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    Whole genome mapping by DNA sequencing with linked-paired-end library
    1.
    发明授权
    Whole genome mapping by DNA sequencing with linked-paired-end library 有权

    公开(公告)号：US09758780B2

    公开(公告)日：2017-09-12

    申请号：US14728223

    申请日：2015-06-02

    申请人： Ming Xiao ,  Justin Sibert

    发明人： Ming Xiao ,  Justin Sibert

    IPC分类号： C12Q1/68 ,  C12N15/10 ,  C07H21/02 ,  G06F19/18

    CPC分类号： C12N15/1068 ,  C12Q1/6806 ,  G06F19/18

    摘要： The present invention relates to innovative means of generating sequence-linked DNA fragments and subsequent uses of such linked DNA fragments for de novo haplotype-resolved whole genome mapping and massively parallel sequencing. In various embodiments described herein, the methods of the invention relate to methods of generating paired-end nucleic acid fragment sharing common linker nucleic acid sequences using a nicking endonuclease, a T7 endonuclease, a restriction enzyme, or a transposase, methods of analyzing the nucleotides sequences from the linked-paired-end sequenced fragments, and methods of de novo whole genome mapping. Thus, the methods of this invention allow establishing sequence contiguity across the whole genome, and achieving high-quality, low-cost de novo assembly of complex genomes.

    Whole Genome Mapping by DNA Sequencing With Linked-Paired-End Library
    2.
    发明申请
    Whole Genome Mapping by DNA Sequencing With Linked-Paired-End Library 有权
    通过DNA测序的全基因组映射与链接配对文库

    公开(公告)号：US20150344873A1

    公开(公告)日：2015-12-03

    申请号：US14728223

    申请日：2015-06-02

    申请人： Ming Xiao ,  Justin Sibert

    发明人： Ming Xiao ,  Justin Sibert

    IPC分类号： C12N15/10 ,  G06F19/18 ,  C12Q1/68

    CPC分类号： C12N15/1068 ,  C12Q1/6806 ,  G06F19/18

    摘要： The present invention relates to innovative means of generating sequence-linked DNA fragments and subsequent uses of such linked DNA fragments for de novo haplotype-resolved whole genome mapping and massively parallel sequencing. In various embodiments described herein, the methods of the invention relate to methods of generating paired-end nucleic acid fragment sharing common linker nucleic acid sequences using a nicking endonuclease, a T7 endonuclease, a restriction enzyme, or a transposase, methods of analyzing the nucleotides sequences from the linked-paired-end sequenced fragments, and methods of de novo whole genome mapping. Thus, the methods of this invention allow establishing sequence contiguity across the whole genome, and achieving high-quality, low-cost de novo assembly of complex genomes.

    摘要翻译： 本发明涉及产生序列连接的DNA片段的创新方法以及随后使用这种连接的DNA片段进行从头单体型解析的全基因组测绘和大规模并行测序。 在本文描述的各种实施方案中，本发明的方法涉及使用切口内切核酸酶，T7内切核酸酶，限制酶或转座酶产生分支共同连接体核酸序列的配对末端核酸片段的方法，分析核苷酸的方法 来自连锁配对末端测序片段的序列，以及从头整体基因组测绘的方法。 因此，本发明的方法允许跨整个基因组建立序列连续性，并实现复杂基因组的高品质，低成本的从头装配。

    Electronic device with airflow guiding duct
    3.
    发明授权
    Electronic device with airflow guiding duct 失效
    带导气管的电子设备

    公开(公告)号：US08625276B2

    公开(公告)日：2014-01-07

    申请号：US13219858

    申请日：2011-08-29

    申请人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao

    发明人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao

    IPC分类号： H05K7/20

    CPC分类号： G06F1/20

    摘要： An electronic device includes an enclosure, and an airflow guiding duct. The enclosure includes a bottom panel. The airflow guiding duct is pivotably mounted to the enclosure. The airflow guiding duct includes a positioning portion. The bottom panel defines a sliding slot. A positioning opening is defined in the bottom panel communicating with the sliding slot. The positioning portion is used for being driven to slide along the sliding slot to move into the positioning opening when the airflow guiding duct is rotated.

    摘要翻译： 电子设备包括外壳和气流引导导管。 外壳包括底板。 气流引导管可枢转地安装在外壳上。 气流引导管道包括定位部分。 底板限定滑动槽。 定位开口限定在与滑槽连通的底板中。 当气流引导管旋转时，定位部分用于被驱动以沿着滑动槽滑动以移动到定位开口中。

    Mounting apparatus with rotating member for retaining and buffering data storage device
    4.
    发明授权
    Mounting apparatus with rotating member for retaining and buffering data storage device 失效
    具有用于保持和缓冲数据存储装置的旋转构件的安装装置

    公开(公告)号：US08576558B2

    公开(公告)日：2013-11-05

    申请号：US13222673

    申请日：2011-08-31

    申请人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao

    发明人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao

    IPC分类号： H05K7/00

    CPC分类号： G06F1/187 ,  F16B5/0635

    摘要： A mounting apparatus for mounting a data storage device includes a sliding member, a drive bracket, and a rotating member. The drive bracket includes a first side plate. A sliding groove is defined in the first side plate. The sliding member is received in the sliding groove. The rotating member is pivotally mounted to the first side plate. A curled piece and an arm are located on opposite ends of the rotating member. The arm defines a restricting room. The rotating member is adapted to rotate on the first side plate between a first position and a second position. In the first position, the curled piece abuts the first side plate and is elastically deformed by the first side plate, and the sliding member is disengaged from the restricting room. In the second position, the curled piece is released, and the restricting room receives and restricts the sliding member therein.

    摘要翻译： 用于安装数据存储装置的安装装置包括滑动构件，驱动支架和旋转构件。 驱动支架包括第一侧板。 在第一侧板中限定滑动槽。 滑动构件容纳在滑动槽中。 旋转构件枢转地安装到第一侧板。 卷曲片和臂位于旋转构件的相对端。 手臂定义了限制室。 旋转构件适于在第一位置和第二位置之间在第一侧板上旋转。 在第一位置，卷曲件邻接第一侧板并且由第一侧板弹性变形，并且滑动构件从限制室脱离。 在第二位置，卷曲片被释放，限制室接收并限制滑动构件。

    Mounting apparatus for data storage device
    5.
    发明授权
    Mounting apparatus for data storage device 失效
    数据存储装置用安装装置

    公开(公告)号：US08434726B2

    公开(公告)日：2013-05-07

    申请号：US13272538

    申请日：2011-10-13

    申请人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao ,  Hai-Qing Zhu

    发明人： Yun-Lung Chen ,  Liang-Chin Wang ,  Jian Hu ,  Yu-Ming Xiao ,  Hai-Qing Zhu

    IPC分类号： G06F1/16

    CPC分类号： G06F1/187

    摘要： A mounting apparatus for mounting a data storage device on a bracket includes a locating member fixed on the bracket. The bracket includes a sidewall defining a first through hole and a second through hole at a sidewall back. The sidewall defines a first fixing slot and a second fixing slot at a sidewall front. The data storage device defines a fixing hole. A fixing portion is located on a first end of the locating member corresponds to the first through hole, the second through hole and the fixing hole. A locking portion is located on a second end of the locating member corresponds to the first fixing slot and the second fixing slot. The data storage device is fixed on a first position and a second position of the bracket.

    摘要翻译： 用于将数据存储装置安装在支架上的安装装置包括固定在支架上的定位构件。 支架包括限定第一通孔的侧壁和在侧壁背面的第二通孔。 侧壁在侧壁前侧限定第一固定槽和第二固定槽。 数据存储装置定义一个固定孔。 固定部分位于定位构件的第一端上，对应于第一通孔，第二通孔和固定孔。 锁定部分位于定位构件的第二端上，对应于第一固定槽和第二固定槽。 数据存储装置固定在支架的第一位置和第二位置。

    MOUNTING APPARATUS ASSEMBLY
    6.
    发明申请
    MOUNTING APPARATUS ASSEMBLY 有权
    安装装置

    公开(公告)号：US20120307443A1

    公开(公告)日：2012-12-06

    申请号：US13304754

    申请日：2011-11-28

    申请人： YUN-LUNG CHEN ,  JIAN HU ,  YU-MING XIAO ,  NIAN-YUAN YANG ,  LIANG-CHIN WANG

    发明人： YUN-LUNG CHEN ,  JIAN HU ,  YU-MING XIAO ,  NIAN-YUAN YANG ,  LIANG-CHIN WANG

    IPC分类号： G06F1/16

    CPC分类号： G06F1/187

    摘要： A mounting apparatus assembly includes a data storage bracket, a computer enclosure, a mounting member fixed on the data storage bracket and a guiding rail fixed on the computer enclosure. A mounting portion is installed on the mounting member. A plurality of mounting slots is located on the guiding rail. When the bracket rotates relative to the computer enclosure, the mounting portion moves along the guiding rail and engages with the plurality of mounting slots, and the data storage bracket is installed at a required position on the computer enclosure.

    摘要翻译： 安装装置组件包括数据存储支架，计算机外壳，固定在数据存储支架上的安装构件和固定在计算机机壳上的导轨。 安装部安装在安装部件上。 多个安装槽位于导轨上。 当支架相对于计算机外壳旋转时，安装部分沿着导轨移动并与多个安装槽接合，并且数据存储支架安装在计算机外壳上的所需位置。

    MOUNTING APPARATUS FOR DATA STORAGE DEVICE
    7.
    发明申请
    MOUNTING APPARATUS FOR DATA STORAGE DEVICE 失效
    数据存储设备的安装设备

    公开(公告)号：US20120305720A1

    公开(公告)日：2012-12-06

    申请号：US13272538

    申请日：2011-10-13

    申请人： YUN-LUNG CHEN ,  LIANG-CHIN WANG ,  JIAN HU ,  YU-MING XIAO ,  HAI-QING ZHU

    发明人： YUN-LUNG CHEN ,  LIANG-CHIN WANG ,  JIAN HU ,  YU-MING XIAO ,  HAI-QING ZHU

    IPC分类号： H05K7/00

    CPC分类号： G06F1/187

    摘要： A mounting apparatus for mounting a data storage device on a bracket includes a locating member fixed on the bracket. The bracket includes a sidewall defining a first through hole and a second through hole at a sidewall back. The sidewall defines a first fixing slot and a second fixing slot at a sidewall front. The data storage device defines a fixing hole. A fixing portion is located on a first end of the locating member corresponds to the first through hole, the second through hole and the fixing hole. A locking portion is located on a second end of the locating member corresponds to the first fixing slot and the second fixing slot. The data storage device is fixed on a first position and a second position of the bracket.

    摘要翻译： 用于将数据存储装置安装在支架上的安装装置包括固定在支架上的定位构件。 支架包括限定第一通孔的侧壁和在侧壁背面的第二通孔。 侧壁在侧壁前侧限定第一固定槽和第二固定槽。 数据存储装置定义一个固定孔。 固定部分位于定位构件的第一端上，对应于第一通孔，第二通孔和固定孔。 锁定部分位于定位构件的第二端上，对应于第一固定槽和第二固定槽。 数据存储装置固定在支架的第一位置和第二位置。

    ELECTRONIC DEVICE ENCLOSURE FOR RECEIVING STORAGE DEVICE
    8.
    发明申请
    ELECTRONIC DEVICE ENCLOSURE FOR RECEIVING STORAGE DEVICE 审中-公开
    用于接收存储设备的电子设备外壳

    公开(公告)号：US20120217856A1

    公开(公告)日：2012-08-30

    申请号：US13326413

    申请日：2011-12-15

    申请人： YUN-LUNG CHEN ,  LIANG-CHIN WANG ,  JIAN HU ,  YU-MING XIAO ,  HAI-QING ZHU

    发明人： YUN-LUNG CHEN ,  LIANG-CHIN WANG ,  JIAN HU ,  YU-MING XIAO ,  HAI-QING ZHU

    IPC分类号： H05K5/02

    CPC分类号： G06F1/187

    摘要： An electronic device with a storage device enclosure is disclosed. The electronic device enclosure comprises a chassis comprising a bottom plate and a side plate substantially perpendicular to the bottom plate; a securing member attached to the side plate and comprising a plurality of positioning slots; a bracket rotatably attached to the side plate about a pivoting axis substantially parallel to the bottom plate relative to the chassis; the bracket comprising a side panel substantially perpendicular to the side plate; a blocking portion located on the side panel, and the blocking portion being elastic and engaged in one of the plurality of positioning slots.

    摘要翻译： 公开了一种具有存储设备外壳的电子设备。 电子设备外壳包括底盘，底盘包括底板和基本上垂直于底板的侧板; 固定构件，其附接到所述侧板并且包括多个定位槽; 围绕基本上平行于底板的枢转轴线相对于底盘可旋转地附接到侧板的支架; 所述支架包括基本上垂直于所述侧板的侧板; 位于所述侧板上的阻挡部分，并且所述阻挡部分具有弹性并且接合在所述多个定位槽之一中。