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公开(公告)号：US5547997A
公开(公告)日：1996-08-20
申请号：US769411
申请日：1991-10-01
Applicant: Martin Kludas
Inventor： Martin Kludas
IPC: A61K8/64 , A61K8/73 , A61K8/97 , A61K36/81 , A61Q5/00 , A61Q19/00 , A61Q19/08 , A61K47/00 , A61K35/78
Abstract: The invention provides compositions for the repair and remodelling of sun damaged and aged skin. The composition comprises a component of plant extracellular matrix extract in substantially native conformation, and can include a cosmetic carrier. In particular, the composition can include a glycoprotein of a plant extracellular matrix composition, a carbohydrate polymer of plant extracellular matrix composition, and mixtures thereof, each in substantially native conformation. Plant extracellular matrix extracts from Kudzu and maize are obtained.
Abstract translation: 本发明提供了用于修复和改造太阳损伤和老化皮肤的组合物。 组合物包含基本上天然构象的植物细胞外基质提取物的组分，并且可以包括化妆品载体。 特别地，组合物可以包括植物细胞外基质组合物的糖蛋白，植物细胞外基质组合物的碳水化合物聚合物及其混合物，其基本上是天然构象。 获得葛根和玉米的植物细胞外基质提取物。
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Patent Agency Ranking
公开(公告)号：US4464362A
公开(公告)日：1984-08-07
申请号：US355579
申请日：1982-02-23
Applicant: Martin Kludas , Dieter Heise
Inventor： Martin Kludas , Dieter Heise
CPC classification number: A61K8/99 , A61Q19/00 , A61Q19/004 , A61Q19/08
Abstract: Cosmetic compositions containing an active substance complex for promoting the DNA repair process of the skin cells, in order to guard against possible cellular skin damage due to excessive light influence, and to counteract the light-caused aging process of the skin. The active substance complex consists of inactivated cultures of bacteria of the genus Bifidobacterium or bacteria related to this genus.
Abstract translation: PCT No.PCT / EP81 / 00086 Sec。 371日期1982年2月23日 102（e）日期1982年2月23日PCT提交1981年6月26日PCT公布。 出版物WO82 / 00093 日期1982年1月21日。含有促进皮肤细胞DNA修复过程的活性物质复合物的化妆品组合物，以防止由于过度的光影响引起的可能的细胞性皮肤损伤，并抵消光引起的老化过程 皮。 活性物质复合物由双歧杆菌属细菌的灭活培养物或与该属相关的细菌组成。
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公开(公告)号：US5036056A
公开(公告)日：1991-07-30
申请号：US500330
申请日：1990-03-27
Applicant: Martin Kludas
Inventor： Martin Kludas
CPC classification number: A61K31/715 , A61K35/44 , A61K35/48 , A61K35/50 , A61K38/39 , C07K14/78 , Y10S514/912 , Y10S514/935
Abstract: Methods for treating damaged corneal, uterine or cartilage tissue comprising applying a therapeutically effective amount of a composition comprising:(a) a sterile extracellular connective tissue matrix composition comprising collagens, proteoglycans, glycosaminoglycans and glycoproteins wherein said collagens, said proteoglycans, said glycosamino glycans, and said glycoproteins have each been extracted from an extracellular connective tissue matrix and are in their native structural form and(b) a pharmaceutically acceptable carrier.
Abstract translation: 治疗损伤的角膜，子宫或软骨组织的方法包括施用治疗有效量的组合物，其包含：（a）包含胶原蛋白，蛋白聚糖，糖胺聚糖和糖蛋白的无菌细胞外结缔组织基质组合物，其中所述胶原蛋白，所述蛋白聚糖，所述糖胺聚糖， 并且所述糖蛋白各自是从细胞外结缔组织基质中提取并且是其天然结构形式和（b）药学上可接受的载体。
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公开(公告)号：US3991184A
公开(公告)日：1976-11-09
申请号：US536893
申请日：1974-12-27
Applicant: Martin Kludas , Gunter Borchert
Inventor： Martin Kludas , Gunter Borchert
Abstract: For the care of skin there is contemplated the use of untreated, soluble collagen having an unchanged substantially non-crosslinked collagen structure and obtained by the direct extraction from the connective tissue of skin.
Abstract translation: 为了保护皮肤，考虑使用未经处理的可溶性胶原，其具有基本上未交联的胶原结构，并且通过从皮肤的结缔组织直接提取获得。
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5.发明授权
公开(公告)号：US5055298A
公开(公告)日：1991-10-08
申请号：US917468
申请日：1986-10-10
Applicant: Martin Kludas
Inventor： Martin Kludas
IPC: A61K8/72 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/64 , A61K8/65 , A61K8/73 , A61K8/96 , A61K8/98 , A61Q1/00 , A61Q1/12 , A61Q5/02 , A61Q19/00 , A61Q19/08
CPC classification number: A61Q19/004 , A61K8/062 , A61K8/981 , A61K8/982 , A61Q19/08 , Y10S514/846
Abstract: A cosmetic agent for remodeling and repairing the basement membrane of aging human skin and/or human skin damaged, for example, by ultraviolet radiation. The agent contains the essential components of the extracellular connective tissue matrix in native form and in physiological proportions. The components are obtained from mammals.
Abstract translation: 用于重塑和修复老化的人体皮肤和/或人体皮肤的基底膜例如通过紫外线辐射损伤的化妆剂。 该药剂含有天然形式和生理比例的细胞外结缔组织基质的基本成分。 组分是从哺乳动物获得的。
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公开(公告)号：US4327078A
公开(公告)日：1982-04-27
申请号：US17773
申请日：1979-03-05
Applicant: Egbert Charlet , Martin Kludas
Inventor： Egbert Charlet , Martin Kludas
IPC: A61K8/72 , A61K8/64 , A61K8/65 , A61K8/96 , A61Q19/00 , A61Q19/08 , A61K7/00 , A61K7/42 , A61K7/48
CPC classification number: A61K8/64 , A61Q19/00 , A61Q19/08 , A61Q19/004
Abstract: The invention concerns the provision of cosmetic agents containing, as an active ingredient, soluble elastin. Also included is a method of combating skin ageing by applying said cosmetic agents to the skin.
Abstract translation: 本发明涉及提供含有可溶性弹性蛋白作为活性成分的化妆品。 还包括通过将所述化妆品施用于皮肤来对抗皮肤老化的方法。
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