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    Plaster containing an active agent
    1.
    发明授权
    Plaster containing an active agent 失效
    含有活性剂的石膏

    公开(公告)号：US07045144B2

    公开(公告)日：2006-05-16

    申请号：US10239041

    申请日：2001-02-23

    申请人： Werner Schunk ,  Michael Bruder ,  Konrad Giessmann ,  Karl-Heinz Krause ,  Gerhard Merkmann

    发明人： Werner Schunk ,  Michael Bruder ,  Konrad Giessmann ,  Karl-Heinz Krause ,  Gerhard Merkmann

    IPC分类号： A61K9/00 ,  A61K9/70 ,  A61F13/00

    CPC分类号： A61K9/7038

    摘要： The invention relates to a plaster containing an active agent, comprising at least one cover membrane and an active membrane which is based on a skin-compatible matrix containing a molecular sieve which is loaded with at least one active agent. The molecular sieve/active agent adduct releases the active agent when the active membrane comes into contact with the skin, in conjunction with the transpired water of the skin. The inventive plaster is characterised in that the molecular sieve/active agent adduct also contains water of crystallisation, to the extent that the molecular sieve is partially hydrated compared to a sufficient basic molar quantity (m) of water of crystallisation, the molecular sieve with the reduced molar quantity (m′) of water of crystallisation being loaded with the active agent (Z, Z1, Z2) so that when the active membrane comes into contact with the skin, water is absorbed and the active agent is desorbed, whereupon the water of crystallisation content of the molecular sieve increases. The invention also relates to various suitable embodiments of the plaster containing an active agent and to an advantageous method for producing the inventive plaster containing an active agent.

    摘要翻译： 本发明涉及含有活性剂的石膏，其包括至少一个覆盖膜和活性膜，其基于含有分子筛的皮肤相容性基质，所述分子筛装载有至少一种活性剂。 当活性膜与皮肤接触时，分子筛/活性剂加合物与皮肤的蒸发水结合释放活性剂。 本发明的石膏的特征在于，分子筛/活性剂加合物还含有结晶水，在分子筛与足够的碱性摩尔数（m）结晶水相比分子筛部分水合的程度上，分子筛具有 降低了结晶活性剂（Z，Z 1，Z 2）的结晶水的摩尔量（m'），使得当活性膜与 皮肤，水被吸收并且活性剂被解吸，于是分子筛结晶含量的水增加。 本发明还涉及含有活性剂的石膏的各种合适的实施方案以及用于生产含有活性剂的本发明的石膏的有利方法。

    Rail arrangement
    4.
    发明授权
    Rail arrangement 失效
    铁路安排

    公开(公告)号：US06471139B1

    公开(公告)日：2002-10-29

    申请号：US09445840

    申请日：1999-12-14

    申请人： Michael Bruder ,  Michail Rabkin ,  Karl-Heinz Krause ,  Edgar Böhm ,  Gerhard Merkmann ,  Peter Schwob ,  Klaus Tübel

    发明人： Michael Bruder ,  Michail Rabkin ,  Karl-Heinz Krause ,  Edgar Böhm ,  Gerhard Merkmann ,  Peter Schwob ,  Klaus Tübel

    IPC分类号： E01B900

    CPC分类号： E01B9/681 ,  E01B9/62 ,  E01B9/68 ,  E01B9/683 ,  E01B9/686

    摘要： The invention relates to a rail arrangement for a rail superstucture such as a fixed railroad, comprising an elastic intermediate plate (3) which is located between the rail foot and a hard support (6) in the form of a concrete tie and has two through holes for the screws (7) to fasten the rails. For series mounting, which is the solution of choice, the elastic intermediate plate (3) is combined with an elastic intermediate layer (1) in such a way that the additional intermediate layer rests above the intermediate plate directly below the rail foot, whereby the intermediate layer (1) is separated from the intermediate plate (3) by a metal base plate (2) which serves to fasten the rail. According to the invention, the intermediate plate (3) consists of a single-piece vulcanisate made of a rubber mixture and has three structural zones related to a novel arrangement of protrusions (active surfaces) and recesses (inactive surfaces), whereby the inactive surfaces in the central zone are deeper than those in the two side zones. The invention also relates to other constructional features of the elastic intermediate plate (3).

    摘要翻译： 本发明涉及一种用于轨道结构（例如固定铁路）的轨道装置，其包括弹性中间板（3），该弹性中间板位于轨道脚与混凝土结扎形式的硬支撑（6）之间，并具有两个通过 用于螺钉（7）的孔用于固定导轨。 对于作为选择的解决方案的串联安装，弹性中间板（3）与弹性中间层（1）结合，使得附加中间层位于轨道脚下方的中间板的上方，由此 中间层（1）通过用于固定轨道的金属基板（2）与中间板（3）分离。 根据本发明，中间板（3）由橡胶混合物制成的单片硫化橡胶组成，并具有与突起（活性表面）和凹部（非活性表面）的新颖布置相关的三个结构区域，由此使非活性表面 在中部地区比两侧地区更深。 本发明还涉及弹性中间板（3）的其它结构特征。

    NMR probe for material analysis
    5.
    发明授权
    NMR probe for material analysis 有权
    NMR探针进行材料分析

    公开(公告)号：US07095230B2

    公开(公告)日：2006-08-22

    申请号：US10955416

    申请日：2004-09-30

    申请人： Bernhard Blümich ,  Michael Bruder ,  Martin Klein ,  Karl-Heinz Krause ,  Michael Rabkin ,  Jürgen Stangenberg ,  Vladimir Anferov ,  Sophia Anferova ,  Radu Fechete

    发明人： Bernhard Blümich ,  Michael Bruder ,  Martin Klein ,  Karl-Heinz Krause ,  Michael Rabkin ,  Jürgen Stangenberg ,  Vladimir Anferov ,  Sophia Anferova ,  Radu Fechete

    IPC分类号： G01V3/00

    CPC分类号： G01R33/3808 ,  G01N24/08 ,  G01R33/341 ,  G01R33/383

    摘要： In a unilateral NMR probe for the analysis of a material comprising at least one magnet for generating a constant time-invariant polarization field B0 in the material to be analyzed and current conductors forming a radio frequency oscillation circuit for generating a pulsed radio frequency magnetic excitation field B1 which is superimposed on the polarization field N0 in the material, the circuit conductors are so designed as to provide several adjacent excitation fields B0 with alternatingly oppositely oriented magnetic fields, whereby the current conductors generating each one of the excitation fields have a distance from each other which causes a certain penetration depth in the material to be analyzed and echoes received therefrom provide measurement values which are characteristic for the material being analyzed.

    摘要翻译： 在用于分析包括至少一个磁体的材料的单侧核磁探针中，用于在待分析的材料中产生恒定的时间不变极化场B 0 <0>和形成射频振荡电路的电流导体 产生叠加在材料中的偏振场N <0>上的脉冲射频磁激励场B 1，电路导体被设计成提供几个相邻的激励场 B <0>具有交替反向取向的磁场，由此产生每个激励场的电流导体彼此之间具有一定距离，这导致要分析的材料中的一定穿透深度，并且从其接收的回波提供 测量值是被分析材料的特征。