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    Signal averaging
    1.
    发明授权
    Signal averaging 有权
    信号平均

    公开(公告)号：US09504427B2

    公开(公告)日：2016-11-29

    申请号：US14115235

    申请日：2012-05-04

    Applicant: Brian P. George ,  Remi Dubois ,  Charulatha Ramanathan ,  Harold Wodlinger

    Inventor： Brian P. George ,  Remi Dubois ,  Charulatha Ramanathan ,  Harold Wodlinger

    IPC: G01N33/48 ,  A61B5/00 ,  A61B5/0402 ,  A61B5/0452 ,  G06K9/00 ,  G06G7/58 ,  A61B5/0408 ,  A61B5/042

    CPC classification number: A61B5/7235 ,  A61B5/04028 ,  A61B5/04085 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7278 ,  G06K9/0051 ,  G06K9/00543

    Abstract: A method (500) can comprise performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template (530). The method can also comprise calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead (540). The method can further comprise detecting peak correlation coefficients in the virtual lead (550). The method can still further comprise comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead (560). The method can yet further comprise averaging the ROIs to generate averaged data (570).

    Abstract translation: 方法（500）可以包括对与多个信号的子集对应的数据和所选择的模板执行主成分分析（PCA），以生成虚拟引导和优化的模板（530）。 该方法还可以包括计算虚拟引线和优化模板上的互相关，以确定虚拟引线和优化模板之间的线性依赖性的强度，以确定虚拟引线（540）的感兴趣区域（ROI）。 该方法还可以包括检测虚拟引线中的峰值相关系数（550）。 该方法还可以包括将虚拟引线的每个ROI的幅度与所选择的模板进行比较，以确定模板与虚拟引线的每个ROI之间的误差（560）。 该方法还可以包括平均ROI以产生平均数据（570）。

    SIGNAL AVERAGING
    3.
    发明申请
    SIGNAL AVERAGING 有权
    信号平均

    公开(公告)号：US20140067279A1

    公开(公告)日：2014-03-06

    申请号：US14115235

    申请日：2012-05-04

    Applicant: Brian P. George ,  Remi Dubois ,  Charulatha Ramanathan ,  Harold Wodlinger

    Inventor： Brian P. George ,  Remi Dubois ,  Charulatha Ramanathan ,  Harold Wodlinger

    IPC: A61B5/00

    CPC classification number: A61B5/7235 ,  A61B5/04028 ,  A61B5/04085 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7278 ,  G06K9/0051 ,  G06K9/00543

    Abstract: A method (500) can comprise performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template (530). The method can also comprise calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead (540). The method can further comprise detecting peak correlation coefficients in the virtual lead (550). The method can still further comprise comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead (560). The method can yet further comprise averaging the ROIs to generate averaged data (570).

    Abstract translation: 方法（500）可以包括对与多个信号的子集对应的数据和所选择的模板执行主成分分析（PCA），以生成虚拟引导和优化的模板（530）。 该方法还可以包括计算虚拟引线和优化模板上的互相关，以确定虚拟引线和优化模板之间的线性依赖性的强度，以确定虚拟引线（540）的感兴趣区域（ROI）。 该方法还可以包括检测虚拟引线中的峰值相关系数（550）。 该方法还可以包括将虚拟引线的每个ROI的幅度与所选择的模板进行比较，以确定模板与虚拟引线的每个ROI之间的误差（560）。 该方法还可以包括平均ROI以产生平均数据（570）。

    System for determining the first prematurity contact of dental occlusion
    4.
    发明授权
    System for determining the first prematurity contact of dental occlusion 失效
    用于确定牙齿闭塞的第一次早产儿接触的系统

    公开(公告)号：US4521186A

    公开(公告)日：1985-06-04

    申请号：US495555

    申请日：1983-05-17

    Applicant: Harold Wodlinger ,  Hart V. Katz

    Inventor： Harold Wodlinger ,  Hart V. Katz

    IPC: A61C9/00 ,  A61C19/05

    CPC classification number: A61C19/05 ,  A61C9/00

    Abstract: A system for determining the first dental occlusion prematurity is presented. A sensor adapted to be inserted in the mouth of a patient comprises two flexible strips with spaced electrical conductors connected to a liquid crystal display. Each of the strips has a layer of dilatant material on one side. When the patient bites, the upper and lower conductors complete an electrical circuit and from the resistance of this circuit the location of the first prematurity relative to the strip is determined. One edge of the strip is used as a reference point on the sensor and the distance from this edge to the location is displayed on the liquid crystal display. The dilatant layer also retains the impression of the teeth and the location identified by the visual display and the impression are compared to give the exact location of the first prematurity. The sensor is reusable on the same patient to determine subsequent prematurities by squeezing it to remove the impression of teeth on the original bite.

    Abstract translation: 提出了一种用于确定第一种牙齿闭塞性早熟的系统。 适于插入患者口中的传感器包括具有连接到液晶显示器的间隔电导体的两个柔性带。 每个条带在一侧具有一层膨胀材料。 当患者咬住时，上下导体完成一个电路，并且从该电路的电阻确定第一早熟相对于条带的位置。 该条的一个边缘用作传感器上的参考点，并且从该边缘到该位置的距离显示在液晶显示器上。 扩张层还保留了牙齿的印象和由视觉显示所识别的位置，并且比较印象以给出第一早熟的确切位置。 传感器可重复使用在同一名病人身上，以便通过挤压它来消除原来咬伤牙齿的印象。

    LOCALIZATION FOR ELECTROCARDIOGRAPHIC MAPPING
    6.
    发明申请
    LOCALIZATION FOR ELECTROCARDIOGRAPHIC MAPPING 审中-公开
    电子地图绘制的本地化

    公开(公告)号：US20140235989A1

    公开(公告)日：2014-08-21

    申请号：US14127136

    申请日：2012-07-05

    Applicant: Harold Wodlinger ,  Charulatha Ramanathan ,  Ping Jia

    Inventor： Harold Wodlinger ,  Charulatha Ramanathan ,  Ping Jia

    IPC: A61B5/06 ,  A61N1/362 ,  A61B18/14 ,  A61B5/042 ,  A61B5/00

    CPC classification number: A61B5/063 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/066 ,  A61B5/4836 ,  A61B18/1492 ,  A61B34/20 ,  A61B2034/2053 ,  A61N1/362 ,  A61N1/3625 ,  A61N1/3628

    Abstract: A system (10) can localize an object in a patient's body. The system (10) can include a pulse generator (18 or 30) configured to provide a localization signal to at least one electrode that is fixed to the object in the patient's body. A sensor array (22) can be configured to detect an electrical field produced in response to the localization signal and provide respective sensor signals. A map generator (42) can be configured to reconstruct electrical signals based on the respective sensor signals and geometry data representing a geometric relationship between patient anatomy and the sensor array. A location calculator (50) can determine a location where the localization signal was applied based on the reconstructed electrical signals.

    Abstract translation: 系统（10）可以将患者体内的物体定位。 系统（10）可以包括脉冲发生器（18或30），脉冲发生器（18或30）被配置为向固定到患者体内的物体的至少一个电极提供定位信号。 传感器阵列（22）可以被配置为检测响应于定位信号而产生的电场并提供相应的传感器信号。 地图生成器（42）可以被配置为基于相应的传感器信号和表示患者解剖结构和传感器阵列之间的几何关系的几何数据来重建电信号。 位置计算器（50）可以基于重建的电信号来确定应用定位信号的位置。

    SYSTEM AND METHODS TO FACILITATE PROVIDING THERAPY TO A PATIENT
    7.
    发明申请
    SYSTEM AND METHODS TO FACILITATE PROVIDING THERAPY TO A PATIENT 有权
    为患者提供治疗的系统和方法

    公开(公告)号：US20140135866A1

    公开(公告)日：2014-05-15

    申请号：US14127130

    申请日：2012-07-05

    Applicant: Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

    Inventor： Charulatha Ramanathan ,  Harold Wodlinger ,  Ping Jia ,  Maria Strom

    IPC: A61N1/368 ,  A61N1/365

    CPC classification number: A61N1/36585 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/04085 ,  A61B5/4836 ,  A61B5/7425 ,  A61B2576/023 ,  A61N1/3625 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/36514 ,  A61N1/36528 ,  A61N1/368 ,  A61N1/3684 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63 ,  G16H50/50

    Abstract: A method can include providing (302) at least one parameter to control a therapy that is applied to at least one internal anatomical structure of a patient. Electrical data can be obtained from the patient (304), including electrical data acquired via a plurality of sensors during each of a plurality of iterations of the therapy. The electrical data can be analyzed (306) for a respective value of the at least one parameter of the therapy at each of the plurality of iterations of the applied therapy to compute an indication of at least one function of the at least one internal anatomical structure of the patient at each respective iteration of the applied therapy. The computed indication can be stored in memory (308). At least one parameter of the therapy can be adjusted (310) for delivery in a subsequent one of the plurality of iterations based on the indication of the at least one function.

    Abstract translation: 方法可以包括提供（302）至少一个参数以控制应用于患者的至少一个内部解剖结构的治疗。 可以从患者（304）获得电数据，包括在治疗的多次迭代中的每一个期间通过多个传感器获取的电数据。 可以在所施加的治疗的多次迭代中的每一个处分析电数据（306）以获得治疗的至少一个参数的相应值，以计算至少一个内部解剖结构的至少一个功能的指示 在每次应用治疗的各个迭代中。 所计算的指示可以存储在存储器（308）中。 可以基于至少一个功能的指示，在多个迭代中的随后的一次迭代中调整治疗的至少一个参数（310）以进行递送。

    Localization for electrocardiographic mapping
    10.
    发明授权
    Localization for electrocardiographic mapping 有权

    公开(公告)号：US10506948B2

    公开(公告)日：2019-12-17

    申请号：US14127136

    申请日：2012-07-05

    Applicant: Harold Wodlinger ,  Charulatha Ramanathan ,  Ping Jia

    Inventor： Harold Wodlinger ,  Charulatha Ramanathan ,  Ping Jia

    IPC: A61B5/06 ,  A61B5/042 ,  A61B18/14 ,  A61N1/362 ,  A61B34/20 ,  A61B5/0402 ,  A61B5/00

    Abstract: A system (10) can localize an object in a patient's body. The system (10) can include a pulse generator (18 or 30) configured to provide a localization signal to at least one electrode that is fixed to the object in the patient's body. A sensor array (22) can be configured to detect an electrical field produced in response to the localization signal and provide respective sensor signals. A map generator (42) can be configured to reconstruct electrical signals based on the respective sensor signals and geometry data representing a geometric relationship between patient anatomy and the sensor array. A location calculator (50) can determine a location where the localization signal was applied based on the reconstructed electrical signals.

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