摘要:
The present invention relates conotoxin peptides that are analogs of the α-contoxin peptide RgIA. These conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain, such as neuropathic pain and inflammatory pain, inflammatory disorders, such as rheumatic diseases, and in the treatment of breast cancer.
摘要:
The invention relates to peptides (termed propeller peptides herein) and related peptides (termed peptides of the G12.2 family herein), about 60 to about 90 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which blocks the desensitization of AMPA-type ionotropic glutamate receptors (AMPARs).
摘要:
A combiner for optical beams includes a substrate overlaid by a multi-layer dielectric film stack. The substrate is a clear material and the dielectric film stack is a series of alternating layer of high and low refractive index. This gives the combiner relatively high reflectivity across UV wavelengths and relatively high transmissivity in the visible and longer wavelengths and allows visible light to pass through the combiner while UV light is reflected. At the same time dielectric film stack has minimal absorption and scatter. This means that the intensity of visible light maintains at least 90% of its intensity as it passes through combiner and UV light retains at least 90% of its intensity as it is reflected by combiner.
摘要:
A polymer substrate for recombinant protein purification is provided. A process for purifying recombinant proteins is also provided. In general, the present invention is directed to a chelating composition which may be used in a self-supported purification medium for recombinant protein purification. In another embodiment, a process for removal of transition metals from environmental waste is also provided.
摘要:
A computer system includes an object oriented framework that provides a set of application integration interfaces that support programmatic updating operations for maintaining locally stored copies of resources such as hypertext document pages from remote servers on a computer network. The updating operations continually check for updates to the data at the remote server and download updated versions of the resources to maintain concurrency of the locally stored copy. The updating operations are performed while a connection to the remote network is left idle, to maximize usage of on-line connection time. The updating operations also can be programmatically scheduled by a client program of the updating operations. The updating operations include updating the contents of a folder or directory in a local file system as specified in a file at a remote server on the network, and providing automatically updating and populating groups of sites or document pages organized by category.
摘要:
In a rotary valve controlling the inlet of fuel to, and exhaust of combustion products from, a combustion chamber, an improved seal is achieved by providing rigid upstanding lips in the valve housing about the opening of the housing into the combustion chamber, the lips sloping away from the combustion chamber opening and the housing being split diametrically for movement about a hinge pin to provide flexibility to the system and prevent clamping on the valve.
摘要:
Apparatus for removing the excess lubricant from a rotatably mounted cylindrical valve member for internal combustion engines, pumps and compressors includes a rigid scraper blade mounted within a housing and resiliently biased toward the surface of the cylindrical valve member. The lubricant is supplied copiously to the surface of the cylindrical member at one position and is removed as the cylindrical member rotates at a second position by the rigid blade which has an extremely small degree of flexibility so that it is deformed by an amount not greater than 1/3000 of the diameter of the cylindrical valve member when the blade and a recess in the cylindrical valve member are in register.
摘要:
The present invention relates conotoxin peptides that are analogs of the α-conotoxin peptide RgIA. These conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain, such as neuropathic pain and inflammatory pain, inflammatory disorders, such as rheumatic diseases, and in the treatment of breast cancer.
摘要:
A computer system includes an object oriented framework that provides a set of application integration interfaces that support programmatic updating operations for maintaining locally stored copies of resources such as hypertext document pages from remote servers on a computer network. The updating operations continually check for updates to the data at the remote server and download updated versions of the resources to maintain concurrency of the locally stored copy. The updating operations are performed while a connection to the remote network is left idle, to maximize usage of on-line connection time. The updating operations also can be programmatically scheduled by a client program of the updating operations. The updating operations include updating the contents of a folder or directory in a local file system as specified in a file at a remote server on the network, and providing automatically updating and populating groups of sites or document pages organized by category.
摘要:
A computer system includes an object oriented framework that provides a set of application integration interfaces that support programmatic updating operations for maintaining locally stored copies of resources such as hypertext document pages from remote servers on a computer network. The updating operations continually check for updates to the data at the remote server and download updated versions of the resources to maintain concurrency of the locally stored copy. The updating operations are performed while a connection to the remote network is left idle, to maximize usage of on-line connection time. The updating operations also can be programmatically scheduled by a client program of the updating operations. The updating operations include updating the contents of a folder or directory in a local file system as specified in a file at a remote server on the network, and providing automatically updating and populating groups of sites or document pages organized by category.