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公开(公告)号：US10112926B2
公开(公告)日：2018-10-30
申请号：US15303879
申请日：2014-04-24
Applicant: Benjamin Richard Bellenie , Graham Charles Bloomfield , Ian Bruce , Andrew James Culshaw , Edward Charles Hall , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
Inventor： Benjamin Richard Bellenie , Graham Charles Bloomfield , Ian Bruce , Andrew James Culshaw , Edward Charles Hall , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
IPC: C07D401/14 , C07D413/14 , C07D401/04 , C07D413/04 , C07D417/04 , C07D417/14 , C07D213/73 , C07D491/107 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/55
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
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Patent Agency Ranking
2.发明申请公开(公告)号：US20170042889A1
公开(公告)日：2017-02-16
申请号：US15303868
申请日：2014-04-24
Applicant: Benjamin Richard BELLENIE , Graham Charles BLOOMFIELD , Ian BRUCE , Andrew James CULSHAW , Edward Charles HALL , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
Inventor： Benjamin Richard BELLENIE , Graham Charles BLOOMFIELD , Ian BRUCE , Andrew James CULSHAW , Edward Charles HALL , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
IPC: A61K31/497 , C07D413/14 , C07D403/04 , C07D417/04 , C07D401/04 , C07D409/14 , C07D403/14 , C07D409/04 , A61K31/5377 , C07D405/04 , C07D417/14 , C07D401/14 , C07D413/04 , C07D405/14
CPC classification number: A61K31/497 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
Abstract translation: 本发明提供抑制PI 3激酶γ同种型活性的式（I）化合物，其可用于治疗由PI3激酶γ同种型激活介导的疾病。
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公开(公告)号：US09862711B2
公开(公告)日：2018-01-09
申请号：US15303890
申请日：2014-04-24
Applicant: Benjamin Richard Bellenie , Ian Bruce , Andrew James Culshaw , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
Inventor： Benjamin Richard Bellenie , Ian Bruce , Andrew James Culshaw , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
IPC: C07D417/04 , C07D401/04 , C07D403/04 , C07D409/04 , C07D405/14 , C07D403/14 , A61K31/5377 , A61K31/497
CPC classification number: C07D417/04 , A61K31/497 , A61K31/5377 , C07D401/04 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
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公开(公告)号：US20170029414A1
公开(公告)日：2017-02-02
申请号：US15303890
申请日：2014-04-24
Applicant: Benjamin Richard BELLENIE , Ian BRUCE , Andrew James CULSHAW , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
Inventor： Benjamin Richard BELLENIE , Ian BRUCE , Andrew James CULSHAW , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
IPC: C07D417/04 , C07D403/04 , C07D409/04 , A61K31/5377 , C07D401/04 , A61K31/497 , C07D405/14
CPC classification number: C07D417/04 , A61K31/497 , A61K31/5377 , C07D401/04 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
Abstract translation: 本发明提供抑制PI 3激酶γ同种型活性的式（I）化合物，其可用于治疗由PI3激酶γ同种型激活介导的疾病。
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公开(公告)号：US10004732B2
公开(公告)日：2018-06-26
申请号：US15303868
申请日：2014-04-24
Applicant: Benjamin Richard Bellenie , Graham Charles Bloomfield , Ian Bruce , Andrew James Culshaw , Edward Charles Hall , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
Inventor： Benjamin Richard Bellenie , Graham Charles Bloomfield , Ian Bruce , Andrew James Culshaw , Edward Charles Hall , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
IPC: C07D401/04 , C07D401/14 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , A61K31/497 , A61K31/5377 , C07D403/04
CPC classification number: A61K31/497 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
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6.发明申请公开(公告)号：US20170037032A1
公开(公告)日：2017-02-09
申请号：US15303879
申请日：2014-04-24
Applicant: Benjamin Richard BELLENIE , Graham Charles BLOOMFIELD , Ian BRUCE , Andrew James CULSHAW , Edward Charles HALL , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
Inventor： Benjamin Richard BELLENIE , Graham Charles BLOOMFIELD , Ian BRUCE , Andrew James CULSHAW , Edward Charles HALL , Gregory John HOLLINGWORTH , James NEEF , Matthew SPENDIFF , Simon James WATSON
IPC: C07D401/14 , C07D401/04 , A61K31/4439 , C07D417/04 , C07D413/04 , C07D417/14 , C07D491/107 , A61K31/5377 , A61K31/496 , A61K31/4545 , A61K31/55 , A61K31/444 , C07D413/14
CPC classification number: C07D401/14 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/55 , C07D213/73 , C07D401/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D491/107
Abstract: The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
Abstract translation: 本发明提供抑制PI 3激酶γ同种型活性的式（I）化合物，其可用于治疗由PI3激酶γ同种型激活介导的疾病。
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