Multipotent prenatal stem cells
    3.
    发明授权

    公开(公告)号:US09700585B2

    公开(公告)日:2017-07-11

    申请号:US14038274

    申请日:2013-09-26

    摘要: The present invention relates to the isolation, propagation and use of prenatal stem cells. The cells are CD105 negative. In certain embodiments the cells are also SSEA-4 positive or negative, and c-kit negative. The cells may be isolated from a prenatal sample, for instance third trimester amniotic fluid or placental membrane. The cells may be combined with a biologically compatible solution or a biologically compatible matrix and utilized to treat a human subject. The invention also contemplated enriched populations of prenatal stem cells. The enriched cell population may be propagated in the appropriate culture medium and the resulting progeny cells utilized therapeutic applications.

    Osteoconductive implants and methods of using same
    4.
    发明授权
    Osteoconductive implants and methods of using same 有权
    骨诱导性植入物及其使用方法

    公开(公告)号:US09539104B2

    公开(公告)日:2017-01-10

    申请号:US13750212

    申请日:2013-01-25

    摘要: Implants for promoting bone growth and methods of using same, the implants including a perforated placental membrane sheet wrapped around an osteoconductive material composed of bone chips, bone granules, bone powders or combinations thereof, the osteoconductive material being configured for providing a scaffold upon which bone growth can occur. The placental membrane sheet acts to maintain the osteoconductive material in a cohesive, organized configuration within a site of a patient where bone growth is to be induced. The perforations in the placental membrane sheet create passageways in the exterior of the implant through which the osteoconductive material can communicate with adjacent bone surfaces which are to be fused.

    摘要翻译: 用于促进骨生长的植入物及其使用方法,所述植入物包括围绕由骨碎片,骨颗粒,骨粉或其组合组成的骨传导材料缠绕的穿孔胎盘膜片,所述骨传导材料被配置用于提供骨架 可能会发生增长。 胎盘膜片用于将骨传导性材料保持在患有骨生长诱导的患者的位置内的内聚性,有组织的构型。 胎盘膜片中的穿孔在植入物的外部形成通道,骨传导材料可以通过该通道与待融合的相邻骨表面连通。

    Sacroiliac Joint Stabilization Method
    6.
    发明申请
    Sacroiliac Joint Stabilization Method 有权
    骶髂关节稳定方法

    公开(公告)号:US20140277165A1

    公开(公告)日:2014-09-18

    申请号:US13826564

    申请日:2013-03-14

    IPC分类号: A61B17/70

    摘要: A method for treating back pain by stabilizing the sacroiliac joint. The method includes fusing a sacrum bone to an ilium bone or otherwise mechanically immobilizing the sacroiliac joint by inserting at least two implants into voids formed within or between the articular surfaces of each sacroiliac joint of a patient without substantially distracting the joint. The voids are arranged within each joint at either a converging orientation or a diverging orientation. A kit containing the implants and tools required to insert the implants into the joint are also described.

    摘要翻译: 通过稳定骶髂关节来治疗腰痛的方法。 该方法包括将骶骨融合到髂骨或通过将至少两个植入物插入到形成在患者的每个骶髂关节的关节表面之内或之间的空隙中而不会使关节基本上分散的情况下将骶骨骨融合或以其他方式机械固定骶髂关节。 空隙以收敛方向或发散方向布置在每个接头内。 还描述了包含将植入物插入关节所需的植入物和工具的试剂盒。

    Expandable Placental Membrane and Methods of Making and Storing Same
    8.
    发明申请
    Expandable Placental Membrane and Methods of Making and Storing Same 审中-公开
    可膨胀胎盘膜及其制备和储存方法

    公开(公告)号:US20130084314A1

    公开(公告)日:2013-04-04

    申请号:US13647525

    申请日:2012-10-09

    IPC分类号: A61K35/50 C12N5/071 A61K9/00

    摘要: A placental membrane including a plurality of slits for increasing the membrane's capacity to expand. The slits are provided through the membrane and provided in sufficient numbers across the surfaces of the membrane to produce a mesh-like pattern in the membrane. The mesh-like pattern enables the placental membrane to be stretched and therefore increased in length and width. For ease of handling and storage, the expandable placental membrane is removably adhered to a backing, rolled into a cylinder and placed within a capped vial containing a solution of amniotic fluid cells for improving the effectiveness of the membrane.

    摘要翻译: 一种胎盘膜,包括多个狭缝,用于增加膜的扩张能力。 狭缝通过膜提供并且以足够数量提供在膜的表面上以在膜中产生网状图案。 网状图案能够使胎盘膜被拉伸,因此长度和宽度增加。 为了易于处理和储存,可扩张胎盘膜可移除地粘附到背衬上,卷成圆筒并放置在含有羊水细胞溶液的封盖小瓶中,以改善膜的有效性。

    Facet buttress implant and method of using same

    公开(公告)号:US10702313B1

    公开(公告)日:2020-07-07

    申请号:US15701423

    申请日:2017-09-11

    发明人: Kenneth L. Horton

    摘要: A surgical implant for preventing withdrawal of a bone dowel graft from a facet joint, the apparatus including a plate having a posterior face and an anterior face, a passageway extending to and between the posterior face and the anterior face, an opening through the posterior face that is configured for detachably coupling to an inserter and one or more anti-migration projections extending outwardly from the anterior face. In use, the plate is placed over a bone dowel seated in a facet joint and coupled to the superior process and the inferior process by inserting a screw through the passageway into the inferior process.