Production of Glucosinolates from Agricultural By-Products & Waste
    3.
    发明申请
    Production of Glucosinolates from Agricultural By-Products & Waste 审中-公开
    从农副产品和废物生产硫代葡萄糖苷

    公开(公告)号:US20080311276A1

    公开(公告)日:2008-12-18

    申请号:US11761883

    申请日:2007-06-12

    IPC分类号: A23L1/28

    CPC分类号: C07H15/14 C07H1/08

    摘要: The present invention relates to a process for producing glucosinolates, particularly glucoraphanin, from cruciferous plants. More particularly, a method is provided for producing glucosinolates from agricultural by-products and waste. The general method comprises providing a mixture of glucosinolate-containing plant material and liquid, heating the mixture to inactivate enzymes in the plant material, contacting the heat inactivated mixture with an anion exchange membrane whereby at least a portion of the glucosinolates are extracted from the liquid and absorbed onto the anion exchange membrane, and releasing the glucosinolates from the anion exchange membrane. Preferably, the extraction and release steps are repeated at least once. The glucosinolates produce by the method of the invention may be incorporated into a variety of food products, pharmaceuticals, and health supplements.

    摘要翻译: 本发明涉及一种从十字花科植物生产硫代葡萄糖苷,特别是葡糖多糖的方法。 更具体地,提供了用于从农副产物和废物生产硫代葡萄糖苷的方法。 通常的方法包括提供含有硫代葡萄糖苷的植物材料和液体的混合物,加热混合物以灭活植物材料中的酶,使热灭活的混合物与阴离子交换膜接触,由此至少一部分硫代葡萄糖苷从液体中提取 并吸收到阴离子交换膜上,并从阴离子交换膜中释放硫代葡萄糖苷。 优选地,提取和释放步骤重复至少一次。 通过本发明的方法生产的硫代葡萄糖苷可以掺入各种食品,药物和保健品中。

    Enteric-Coated Glucosinolates And Beta-Thioglucosidases
    4.
    发明申请
    Enteric-Coated Glucosinolates And Beta-Thioglucosidases 审中-公开
    肠溶包被的硫代葡萄糖苷和β-硫葡糖苷酶

    公开(公告)号:US20080311192A1

    公开(公告)日:2008-12-18

    申请号:US11761843

    申请日:2007-06-12

    IPC分类号: A61K9/14 A61K38/47 A61K9/48

    摘要: The present invention relates to a particulate composition comprising enteric-coated glucosinolate and beta-thioglucosidase particles. The present invention further provides a method of converting glucosinolate to isothiocyanate in the small intestine comprising orally administering to a subject an enteric-coated chemoprotectant precursor composition comprising enteric-coated glucosinolate and beta-thioglucosinodase particles. In another aspect, uncoated glucosinolate and beta-thioglucosinodase particles may be provided in an enteric-coated capsule. Preferably, the glucosinolate is glucoraphanin and the beta-thioglucosidase is myrosinase. The enteric coating targets the compound for release in the small intestine where beta-thioglucosinodase enzyme converts glucosinolate to chemoprotectant isothiocyanate.

    摘要翻译: 本发明涉及包含肠溶包衣的硫代葡萄糖苷苷和β-硫代葡糖苷酶颗粒的颗粒组合物。 本发明还提供了一种在小肠中将芥子油苷转化成异硫氰酸酯的方法,其包括向受试者口服施用包含肠溶包衣的硫代葡萄糖苷和β-硫代葡萄糖苷糖苷酶颗粒的肠溶衣化学保护剂前体组合物。 在另一方面,可以在肠溶衣胶囊中提供未包衣的硫代葡萄糖苷和β-硫代葡糖苷调节酶颗粒。 优选地,硫代葡萄糖苷是葡萄糖甙元,β-硫代葡萄糖苷酶是黑芥子酶。 肠溶衣靶向化合物在小肠中释放,其中β-硫代葡糖苷异酶将芥子油苷转化成化学保护剂异硫氰酸酯。

    Method of enriching glucoraphanin in radish seed preparations
    8.
    发明授权
    Method of enriching glucoraphanin in radish seed preparations 失效
    萝卜种子制剂中富含萝卜素的方法

    公开(公告)号:US07371419B1

    公开(公告)日:2008-05-13

    申请号:US11617934

    申请日:2006-12-29

    IPC分类号: A61K36/00

    CPC分类号: A61K36/31

    摘要: The present invention relates to chemoprotective compounds and a method for producing chemoprotectant precursor-enriched extracts from crucifer seeds. More particularly, a method is provided for producing chemoprotectant precursor-enriched extracts from radish seeds with increased ratio of glucoraphanin to glucoraphenin. The general method comprises preparing an aqueous extract, contacting the aqueous extract with an adsorbent, removing the adsorbent to obtain a glucosinolate-containing extract, drying the glucosinolate-containing extract to obtain a dried glucosinolate-containing extract, mixing at least a portion of the dried glucosinolate-containing extract with a solvent to form a glucosinolate-containing suspension, clarifying the glucosinolate-containing suspension, contacting the glucosinolate-containing suspension with a catalyst, and introducing hydrogen for a time sufficient to obtain a chemoprotectant precursor-enriched extract. The chemoprotectant precursor-enriched extracts may be further processed to form a chemoprotectant precursor-enriched isolate or processed for use in various applications, including incorporation into a variety of food products and pharmaceuticals.

    摘要翻译: 本发明涉及化学保护性化合物和从十字花科植物种子生产富含化学保护素前体的提取物的方法。 更具体地,提供了一种用于从萝卜种子生产富含富含化学保护素前体的提取物的方法,其中葡萄糖苷与葡糖蓝精蛋白的比例增加。 一般方法包括制备水提取物,使含水提取物与吸附剂接触,除去吸附剂以获得含有硫代葡萄糖苷的提取物,干燥含有硫代葡萄糖苷的提取物以获得含有硫代葡萄糖苷的干燥提取物,将至少一部分 干燥的含有硫代葡萄糖苷的提取物与溶剂形成含有硫代葡萄糖苷的悬浮液,澄清含有硫代葡萄糖苷的悬浮液,使含有硫代葡萄糖苷的悬浮液与催化剂接触,并引入氢气足以获得富含化学保护剂前体的提取物。 可以进一步处理富含化学保护剂前体的提取物,以形成富含化学保护剂前体的分离物,或加工用于各种应用,包括掺入各种食品和药物中。