公开(公告)号：US20080125831A1

公开(公告)日：2008-05-29

申请号：US12028699

申请日：2008-02-08

申请人： Martha Morrell

发明人： Martha Morrell

IPC分类号： A61N1/05

CPC分类号： A61N1/36071 ,  A61N1/0531 ,  A61N1/0539 ,  A61N1/36082

摘要： A medical device is capable of delivering a form of stimulation (e.g., electrical stimulation) to a region of the cingulate cortex of the human brain to treat a neurological event, condition or disorder, especially an event, condition, or disorder that is psychiatric in nature, such as depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders. The device additionally or alternatively may be capable of detecting a biological marker or changes in a biological marker corresponding to the neurological event, condition or disorder. Methods of using the device are also disclosed.

摘要翻译： 医疗设备能够将一种刺激形式（例如，电刺激）传递到人类大脑的扣带皮质区域，以治疗神经系统事件，病症或障碍，特别是精神病学的事件，病症或障碍 自然，如抑郁症，双相情感障碍，焦虑和强迫症，创伤后应激障碍，成瘾，精神分裂症，孤独症和其他发育障碍。 该装置另外地或替代地可能能够检测对应于神经系统事件，病症或病症的生物标志物或生物标志物的变化。 还公开了使用该装置的方法。

公开(公告)号：US07353065B2

公开(公告)日：2008-04-01

申请号：US10941759

申请日：2004-09-14

申请人： Martha Morrell

发明人： Martha Morrell

IPC分类号： A61N1/05

CPC分类号： A61N1/36071 ,  A61N1/0531 ,  A61N1/0539 ,  A61N1/36082

摘要： An implantable neurostimulator system for treating psychiatric disorders includes scheduled and responsive therapy capabilities including responsive stimulation applied to the cingulate gyrus of the brain. Methods for treating depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders employ an inventive system to advantageously reduce symptoms and address underlying causes of the disorders.

摘要翻译： 用于治疗精神疾病的可植入神经刺激器系统包括计划和响应性治疗能力，包括应用于脑的扣带回的响应刺激。 用于治疗抑郁症，双相情感障碍，焦虑和强迫症，创伤后应激障碍，成瘾，精神分裂症和自闭症和其他发育障碍的方法使用创造性系统来有利地减少症状并解决疾病的潜在原因。

公开(公告)号：US20060058856A1

公开(公告)日：2006-03-16

申请号：US10941759

申请日：2004-09-14

申请人： Martha Morrell

发明人： Martha Morrell

IPC分类号： A61N1/34

CPC分类号： A61N1/36071 ,  A61N1/0531 ,  A61N1/0539 ,  A61N1/36082

摘要： An implantable neurostimulator system for treating psychiatric disorders includes scheduled and responsive therapy capabilities including responsive stimulation applied to the cingulate gyrus of the brain. Methods for treating depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders employ an inventive system to advantageously reduce symptoms and address underlying causes of the disorders.

摘要翻译： 用于治疗精神疾病的可植入神经刺激器系统包括计划和响应性治疗能力，包括应用于脑的扣带回的响应刺激。 用于治疗抑郁症，双相情感障碍，焦虑和强迫症，创伤后应激障碍，成瘾，精神分裂症和自闭症和其他发育障碍的方法使用创造性系统来有利地减少症状并解决疾病的潜在原因。

公开(公告)号：US20120109253A1

公开(公告)日：2012-05-03

申请号：US13347675

申请日：2012-01-10

申请人： Brett M. Wingeier ,  Martha Morrell ,  C. Lance Boling

发明人： Brett M. Wingeier ,  Martha Morrell ,  C. Lance Boling

IPC分类号： A61N1/36

CPC分类号： A61N1/0529 ,  A61N1/0536 ,  A61N1/0568

摘要： Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

摘要翻译： 描述医用电引线系统及相关方法。 医疗电引线系统可以被配置为至少部分地植入受试者的身体。 医疗电引线系统的一些变型可以包括引线主体，引线主体包括近端和远端以及至少部分延伸到其间的内腔，在引线主体的远端附近的至少一个电极和 与内腔流体连通，其中储存器位于从引线主体的远端移除的位置。 医疗电引线系统的某些变型可以包括引线本体，该引线主体包括近端和远端以及至少部分地延伸的第一和第二内腔以及在引线主体的远端附近的至少一个电极。

公开(公告)号：US08160720B2

公开(公告)日：2012-04-17

申请号：US12881171

申请日：2010-09-13

申请人： Brett M. Wingeier ,  Martha Morrell ,  Carl Lance Boling

发明人： Brett M. Wingeier ,  Martha Morrell ,  Carl Lance Boling

IPC分类号： A61N1/00

CPC分类号： A61N1/0529 ,  A61N1/0536 ,  A61N1/0568

摘要： Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

公开(公告)号：US20080125830A1

公开(公告)日：2008-05-29

申请号：US12028625

申请日：2008-02-08

申请人： Martha Morrell

发明人： Martha Morrell

IPC分类号： A61N1/05

CPC分类号： A61N1/36071 ,  A61N1/0531 ,  A61N1/0539 ,  A61N1/36082

摘要： An implantable medical device is capable of delivering a form of therapy (e.g., electrical stimulation) to a region of the cingulate cortex of a patient's brain to treat a neurological event, condition or disorder, especially an event, condition, or disorder that is psychiatric in nature, such as depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders. The apparatus is also capable of detecting a signal corresponding to a characteristic of the psychiatric disorder. Methods of using the apparatus are also disclosed.

摘要翻译： 可植入医疗装置能够将一种治疗形式（例如，电刺激）递送到患者大脑的扣带皮质的区域，以治疗神经系统事件，病症或障碍，特别是精神病学的事件，病症或病症 在自然界中，例如抑郁症，双相情感障碍，焦虑和强迫症，创伤后应激障碍，成瘾，精神分裂症和自闭症等发育障碍。 该装置还能够检测对应于精神障碍特征的信号。 还公开了使用该装置的方法。

公开(公告)号：US08190270B2

公开(公告)日：2012-05-29

申请号：US13347675

申请日：2012-01-10

申请人： Brett M. Wingeier ,  Martha Morrell ,  Carl Lance Boling

发明人： Brett M. Wingeier ,  Martha Morrell ,  Carl Lance Boling

IPC分类号： A61N1/00

CPC分类号： A61N1/0529 ,  A61N1/0536 ,  A61N1/0568

摘要： Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

摘要翻译： 描述医用电引线系统及相关方法。 医疗电引线系统可以被配置为至少部分地植入受试者的身体。 医疗电引线系统的一些变型可以包括引线主体，引线主体包括近端和远端以及至少部分延伸到其间的内腔，在引线主体的远端附近的至少一个电极和 与内腔流体连通，其中储存器位于从引线主体的远端移除的位置。 医疗电引线系统的某些变型可以包括引线本体，该引线主体包括近端和远端以及至少部分地延伸的第一和第二内腔以及在引线主体的远端附近的至少一个电极。