A61B5/7425 ,  A61B2576/023 ,  A61N1/3625 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/36514 ,  A61N1/36528 ,  A61N1/368 ,  A61N1/3684 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63 ,  G16H50/50

Abstract: A method can include providing (302) at least one parameter to control a therapy that is applied to at least one internal anatomical structure of a patient. Electrical data can be obtained from the patient (304), including electrical data acquired via a plurality of sensors during each of a plurality of iterations of the therapy. The electrical data can be analyzed (306) for a respective value of the at least one parameter of the therapy at each of the plurality of iterations of the applied therapy to compute an indication of at least one function of the at least one internal anatomical structure of the patient at each respective iteration of the applied therapy. The computed indication can be stored in memory (308). At least one parameter of the therapy can be adjusted (310) for delivery in a subsequent one of the plurality of iterations based on the indication of the at least one function.

Abstract translation: 方法可以包括提供（302）至少一个参数以控制应用于患者的至少一个内部解剖结构的治疗。 可以从患者（304）获得电数据，包括在治疗的多次迭代中的每一个期间通过多个传感器获取的电数据。 可以在所施加的治疗的多次迭代中的每一个处分析电数据（306）以获得治疗的至少一个参数的相应值，以计算至少一个内部解剖结构的至少一个功能的指示 在每次应用治疗的各个迭代中。 所计算的指示可以存储在存储器（308）中。 可以基于至少一个功能的指示，在多个迭代中的随后的一次迭代中调整治疗的至少一个参数（310）以进行递送。

公开(公告)号：US09078573B2

公开(公告)日：2015-07-14

申请号：US13882912

申请日：2011-11-03

Applicant: Charulatha Ramanathan ,  Harold Wodlinger ,  Maria Strom ,  Steven G. Arless ,  Ping Jia

Inventor： Charulatha Ramanathan ,  Harold Wodlinger ,  Maria Strom ,  Steven G. Arless ,  Ping Jia

IPC: A61B5/04 ,  A61B5/0402 ,  A61B5/0452 ,  A61B5/00 ,  A61B5/02 ,  A61B5/11 ,  A61B5/042 ,  A61N1/362 ,  A61N1/368

CPC classification number: A61B5/04012 ,  A61B5/0044 ,  A61B5/02028 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/1107 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/6801 ,  A61N1/362 ,  A61N1/3627 ,  A61N1/368

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Abstract translation: 系统和方法可以用于基于电气数据提供心脏功能的指示，例如机械功能的指示或心脏的血液动力学指示。 例如，用于评估心脏功能的方法可以包括确定分布在心脏的空间区域上的多个点的基于时间的电特性。 基于多个点的空间位置或多个点的基于时间的电特性中的至少一个，可以将多个点组合成至少两个点子集。 可以基于对于至少两个点的每一个的确定的基于时间的电特性的相对分析来量化心脏同步的指示。

公开(公告)号：US20130245473A1

公开(公告)日：2013-09-19

申请号：US13882912

申请日：2011-11-03

Applicant: Charulatha Ramanathan ,  Wodlinger Harold ,  Maria Strom ,  Steven G. Arless ,  Ping Jia

Inventor： Charulatha Ramanathan ,  Wodlinger Harold ,  Maria Strom ,  Steven G. Arless ,  Ping Jia

IPC: A61B5/04 ,  A61B5/02 ,  A61B5/00 ,  A61B5/0402

CPC classification number: A61B5/04012 ,  A61B5/0044 ,  A61B5/02028 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/1107 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/6801 ,  A61N1/362 ,  A61N1/3627 ,  A61N1/368

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

公开(公告)号：US09186515B2

公开(公告)日：2015-11-17

申请号：US14127130

申请日：2012-07-05

Applicant: Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

Inventor： Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

IPC: A61N1/368 ,  A61N1/365 ,  A61B5/04 ,  A61B5/0402 ,  G06F19/00 ,  A61B5/00 ,  A61B5/0408 ,  A61N1/362

CPC classification number: A61N1/36585 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/04085 ,  A61B5/4836 ,  A61B5/7425 ,  A61B2576/023 ,  A61N1/3625 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/36514 ,  A61N1/36528 ,  A61N1/368 ,  A61N1/3684 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63 ,  G16H50/50

Abstract: A method can include providing (302) at least one parameter to control a therapy that is applied to at least one internal anatomical structure of a patient. Electrical data can be obtained from the patient (304), including electrical data acquired via a plurality of sensors during each of a plurality of iterations of the therapy. The electrical data can be analyzed (306) for a respective value of the at least one parameter of the therapy at each of the plurality of iterations of the applied therapy to compute an indication of at least one function of the at least one internal anatomical structure of the patient at each respective iteration of the applied therapy. The computed indication can be stored in memory (308). At least one parameter of the therapy can be adjusted (310) for delivery in a subsequent one of the plurality of iterations based on the indication of the at least one function.

Abstract translation: 方法可以包括提供（302）至少一个参数以控制应用于患者的至少一个内部解剖结构的治疗。 可以从患者（304）获得电数据，包括在治疗的多次迭代中的每一个期间通过多个传感器获取的电数据。 可以在所施加的治疗的多次迭代中的每一个处分析电数据（306）以获得治疗的至少一个参数的相应值，以计算至少一个内部解剖结构的至少一个功能的指示 在每次应用治疗的各个迭代中。 所计算的指示可以存储在存储器（308）中。 可以基于至少一个功能的指示，在多个迭代中的随后的一次迭代中调整治疗的至少一个参数（310）以进行递送。