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1.发明申请INTEGRATED MEDICAL APPARATUS FOR NON-TRAUMATIC GRASPING, MANIPULATING AND CLOSURE OF TISSUE 审中-公开用于非手术治疗，组织和组织闭合的综合医疗器械公开(公告)号：US20120239081A1
公开(公告)日：2012-09-20
申请号：US13441299
申请日：2012-04-06
申请人： Mark J. Gartner , Brian J. Fill
发明人： Mark J. Gartner , Brian J. Fill
IPC分类号： A61B17/28
CPC分类号： A61B17/0057 , A61B17/12013 , A61B17/221 , A61B17/29 , A61B17/32056 , A61B2017/00243 , A61B2017/003 , A61B2017/00575 , A61B2017/00858 , A61B2017/00867 , A61B2017/2215 , A61B2017/2829 , A61B2017/2925 , A61B2017/301
摘要： The integrated medical apparatus includes an operator handle end and a multi-prong grasping member positioned within and movable relative to a grasper lumen that extends from the handle end, wherein the grasping prongs are moved between an open and closed position by relative axial movement between the prongs of the grasping member and the grasper lumen. The medical apparatus includes a contractible snare and a plurality of axially moveable snare pushing arms. At least two of the snare pushing arms include a snare holding and release mechanism, wherein the snare pushing arms are configured to advance the snare in an open, encircling position to a final deployed position where the snare can be released through the activation of the holding and release mechanism of the pushing arms, and finally tightened in a conventional fashion, such as pulling on an end of the snare at the handle end.
摘要翻译： 集成医疗装置包括操作者手柄端和多爪抓握构件，所述操作者手柄端部和多爪抓握构件相对于从手柄端延伸的抓紧器腔体可移动并且可移动，其中抓握插头通过相对于所述手柄端部之间的相对轴向移动而在打开和关闭位置之间移动 夹持部件和抓持器管腔的插脚。 医疗装置包括可收缩的圈套和多个可轴向移动的圈套推动臂。 所述圈套推动臂中的至少两个包括圈套保持和释放机构，其中，所述圈套推动臂被构造成将所述圈套推进到最终展开位置，所述最终展开位置可以通过所述保持件 并且推动臂的释放机构，并且最终以常规方式紧固，例如在手柄端拉动圈套的一端。
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2.发明申请DEVICE AND METHOD OF USE FOR FUNCTIONAL ISOLATION OF ANIMAL OR HUMAN TISSUES 审中-公开用于功能性分离动物或人体组织的装置和方法公开(公告)号：US20110295060A1
公开(公告)日：2011-12-01
申请号：US13204383
申请日：2011-08-05
IPC分类号： A61B1/00
CPC分类号： A61B17/12013 , A61B18/14 , A61B2017/00243 , A61B2017/00575 , A61B2017/306 , A61B2017/308 , A61B2018/00291
摘要： A method and apparatus for functionally occluding the lumen of the left atrial appendage (LAA) is provided. Access to the LAA is through an epicardial approach. The devices function to capture the LAA through various non-invasive means. After capturing the LAA with the devices and methods provided, a clamping device is preferably disposed about the base of the appendage. In certain embodiments, the appendage remains viable subsequent to the functional occlusion of the lumen.
摘要翻译： 提供了用于功能闭塞左心耳（LAA）的腔的方法和装置。 进入LAA是通过心外膜的方法。 该装置通过各种非侵入性手段捕获LAA。 在使用所提供的装置和方法捕获LAA之后，优选地围绕附件的基部设置夹紧装置。 在某些实施例中，附件在腔的功能性闭塞之后仍然是可行的。
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3.发明授权公开(公告)号：US08007504B2
公开(公告)日：2011-08-30
申请号：US12410323
申请日：2009-03-24
CPC分类号： A61B17/12013 , A61B18/14 , A61B2017/00243 , A61B2017/00575 , A61B2017/306 , A61B2017/308 , A61B2018/00291
摘要： A method and apparatus for functionally occluding the lumen of the left atrial appendage (LAA) is provided. Access to the LAA is through an epicardial approach. The devices function to capture the LAA through various non-invasive means. After capturing the LAA with the devices and methods provided, a clamping device is preferably disposed about the base of the appendage. In certain embodiments, the appendage remains viable subsequent to the functional occlusion of the lumen.
摘要翻译： 提供了用于功能闭塞左心耳（LAA）的腔的方法和装置。 进入LAA是通过心外膜的方法。 该装置通过各种非侵入性手段捕获LAA。 在使用所提供的装置和方法捕获LAA之后，优选地围绕附件的基部设置夹紧装置。 在某些实施例中，附件在腔的功能性闭塞之后仍然是可行的。
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4.发明授权公开(公告)号：US07527634B2
公开(公告)日：2009-05-05
申请号：US10439280
申请日：2003-05-14
CPC分类号： A61B17/12013 , A61B18/14 , A61B2017/00243 , A61B2017/00575 , A61B2017/306 , A61B2017/308 , A61B2018/00291
摘要： A method and apparatus for functionally occluding the lumen of the left atrial appendage (LAA) is provided. Access to the LAA is through an epicardial approach. The devices function to capture the LAA through various non-invasive means. After capturing the LAA with the devices and methods provided, a clamping device is preferably disposed about the base of the appendage. In certain embodiments, the appendage remains viable subsequent to the functional occlusion of the lumen.
摘要翻译： 提供了用于功能闭塞左心耳（LAA）的腔的方法和装置。 进入LAA是通过心外膜的方法。 该装置通过各种非侵入性手段捕获LAA。 在使用所提供的装置和方法捕获LAA之后，优选地围绕附件的基部设置夹紧装置。 在某些实施例中，附件在腔的功能性闭塞之后仍然是可行的。
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公开(公告)号：US10286126B2
公开(公告)日：2019-05-14
申请号：US14440562
申请日：2013-11-06
申请人： University of Pittsburgh—Of the Commonwealth System of Higher Education , J. Peter Rubin , Arielle A. Richter , Aaron T. Ledgerwood , Jessica C. Huynh , Mark J. Gartner , Kacey G. Marra , Stephen Holland
发明人： J. Peter Rubin , Arielle A. Richter , Aaron T. Ledgerwood , Jessica C. Huynh , Kacey G. Marra , Stephen Holland , Mark J. Gartner
摘要： A device for removing fat from a body can include a pair of nested hollow members that each has at least one opening and an adjustment means for adjusting the orientation of the nested hollow members from a first configuration to a second configuration to change an amount of overlap between openings in the nested hollow members. The nested members can be deformable to change the shape of the openings.
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公开(公告)号：US20150297810A1
公开(公告)日：2015-10-22
申请号：US14440562
申请日：2013-11-06
申请人： J. Peter RUBIN , Arielle A. RICHTER , Aaron T. LEDGERWOOD , Jessica C. HUYNH , Mark J. GARTNER , Kacey G. MARRA , Stephen HOLLAND
发明人： J. Peter Rubin , Arielle A. Richter , Aaron T. Ledgerwood , Jessica C. Huynh , Kacey G. Marra , Stephen Holland , Mark J. Gartner
CPC分类号： A61M1/0082 , A61B17/3431 , A61M1/008 , A61M2202/08
摘要： A device for removing fat from a body can include a pair of nested hollow members that each has at least one opening and an adjustment means for adjusting the orientation of the nested hollow members from a first configuration to a second configuration to change an amount of overlap between openings in the nested hollow members. The nested members can be deformable to change the shape of the openings.
摘要翻译： 用于从身体去除脂肪的装置可以包括一对嵌套的中空构件，每个具有至少一个开口和用于将嵌套的中空构件的取向从第一构型调整到第二构型的调整装置，以改变重叠的量 在嵌套的中空构件的开口之间。 嵌套构件可以变形以改变开口的形状。
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7.发明申请DEVICE AND METHOD OF USE FOR FUNCTIONAL ISOLATION OF ANIMAL OR HUMAN TISSUES 有权用于功能性分离动物或人体组织的装置和方法公开(公告)号：US20090182326A1
公开(公告)日：2009-07-16
申请号：US12410323
申请日：2009-03-24
CPC分类号： A61B17/12013 , A61B18/14 , A61B2017/00243 , A61B2017/00575 , A61B2017/306 , A61B2017/308 , A61B2018/00291
摘要： A method and apparatus for functionally occluding the lumen of the left atrial appendage (LAA) is provided. Access to the LAA is through an epicardial approach. The devices function to capture the LAA through various non-invasive means. After capturing the LAA with the devices and methods provided, a clamping device is preferably disposed about the base of the appendage. In certain embodiments, the appendage remains viable subsequent to the functional occlusion of the lumen.
摘要翻译： 提供了用于功能闭塞左心耳（LAA）的腔的方法和装置。 进入LAA是通过心外膜的方法。 该装置通过各种非侵入性手段捕获LAA。 在使用所提供的装置和方法捕获LAA之后，优选地围绕附件的基部设置夹紧装置。 在某些实施例中，附件在腔的功能性闭塞之后仍然是可行的。
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8.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 失效膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US06723284B1
公开(公告)日：2004-04-20
申请号：US09707040
申请日：2000-11-06
IPC分类号： A61M114
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2206/14 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/38 , B01D2321/2066 , B01D2321/2083 , Y10S128/03 , Y10S165/357
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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9.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 失效膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US07122151B2
公开(公告)日：2006-10-17
申请号：US10827400
申请日：2004-04-19
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2206/14 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/38 , B01D2321/2066 , B01D2321/2083 , Y10S128/03 , Y10S165/357
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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10.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 有权膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US06217826B1
公开(公告)日：2001-04-17
申请号：US09157815
申请日：1998-09-21
IPC分类号： A61M114
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1025 , A61M1/1086 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2205/33 , A61M2205/3303 , A61M2206/14 , B01D63/02 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/243 , B01D2313/38 , B01D2321/2041 , B01D2321/2066 , B01D2321/2083
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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