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公开(公告)号:US07534885B2
公开(公告)日:2009-05-19
申请号:US10550718
申请日:2004-03-19
IPC分类号: C07D411/04 , A61K31/513 , A61K31/12
CPC分类号: C07D411/04
摘要: A process is disclosed for the stereo-selective preparation of emtricitabine, which allows the desired product to be obtained in good yield and without the use of chromatographic techniques. The process for the production of emtricitabine of the formula (Ia) is characterized by the formation and isolation of intermediate compounds of formula (XIa) in salified form. Emtricitabine is a known antiviral drug.
摘要翻译: 公开了用于立曲达因选择性制备恩曲他滨的方法,其允许以良好的产率获得所需的产物,而不使用色谱技术。 制备式(Ia)的恩曲他滨的方法的特征在于以成盐形式形成和分离式(XIa)的中间体化合物。 恩曲他滨是一种已知的抗病毒药物。
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公开(公告)号:US20090192310A1
公开(公告)日:2009-07-30
申请号:US12419050
申请日:2009-04-06
IPC分类号: C07D411/04
CPC分类号: C07D411/04
摘要: A novel process for preparing emtricitabine, and more particularly a process for preparing emtricitabine involving the formation and isolation of intermediate compounds in salified form, is described.
摘要翻译: 描述了一种制备恩曲他滨的新方法,更具体地涉及一种涉及以成盐形式形成和分离中间体化合物的恩曲他滨的制备方法。
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公开(公告)号:US20060189805A1
公开(公告)日:2006-08-24
申请号:US10550718
申请日:2004-03-19
IPC分类号: A61K31/513 , C07D409/02
CPC分类号: C07D411/04
摘要: A process is disclosed for the stereo-selective preparation of emtricitabine, which allows the desired product to be obtained in good yield and without the use of chromatographic techniques. The process for the production of emtricitabine of the formula (Ia) is characterized by the formation and isolation of intermediate compounds of formula (XIa) in salified form. Emtricitabine is a known antiviral drug.
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公开(公告)号:US07939660B2
公开(公告)日:2011-05-10
申请号:US12419050
申请日:2009-04-06
IPC分类号: C07D411/04 , C07D327/04 , A61K31/513 , A61P31/12
CPC分类号: C07D411/04
摘要: A novel process for preparing emtricitabine, and more particularly a process for preparing emtricitabine involving the formation and isolation of intermediate compounds in salified form, is described.
摘要翻译: 描述了一种制备恩曲他滨的新方法,更具体地涉及一种涉及以成盐形式形成和分离中间体化合物的恩曲他滨的制备方法。
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公开(公告)号:US20130071514A1
公开(公告)日:2013-03-21
申请号:US13641597
申请日:2011-04-18
IPC分类号: A23G4/12
CPC分类号: A23G4/12 , A23G4/062 , A23G4/20 , A23L27/72 , A23L27/82 , A23L33/15 , A23L33/155 , A23L33/20 , A23P10/30 , A23V2002/00 , A23V2250/032 , A23V2250/044 , A23V2250/242 , A23V2250/2482 , A23V2250/264 , A23V2250/6406 , A23V2250/6416 , A23V2250/642 , A23V2250/6422
摘要: The present invention relates to dietary formulations for the slow release of water-soluble active ingredients. Said formulations comprise a coating obtained by evaporation from vinyl polymer dispersions not containing emulsifiers. The formulations can be advantageously included in an edible composition, including confectionery products.
摘要翻译: 本发明涉及用于缓慢释放水溶性活性成分的膳食配方。 所述制剂包含通过从不含乳化剂的乙烯基聚合物分散体蒸发获得的涂层。 制剂可以有利地包括在可食用组合物中,包括糖食产品。
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