Method for treatment in gene therapy and use of guanine derivative therefor
    2.
    发明授权
    Method for treatment in gene therapy and use of guanine derivative therefor 有权
    基因治疗方法及鸟嘌呤衍生物的应用

    公开(公告)号:US06331528B1

    公开(公告)日:2001-12-18

    申请号:US09557327

    申请日:2000-04-25

    申请人: Nobukazu Ono

    发明人: Nobukazu Ono

    IPC分类号: A61K3170

    摘要: The present invention relates to a method for inhibiting cell growth whereby a thymidine kinase gene is introduced and expressed in a cell followed by administering a (−)-9-[1,S,2′R-bis(hydroxymethyl)cyclopropan-1′-yl]methylguanine in an amount sufficient to inhibit cell growth.

    摘要翻译: 本发明涉及抑制细胞生长的方法,其中引入胸腺嘧啶激酶基因并在细胞中表达,然后施用( - ) - 9- [1,S,2'R-双(羟甲基)环丙烷-1' - 基]甲基鸟嘌呤,其量足以抑制细胞生长。