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公开(公告)号:US5763420A
公开(公告)日:1998-06-09
申请号:US450930
申请日:1995-05-25
申请人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
发明人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
IPC分类号: C12P19/04 , A61K31/70 , A61K31/715 , A61P7/02 , A61P13/02 , A61P15/00 , A61P37/08 , C07H13/04 , C12R1/01 , A61K31/735
CPC分类号: A61K31/715 , A61K31/70 , A61K31/7012 , A61K31/7016 , A61K31/702 , C07H13/04 , Y10S514/825 , Y10S514/885
摘要: An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts, thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.
摘要翻译: 一种抗炎药,其包含选自科洛芬酸,聚洛米酸的部分水解产物和其药学上可接受的盐的至少一种化合物作为有效成分。 该药用作肾脏疾病的药物,用于肝炎的药物,免疫调节剂和抑制嗜中性粒细胞趋化性的药物。
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公开(公告)号:US5516764A
公开(公告)日:1996-05-14
申请号:US219236
申请日:1994-03-28
申请人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
发明人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
IPC分类号: C12P19/04 , A61K31/70 , A61K31/715 , A61P7/02 , A61P13/02 , A61P15/00 , A61P37/08 , C07H13/04 , C12R1/01 , A01N43/04 , C07H1/00
CPC分类号: A61K31/715 , A61K31/70 , A61K31/7012 , A61K31/7016 , A61K31/702 , C07H13/04 , Y10S514/825 , Y10S514/885
摘要: An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.
摘要翻译: 一种抗炎药,其包含选自科洛芬酸,聚洛米酸的部分水解产物和其药学上可接受的盐中的至少一种化合物作为有效成分。 该药用作肾脏疾病的药物,用于肝炎的药物,免疫调节剂和抑制嗜中性粒细胞趋化性的药物。
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公开(公告)号:US5668115A
公开(公告)日:1997-09-16
申请号:US450699
申请日:1995-05-25
申请人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
发明人: Ryoichi Osawa , Isao Suda , Masaaki Numata , Mamoru Sugimoto , Kenkichi Tomita , Nobuyuki Kibushi , Takayuki Ishii , Naokazu Sugiyama , Makiko Kasano , Tae Yasunaga , Makoto Tanaka , Tomoya Ogawa , Mariko Ishii
IPC分类号: C12P19/04 , A61K31/70 , A61K31/715 , A61P7/02 , A61P13/02 , A61P15/00 , A61P37/08 , C07H13/04 , C12R1/01
CPC分类号: A61K31/715 , A61K31/70 , A61K31/7012 , A61K31/7016 , A61K31/702 , C07H13/04 , Y10S514/825 , Y10S514/885
摘要: An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.
摘要翻译: 一种抗炎药,其包含选自科洛芬酸,聚洛米酸的部分水解产物和其药学上可接受的盐中的至少一种化合物作为有效成分。 该药用作肾脏疾病的药物,用于肝炎的药物,免疫调节剂和抑制嗜中性粒细胞趋化性的药物。
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公开(公告)号:US5393742A
公开(公告)日:1995-02-28
申请号:US109614
申请日:1993-08-19
申请人: Takayuki Ishii , Makiko Kasano , Tae Yasunaga , Mariko Ishii , Mamoru Sugimoto , Kenkichi Tomita , Takeshi Miyata , Makoto Tanaka
发明人: Takayuki Ishii , Makiko Kasano , Tae Yasunaga , Mariko Ishii , Mamoru Sugimoto , Kenkichi Tomita , Takeshi Miyata , Makoto Tanaka
IPC分类号: A61K31/70
CPC分类号: A61K31/7004 , A61K31/70
摘要: A preparation is useful for treating renal disease, such as nephritis and especially nephrosis (nephrotic syndrome), which comprises an effective amount of N-acetylneuraminic acid shown by the formula ##STR1## wherein, when n is 1, Z represents hydrogens, lithium, potassium, sodium, ammonium or organic ammonium, and when n is 2, Z represents calcium, barium or magnesium, and a pharmacologically acceptable carrier.
摘要翻译: 一种制剂可用于治疗肾脏疾病,例如肾炎,特别是肾病(肾病综合征),其包含有效量的由马来酰亚胺,锂,钾,钠,铵或有机铵显示的N-乙酰神经氨酸,当n为 2,Z表示钙,钡或镁,以及药理学上可接受的载体。
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