公开(公告)号：US20100049182A1

公开(公告)日：2010-02-25

申请号：US12520022

申请日：2007-12-21

申请人： S. Eric Ryan ,  Jing Tang ,  Matthew Flinders

发明人： S. Eric Ryan ,  Jing Tang ,  Matthew Flinders

IPC分类号： A61B18/18

CPC分类号： A61B5/0075 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/6853 ,  A61B18/24 ,  A61B2017/00274 ,  A61B2017/22051 ,  A61B2018/00547 ,  A61B2562/146

摘要： Systems, methods, and apparatus for providing a fluid and reduced-toxicity optical media with optical analysis and therapeutic energy delivery. An aspect of the invention provides an aqueous solution of increased-salinity of between about 1% and 35%. An increasing salinity in accordance with the invention provides improved transmissive efficiency at many wavelengths and less toxicity than many existing systems and methods. A catheter having integrated fibers for probing or treating internal lumens or other tissues can include a liquid-inflatable balloon or flushing mechanism using the solution for displacing blood or other obstructions in an optical path between the fiber and targeted tissue. Methods including spectroscopy can be employed with the solution for diagnosing medical conditions associated with diseased vessels or other tissues while reducing the risk of permanent damage resulting from the diagnosis. Additional applications include the deliver of therapeutic radiation externally and internally to tissues through h the solution media.

摘要翻译： 用于提供具有光学分析和治疗能量递送的流体和减毒光学介质的系统，方法和装置。 本发明的一个方面提供了约1％至35％之间的增加盐度的水溶液。 根据本发明的增加的盐度提供了许多波长的改进的透射效率和比许多现有的系统和方法更少的毒性。 具有用于探测或治疗内部腔或其他组织的集成纤维的导管可以包括使用溶液替代在纤维和靶组织之间的光路中的血液或其它障碍物的液体充气球囊或冲洗机构。 可以使用包括光谱学的方法用于诊断与患病血管或其他组织相关的医学病症的解决方案，同时降低由诊断引起的永久性损伤的风险。 其他应用包括通过溶液介质在组织外部和内部传递治疗辐射。

公开(公告)号：US20160026005A1

公开(公告)日：2016-01-28

申请号：US14775670

申请日：2014-03-14

申请人： Matthew FLINDERS

发明人： Matthew Flinders

IPC分类号： G02C7/10 ,  G02C7/12

CPC分类号： G02C7/104 ,  G02B5/22 ,  G02C7/10 ,  G02C7/105 ,  G02C7/12

摘要： The invention relates to eye-wear and lenses for controlling and/or blocking the absorption of particular bandwidths of light that can impact the physiology of the wearer. The eyewear lens is adapted to selectively permit the relatively greatest percentage of a light within a wavelength range of between about 400 and 490 nanometers. The eyewear lens selectively permits the passage of light of the given wavelength range over one or more subregions of the eyewear lens. The one or more subregions cover in total at most 25-50% of the lens. The peak transmission level within the range between about 400 and 490 nanometers is at least about 70% and the passage of light outside of the range between about 400 and 490 nanometers is less than about 70%.

摘要翻译： 本发明涉及眼睛磨损和用于控制和/或阻挡能够影响佩戴者生理学的特定带宽光线的透镜。 眼镜透镜适于选择性地允许在约400和490纳米之间的波长范围内的相对最大百分比的光。 眼镜透镜选择性地允许在眼镜透镜的一个或多个子区域上通过给定波长范围的光。 一个或多个子区域总共覆盖了镜片的25-50％。 约400至490纳米之间范围内的峰值透射率水平至少约为70％，而在约400至490纳米范围之外的光通过量小于约70％。

公开(公告)号：US20210364826A1

公开(公告)日：2021-11-25

申请号：US17393279

申请日：2021-08-03

申请人： Matthew Flinders

发明人： Matthew Flinders

IPC分类号： G02C7/10 ,  G02B5/22 ,  G02C7/12

摘要： Eyeglasses and components thereof providing enhanced absorption to the wearer of light known for regulating mood and biological rhythms. The components include lenses designed to enhance and accentuate the absorption of particular wavelengths in the eye, including those wavelengths between about 400 and 490 nm, and for promoting this absorption in particularly sensitive areas of the eye.

公开(公告)号：US11086145B2

公开(公告)日：2021-08-10

申请号：US14775670

申请日：2014-03-14

申请人： Matthew Flinders

发明人： Matthew Flinders

IPC分类号： G02C7/10 ,  G02C7/12 ,  G02B5/22

摘要： The invention relates to eyewear and lenses for controlling and/or blocking the absorption of particular bandwidths of light that can impact the physiology of the wearer. The eyewear lens is adapted to selectively permit the relatively greatest percentage of a light within a wavelength range of between about 400 and 490 nanometers. The eyewear lens selectively permits the passage of light of the given wavelength range over one or more subregions of the eyewear lens. The one or more subregions cover in total at most 25-50% of the lens. The peak transmission level within the range between about 400 and 490 nanometers is at least about 70% and the passage of light outside of the range between about 400 and 490 nanometers is less than about 70%.

公开(公告)号：US09113785B2

公开(公告)日：2015-08-25

申请号：US12520022

申请日：2007-12-21

申请人： S. Eric Ryan ,  Jing Tang ,  Matthew Flinders

发明人： S. Eric Ryan ,  Jing Tang ,  Matthew Flinders

IPC分类号： A61B6/00 ,  A61B5/00 ,  A61B18/24 ,  A61B17/00 ,  A61B17/22 ,  A61B18/00

CPC分类号： A61B5/0075 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/6853 ,  A61B18/24 ,  A61B2017/00274 ,  A61B2017/22051 ,  A61B2018/00547 ,  A61B2562/146

摘要： Systems, methods, and apparatus for providing a fluid and reduced-toxicity optical media with optical analysis and therapeutic energy delivery. An aspect of the invention provides an aqueous solution of increased-salinity of between about 1% and 35%. An increasing salinity in accordance with the invention provides improved transmissive efficiency at many wavelengths and less toxicity than many existing systems and methods. A catheter having integrated fibers for probing or treating internal lumens or other tissues can include a liquid-inflatable balloon or flushing mechanism using the solution for displacing blood or other obstructions in an optical path between the fiber and targeted tissue. Methods including spectroscopy can be employed with the solution for diagnosing medical conditions associated with diseased vessels or other tissues while reducing the risk of permanent damage resulting from the diagnosis. Additional applications include the deliver of therapeutic radiation externally and internally to tissues through h the solution media.

摘要翻译： 用于提供具有光学分析和治疗能量递送的流体和减毒光学介质的系统，方法和装置。 本发明的一个方面提供了约1％至35％之间的增加盐度的水溶液。 根据本发明的增加的盐度提供了许多波长的改进的透射效率和比许多现有的系统和方法更少的毒性。 具有用于探测或治疗内部腔或其他组织的集成纤维的导管可以包括使用溶液替代在纤维和靶组织之间的光路中的血液或其它障碍物的液体可充气球囊或冲洗机构。 可以使用包括光谱学的方法用于诊断与患病血管或其他组织相关的医学病症的解决方案，同时降低由诊断引起的永久性损伤的风险。 其他应用包括通过溶液介质在组织外部和内部传递治疗辐射。