公开(公告)号：US20170119362A1

公开(公告)日：2017-05-04

申请号：US15201950

申请日：2016-07-05

申请人： Michael R. Afremov

发明人： Michael R. Afremov

IPC分类号： A61B17/00 ,  A61B17/12

CPC分类号： A61B17/0057 ,  A61B17/12113 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12181 ,  A61B2017/00004 ,  A61B2017/00575 ,  A61B2017/00606 ,  A61B2017/00623

摘要： The present invention is directed towards implantable, inflatable, bioabsorbable medical prostheses. In particular, the present invention relates to an implantable, inflatable, bioabsorbable method and device for occluding septal defects such as an atrial septal defect. A double button shaped device is contained in a catheter to allow for easy positioning and re-positioning of the apparatus to ensure proper placement and deployment. The device is charged with a filling solution so that it temporarily stabilizes the defect for a period of time typically varying from weeks to a year while it provides a structure to support natural tissue growth. The device is eventually replaced by natural tissue as it degrades and is absorbed or eliminated from the body by natural processes.

公开(公告)号：US20090093870A1

公开(公告)日：2009-04-09

申请号：US11867790

申请日：2007-10-05

申请人： Adolfo Menendez ,  Paul W. Schmokel ,  Eilaz P. Babaev ,  Scott R. Banaszewski ,  Michael R. Afremov

发明人： Adolfo Menendez ,  Paul W. Schmokel ,  Eilaz P. Babaev ,  Scott R. Banaszewski ,  Michael R. Afremov

IPC分类号： A61F2/06 ,  B05D3/02

CPC分类号： B05D1/002 ,  A61F2/82 ,  A61M2025/1031 ,  B05B13/0228 ,  B05D1/02

摘要： The present invention is directed towards the holding of medical devices during manufacture to enable the application of therapeutic and/or protective coatings. More specifically, the present invention provides medical device holders that securely retain stents and other medical devices during the application of a coating while minimizing compressive and tensile forces applied to the stents. The invention avoids disruptions to coating quality due to holder blockage during coating deposition. The invention discloses an improved device containing a mandrel and frame that may improve coating uniformity by eliminating shadowing from the frame of the medical device holder when applying coatings to stents and other medical devices.

摘要翻译： 本发明涉及在制造过程中保持医疗装置以能够施用治疗和/或保护性涂层。 更具体地，本发明提供了在施加涂层期间可靠地保持支架和其他医疗装置的医疗装置保持器，同时最小化施加到支架的压缩和拉伸力。 本发明避免了在涂布沉积期间由于夹持器堵塞而导致的涂层质量的破坏。 本发明公开了一种包含心轴和框架的改进装置，当将支架和其它医疗装置涂覆时，可以通过消除从医疗装置支架的框架上的遮蔽来提高涂层的均匀性。

公开(公告)号：US06241678B1

公开(公告)日：2001-06-05

申请号：US09137949

申请日：1998-08-21

申请人： Michael R. Afremov ,  Kurt Amplatz

发明人： Michael R. Afremov ,  Kurt Amplatz

IPC分类号： A61B502

CPC分类号： A61M25/10 ,  A61B5/1076

摘要： A sizing catheter and method of measuring a preselected internal opening within a patient to provide a rapid and precise determination of a stretched diameter of the preselected internal opening. The sizing catheter includes a dilation balloon constructed of a thin expandable plastic which is inflatable and is utilized to determine a size of the preselected opening. The dilation balloon is inflated to an inflation threshold, wherein the dilation balloon deforms about the preselected opening and the size of the dilation balloon adjacent the preselected opening approximates a stretched diameter of the preselected opening. The sizing catheter and method may be utilized to determine an appropriate sized occluding device to thereby occlude the preselected opening.

摘要翻译： 尺寸导管和测量患者内的预选内部开口的方法，以提供对预选内部开口的拉伸直径的快速和精确的确定。 定径导管包括由可膨胀的薄的可膨胀塑料构成的膨胀气囊，并且用于确定预选开口的尺寸。 膨胀气囊膨胀到充气阈值，其中扩张气囊围绕预选开口变形，并且与预选开口相邻的扩张球囊的尺寸近似于预选开口的拉伸直径。 定径导管和方法可用于确定适当大小的闭塞装置，从而封闭预选的开口。

公开(公告)号：US20090090299A1

公开(公告)日：2009-04-09

申请号：US11867818

申请日：2007-10-05

申请人： Adolfo Menendez ,  Paul W. Schmokel ,  Eilaz P. Babaev ,  Scott R. Banaszewski ,  Michael R. Afremov

发明人： Adolfo Menendez ,  Paul W. Schmokel ,  Eilaz P. Babaev ,  Scott R. Banaszewski ,  Michael R. Afremov

IPC分类号： B05C13/02

CPC分类号： B05B13/0442 ,  B05D1/002 ,  B05D1/02

摘要： The present invention is directed towards the holding of medical devices during manufacture to enable the application of therapeutic and/or protective coatings. More specifically, the present invention provides medical device holders that securely retain stents and other medical devices during the application of a coating while minimizing compressive and tensile forces applied to the stents. The invention avoids disruptions to coating quality due to holder blockage during coating deposition. The invention discloses an improved device containing a mandrel and frame that may improve coating uniformity by eliminating shadowing from the frame of the medical device holder when applying coatings to stents and other medical devices.

摘要翻译： 本发明涉及在制造过程中保持医疗装置以能够施用治疗和/或保护性涂层。 更具体地，本发明提供了在施加涂层期间可靠地保持支架和其他医疗装置的医疗装置保持器，同时最小化施加到支架的压缩和拉伸力。 本发明避免了在涂布沉积期间由于夹持器堵塞而导致的涂层质量的破坏。 本发明公开了一种包含心轴和框架的改进装置，当将支架和其它医疗装置涂覆时，可以通过消除从医疗装置支架的框架上的遮蔽来提高涂层的均匀性。

公开(公告)号：US08689728B2

公开(公告)日：2014-04-08

申请号：US11867818

申请日：2007-10-05

申请人： Menendez Adolfo ,  Paul W Schmokel ,  Eilaz P Babaev ,  Scott R Banaszewski ,  Michael R Afremov

发明人： Menendez Adolfo ,  Paul W Schmokel ,  Eilaz P Babaev ,  Scott R Banaszewski ,  Michael R Afremov

IPC分类号： B05C13/00 ,  B05D3/00

CPC分类号： B05B13/0442 ,  B05D1/002 ,  B05D1/02

摘要： The present invention is directed towards the holding of medical devices during manufacture to enable the application of therapeutic and/or protective coatings. More specifically, the present invention provides medical device holders that securely retain stents and other medical devices during the application of a coating while minimizing compressive and tensile forces applied to the stents. The invention avoids disruptions to coating quality due to holder blockage during coating deposition. The invention discloses an improved device containing a mandrel and frame that may improve coating uniformity by eliminating shadowing from the frame of the medical device holder when applying coatings to stents and other medical devices.

摘要翻译： 本发明涉及在制造过程中保持医疗装置以能够施用治疗和/或保护性涂层。 更具体地，本发明提供了在施加涂层期间可靠地保持支架和其他医疗装置的医疗装置保持器，同时最小化施加到支架的压缩和拉伸力。 本发明避免了在涂布沉积期间由于夹持器堵塞而导致的涂层质量的破坏。 本发明公开了一种包含心轴和框架的改进装置，当将支架和其它医疗装置涂覆时，可以通过消除从医疗装置支架的框架上的遮蔽来提高涂层的均匀性。

公开(公告)号：US5944738A

公开(公告)日：1999-08-31

申请号：US19620

申请日：1998-02-06

申请人： Kurt Amplatz ,  Michael R. Afremov

发明人： Kurt Amplatz ,  Michael R. Afremov

IPC分类号： A61B17/12 ,  A61B17/00 ,  A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00606

摘要： A collapsible medical device and associated method for occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from a shape memory metal fabric. The device may be used, for example, to non-surgically treat a patient having a Patent Foramen Ovale (PFO) and resulting paradoxical cerebral emboli. The device is preferably made from a continuous tubular metal fabric and includes two outer occluding portions and a resilient central, spring-like interconnecting member. The metal fabric may be heat treated within a mold in order to substantially set a desired shape of the device. The medical device includes a fastener for attaching to the end of a guide wire or delivery catheter. The medical device having the desired relaxed shape may be collapsed and delivered through a catheter or the like for deployment in a desired channel or opening in a patient's body.

摘要翻译： 一种用于阻塞例如身体器官中的异常开口的可折叠的医疗装置和相关联的方法，其中所述医疗装置由形状记忆金属织物成形。 该装置可以用于例如非手术治疗具有专利孔眼（PFO）和产生的矛盾性脑栓塞的患者。 该装置优选地由连续的管状金属织物制成，并且包括两个外部阻塞部分和弹性中心的弹簧状互连构件。 金属织物可以在模具内进行热处理，以便基本上设定所需装置的形状。 医疗装置包括用于附接到导丝或输送导管的端部的紧固件。 具有所需松弛形状的医疗装置可以通过导管等折叠并输送，以展开在患者身体中的期望的通道或开口中。