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公开(公告)号：US5047417A
公开(公告)日：1991-09-10
申请号：US354306
申请日：1989-05-19
Applicant: Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
Inventor： Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
IPC: C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/08 , C07D207/32 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D231/12 , C07D233/56 , C07D233/61 , C07D235/06 , C07D237/14 , C07D241/18 , C07D249/08 , C07D263/32 , C07D277/22 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07D521/00
CPC classification number: C07D207/08 , C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D231/12 , C07D233/56 , C07D235/06 , C07D237/14 , C07D241/18 , C07D249/08 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07C2101/08
Abstract: A butenoic or propenoic acid derivative having the following formula in which G is an aryl or a heterocyclic ring, R11 and R12 are hydrogen or an alkyl, X is sulfur or oxygen, R2 and R3 are hydrogen, an substituent such as an alkyl and J is pyridyl or phenyl having substituents and a heterocyclic ring may be formed between R2, R3 and J is provided here and is useful in the pharmacological field. ##STR1##
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公开(公告)号：US5607953A
公开(公告)日：1997-03-04
申请号：US347099
申请日：1994-11-23
Applicant: Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
Inventor： Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
IPC: C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/08 , C07D207/32 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D233/66 , C07D235/06 , C07D237/14 , C07D241/18 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07D521/00 , A61K31/335 , A61K31/34 , A61K31/38 , C07D213/63 , C07D319/14 , C07D403/06 , A64K31/40
CPC classification number: C07D207/08 , C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D231/12 , C07D233/56 , C07D235/06 , C07D237/14 , C07D241/18 , C07D249/08 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07C2101/08
Abstract: A butenoic or propenoic acid derivative having the following formula in which G is an aryl or a heterocyclic ring, R11 and R12 are hydroben or an alkyl, X is sulfur or oxygen, R2 and R3 are hydrogen, an substituent such as an alkyl and J is pyridyl or phenyl having substituents and a heterocyclic ring may be formed between R2, R3 and J is provided here and is useful in the pharmacological field. ##STR1##
Abstract translation: 具有下式的丁烯酸或丙烯酸衍生物，其中G是芳基或杂环，R11和R12是氢化或烷基，X是硫或氧，R2和R3是氢，取代基如烷基和J 在这里提供吡啶基或具有取代基的苯基和可以在R2，R3和J之间形成杂环，并且在药理学领域是有用的。
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公开(公告)号：US5177089A
公开(公告)日：1993-01-05
申请号：US557713
申请日：1990-07-25
Applicant: Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
Inventor： Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
IPC: C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/08 , C07D207/32 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D233/66 , C07D235/06 , C07D237/14 , C07D241/18 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07D521/00
CPC classification number: C07D207/08 , C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D231/12 , C07D233/56 , C07D235/06 , C07D237/14 , C07D241/18 , C07D249/08 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07C2101/08
Abstract: A butenoic or propenoic acid derivative having the following formula in which G is an aryl or a heterocyclic ring, R11 and R12 are hydroben or an alkyl, X is sulfur or oxygen, R2 and R3 are hydrogen, an substituent such as an alkyl and J is pyridyl or phenyl having substituents and a heterocyclic ring may be formed between R2, R3 and J is provided here and is useful in the pharmacological field. ##STR1##
Abstract translation: 具有下式的丁烯酸或丙烯酸衍生物，其中G是芳基或杂环，R11和R12是氢化或烷基，X是硫或氧，R2和R3是氢，取代基如烷基和J 在这里提供吡啶基或具有取代基的苯基和可以在R2，R3和J之间形成杂环，并且在药理学领域是有用的。 （二）
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公开(公告)号：US5382595A
公开(公告)日：1995-01-17
申请号：US959654
申请日：1992-10-13
Applicant: Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
Inventor： Norio Minami , Fumihiro Ozaki , Keiji Ishibashi , Yasuhiro Kabasawa , Megumi Ikemori , Toshiaki Ogawa , Takanori Kawamura
IPC: C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/08 , C07D207/32 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D233/66 , C07D235/06 , C07D237/14 , C07D241/18 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07D521/00 , A01N43/02 , C07C233/00
CPC classification number: C07D207/08 , C07C233/40 , C07C235/34 , C07C235/36 , C07C237/12 , C07C237/20 , C07C255/41 , C07C255/57 , C07C317/44 , C07C323/62 , C07D207/327 , C07D207/38 , C07D211/22 , C07D211/34 , C07D211/58 , C07D211/86 , C07D213/38 , C07D213/56 , C07D213/64 , C07D213/68 , C07D223/16 , C07D231/12 , C07D233/56 , C07D235/06 , C07D237/14 , C07D241/18 , C07D249/08 , C07D263/32 , C07D277/30 , C07D317/58 , C07D317/60 , C07D319/18 , C07D405/06 , C07D471/04 , C07C2101/08
Abstract: A butenoic or propenoic acid derivative having the following formula in which G is an aryl or a heterocyclic ring, R11 and R12 are hydroben or an alkyl, X is sulfur or oxygen, R2 and R3 are hydrogen, an substituent such as an alkyl and J is pyridyl or phenyl having substituents and a heterocyclic ring may be formed between R2, R3 and J is provided here and is useful in the pharmacological field. ##STR1##
Abstract translation: 具有下式的丁烯酸或丙烯酸衍生物，其中G是芳基或杂环，R11和R12是氢化或烷基，X是硫或氧，R2和R3是氢，取代基如烷基和J 在这里提供吡啶基或具有取代基的苯基和可以在R2，R3和J之间形成杂环，并且在药理学领域是有用的。
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