公开(公告)号：US5736325A

公开(公告)日：1998-04-07

申请号：US299187

申请日：1994-08-31

申请人： Paul Manowitz ,  Ronald D. Poretz ,  David Park ,  Michael Ricketts

发明人： Paul Manowitz ,  Ronald D. Poretz ,  David Park ,  Michael Ricketts

IPC分类号： C07K16/40 ,  C12N9/16 ,  C12Q1/68 ,  G01N33/573 ,  C07H21/04 ,  C12N15/00

CPC分类号： C12N9/16 ,  C07K16/40 ,  C12Q1/6883 ,  G01N33/573 ,  C12Q1/683 ,  C12Q2600/156 ,  C12Q2600/172 ,  Y10S435/81 ,  Y10S435/975

摘要： The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).

摘要翻译： 本发明涉及用于诊断酒精中毒易感性的方法或基于个体中遗传标记检测的酒精中毒的病理作用。 本发明一般涉及用于检测人类中芳基硫酸酯酶A（ASA）假性缺陷（PD）突变的存在的方法和相关组合物和试剂盒。 惊奇地发现这些突变的检测是对酒精中毒易感性和/或对酒精病理作用的易感性的强指示剂，以及评估异染色性脑白质营养不良（MLD）可能性的重要标志物。

公开(公告)号：US20070190930A1

公开(公告)日：2007-08-16

申请号：US11556449

申请日：2006-11-03

申请人： Stephen C. Fuller ,  Jon Michael Ricketts ,  James J. Langley

发明人： Stephen C. Fuller ,  Jon Michael Ricketts ,  James J. Langley

IPC分类号： H04H7/00

CPC分类号： H04H60/51 ,  H04H20/57 ,  H04H20/74

摘要： The present invention is directed to an apparatus and method for providing access to educational and training services to truck drivers in the cabs of their trucks. The apparatus includes an in-vehicle communications system that combines Wi-Fi, cellular, IP radio and satellite communications systems for sending data to and from the cab. The method includes steps of accessing educational course information from an educational institution computer system, selecting a wireless communication system for communicating with the in-vehicle communication system, transmitting the educational course information via the wireless communication system, receiving the educational course information at the in-vehicle communication system, and presenting the educational course information to an occupant of the transport vehicle using a display device associated with the in-vehicle communication system. In one embodiment, the geographic location of the transport vehicle is determined, and the wireless communication system is selected based at least in part on the geographic location.

摘要翻译： 本发明涉及一种用于向卡车驾驶室内的卡车司机提供教育和训练服务的装置和方法。 该装置包括车载通信系统，其结合Wi-Fi，蜂窝，IP无线电和卫星通信系统，用于向驾驶室发送数据和从驾驶室发送数据。 该方法包括从教育机构计算机系统访问教育课程信息的步骤，选择用于与车载通信系统通信的无线通信系统，经由无线通信系统发送教育课程信息，接收教育课程信息 - 车辆通信系统，并且使用与车载通信系统相关联的显示装置将教育课程信息呈现给运输车辆的乘客。 在一个实施例中，确定运输车辆的地理位置，并且至少部分地基于地理位置选择无线通信系统。

公开(公告)号：US5970633A

公开(公告)日：1999-10-26

申请号：US186808

申请日：1998-11-05

申请人： Raymond K. Jones ,  Mark A. Jones ,  Michael Ricketts

发明人： Raymond K. Jones ,  Mark A. Jones ,  Michael Ricketts

IPC分类号： A43B3/00 ,  A43B5/16 ,  A43B5/18 ,  A43B23/00 ,  A43B3/16

CPC分类号： A43B3/0031 ,  A43B1/0036 ,  A43B5/1666 ,  A43B5/18

摘要： An overshoe construction (10) for athletic shoes (100) wherein the construction (10) includes a cover member (20) dimensioned to overlie the upper portion of the athletic shoe (100) and provided with an accessory unit (12) which includes a pocket member (30) and at least one strap member (32) adapted to releasably engage a miniature flashlight (50).

摘要翻译： 一种用于运动鞋（100）的套鞋结构（10），其中，所述构造（10）包括覆盖所述运动鞋（100）的上部并且设置有附件单元（12）的盖构件（20），所述附件单元包括 袋构件（30）和适于可释放地接合微型手电筒（50）的至少一个带构件（32）。