公开(公告)号：US06692762B2

公开(公告)日：2004-02-17

申请号：US09500475

申请日：2000-02-09

申请人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

发明人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

IPC分类号： A61K906

CPC分类号： C12P7/6427 ,  A23D9/00 ,  A23L33/115 ,  C12P7/6436 ,  C12P7/6472 ,  C12P7/6481 ,  C12P7/649 ,  Y02E50/13 ,  Y10S426/807

摘要： Compositions comprising glycerides containing conjugated linoleic acid moieties. These glycerides are prepared by an enzymatic conversion process which is selective to provide specific isomers, advantageously the cis9, trans11 and trans10, cis12 linoleic acid isomers or vice versa. The compositions may be blended with complementary fats and may be used in foods, food supplements and pharmaceutical compositions.

摘要翻译： 包含含有共轭亚油酸部分的甘油酯的组合物。 这些甘油酯通过酶转化方法制备，其可选择性地提供特异性异构体，有利地是顺式9，反式11和反式10，顺式12亚油酸异构体，反之亦然。 组合物可以与互补脂肪混合并且可以用于食品，食品添加剂和药物组合物中。

公开(公告)号：US06184009B2

公开(公告)日：2001-02-06

申请号：US09068154

申请日：1998-09-30

申请人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

发明人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

IPC分类号： C12P764

CPC分类号： C12P7/6427 ,  A23D9/00 ,  A23L33/115 ,  C12P7/6436 ,  C12P7/6472 ,  C12P7/6481 ,  C12P7/649 ,  Y02E50/13 ,  Y10S426/807

摘要： A process for preparing a material B comprising geometrical isomers L1 and L2 of conjugated linoleic acid moieties in a specific weight ratio of XB wherein a material A selected from free fatty acids, mono-, di- or tri-glycerides, phospholipids, alkyl esters or wax-esters containing at least 5 weight % of L1 and L2 are subjected to enzymatic conversion using an enzyme that can discriminate between L1 and L2 so that the original weight ratio of L1 to L2 of XA in the starting material is increased to XB where XB is equal to or greater than 1.1 XA. Advantageously, the isomers L1 and L2 are cis9, trans11 and trans10, cis12 linoleic acid or vice versa. The enzyme is advantageously a lipase obtained from Geotrichum candidum or Candida rugosa or a phospholipase. The starting material A may be, for example, a fish oil or vegetable oil. The resulting products may be blended with a complementary fat and may be used as foods or food supplements or in pharmaceutical compositions.

摘要翻译： 一种制备材料B的方法，其包含XB的特定重量比的共轭亚油酸部分的几何异构体L1和L2，其中选自游离脂肪酸，单 - ，二 - 或三 - 甘油酯，磷脂，烷基酯或 含有至少5重量％的L1和L2的蜡酯使用可以区分L1和L2的酶进行酶转化，使得起始原料中XA的初始重量比L1至L2增加到XB，其中XB 等于或大于1.1 XA。 有利地，异构体L1和L2是顺式9，反式11和反式10，顺式12亚油酸或反之亦然。 所述酶有利地是从地高赤霉素或假丝酵母或磷脂酶获得的脂肪酶。 原料A可以是例如鱼油或植物油。 所得产品可与互补脂肪混合，并可用作食品或食品添加剂或药物组合物。

公开(公告)号：US06534663B1

公开(公告)日：2003-03-18

申请号：US09713009

申请日：2000-11-16

申请人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

发明人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

IPC分类号： C07C5700

CPC分类号： C12P7/6427 ,  A23D9/00 ,  A23L33/115 ,  C12P7/6436 ,  C12P7/6472 ,  C12P7/6481 ,  C12P7/649 ,  Y02E50/13 ,  Y10S426/807

摘要： Organic materials, comprising a mixture of at least two products (I) and (II), both containing isomers of conjugated long chain polyunsaturated fatty acid moieties L1 and L2 can be obtained by subjecting an organic material, selected from free fatty acids, mono-, di- or tri-glycerides, phospholipids, alkyl esters or wax-esters containing at least 5 weight % of these conjugated polyunsaturated fatty acids, to an enzymatic conversion using an enzyme that can discriminate between L1 and L2, so that the original weight ratio of L1/L2=XA in the starting material is increased to XB wherein XB≧than 1.1 XA.

摘要翻译： 包含至少两种含有共轭长链多不饱和脂肪酸部分L1和L2的异构体的产物（I）和（II）的混合物的有机材料可以通过使选自游离脂肪酸，单 - ，含有至少5重量％的这些共轭多不饱和脂肪酸的二 - 或三 - 甘油酯，磷脂，烷基酯或蜡 - 酯，使用可以区分L1和L2的酶进行酶转化，使得原始重量比 的起始原料中的L1 / L2 = XA增加到XB，其中XB> = 1.1XA。

公开(公告)号：US06534110B1

公开(公告)日：2003-03-18

申请号：US10180503

申请日：2002-06-27

申请人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

发明人： Frederick William Cain ,  Stephen Raymond Moore ,  Gerald Patrick McNeill ,  Olga Cornelia Zwemmer

IPC分类号： A23D700

CPC分类号： C12P7/6427 ,  A23D9/00 ,  A23L33/115 ,  C12P7/6436 ,  C12P7/6472 ,  C12P7/6481 ,  C12P7/649 ,  Y02E50/13 ,  Y10S426/807

摘要： Organic materials, comprising a mixture of at least two products (I) and (II), both containing isomers of conjugated long chain polyunsaturated fatty acids moieties (L1) and (L2) can be obtained by subjecting an organic material, selected from free fatty acids, mono-, di- or triglycerides, phospholipids, alkylesters or wax-esters, containing at least 5 wt. % of these conjugated polyunsaturated fatty acids, to an enzymic conversion (acidolysis, alcoholysis, esterification, hydrolysis) using an enzyme that can be discriminated between (L1) and (L2), so that original ratio L1/L2=XA in starting material is increased to XB, wherein XB≧1.1 XA.

摘要翻译： 包含至少两种含有共轭长链多不饱和脂肪酸部分（L1）和（L2）的异构体的产物（I）和（II）的混合物的有机材料可以通过使有机材料选自游离脂肪 酸，单酸，二或甘油三酸酯，磷脂，烷基酯或蜡 - 酯，含有至少5wt。 ％的这些共轭多不饱和脂肪酸，使用可以在（L1）和（L2）之间区分的酶进行酶转化（酸解，醇解，酯化，水解），使原料的原始比率L1 / L2 = XA为 增加到XB，其中XB> = 1.1XA。

公开(公告)号：US06277430B1

公开(公告)日：2001-08-21

申请号：US09403546

申请日：2000-01-27

申请人： Frederick William Cain ,  Anne Hailes ,  Leo Frans Vermaas ,  Olga Cornelia Zwemmer

发明人： Frederick William Cain ,  Anne Hailes ,  Leo Frans Vermaas ,  Olga Cornelia Zwemmer

IPC分类号： A23D9007

CPC分类号： A23D7/0056 ,  A23D7/0053 ,  A23D7/015 ,  B01F17/0092

摘要： Novel fat-continous emulsion, containing a blend with emulsifying properties is obtained by the blending of: 0-90% of a partial glyceride (=A); 0-80% of a phospholipid (=B); 0.01-99.98% of a long chain alcohol having >20 C-atoms in the alcohol chain, while the amount of (A)+(B)≧0.02% and incorporating this blend in a fat-continuous emulsion.

摘要翻译： 通过以下方式获得含有乳化性能的共混物的新型脂肪连续乳液：0-90％的偏甘油酯（= A）; 0-80％的磷脂（= B）; 0.01-99.98％的醇链中具有> 20个C原子的长链醇，而（A）+（B）> = 0.02％的量，并将该共混物掺入脂肪连续乳液中。