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1.发明授权Sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans for treating diseases caused by the influenza virus 有权用于治疗由流感病毒引起的疾病的硫酸阿拉伯半乳聚糖，阿维拉半乳糖醛酸和硫酸化杂多糖公开(公告)号：US09011939B2
公开(公告)日：2015-04-21
申请号：US13977780
申请日：2012-01-03
申请人： Bruno Lina , Olivier Ferraris , Ho Hong Hai Vo , François-Loïc Cosset , Judit Szecsi , Alain Heyraud , Hugues Lortat-Jacob , Julia Bartoli , Rabia Sadir , Thierry Livache , Benoît Darblade , Stéphane Havet , Silvère Bonnet
发明人： Bruno Lina , Olivier Ferraris , Ho Hong Hai Vo , François-Loïc Cosset , Judit Szecsi , Alain Heyraud , Hugues Lortat-Jacob , Julia Bartoli , Rabia Sadir , Thierry Livache , Benoît Darblade , Stéphane Havet , Silvère Bonnet
IPC分类号： A01N65/00 , A61K31/737 , A61K31/715 , A61K36/05 , A61K36/888
CPC分类号： A61K31/737 , A61K31/715 , A61K36/05 , A61K36/888
摘要： The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.
摘要翻译： 本发明涉及旨在用作预防或治疗性流感病毒的药物的硫酸化阿拉伯半乳聚糖，阿片半乳糖聚糖和硫酸化异糖聚糖的多糖，以及该药物组合物，特别是与至少一种 药学上可接受的载体：脆弱的Codium的提取物，包括硫酸化的阿拉伯半乳聚糖，或Zostera marina或Lemna minor的提取物，包括半乳糖醛酸聚糖或包括硫酸化杂聚糖的Caulerpa racemosa的提取物。
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2.发明授权Modified viral strains and method for improving the production of vaccine seeds of influenza virus 有权改良病毒株及改良流感病毒疫苗种子生产的方法公开(公告)号：US08956626B2
公开(公告)日：2015-02-17
申请号：US13809629
申请日：2011-07-08
IPC分类号： A61K39/145 , C07K14/005 , C12N7/00 , C12N7/04
CPC分类号： A61K39/145 , C07K14/005 , C12N7/00 , C12N2760/16121 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151
摘要： Modified influenza A/PR/8/34 virus and reassortant influenza A/PR/8/34 virus including a modified PB1 gene and methods for improving the production of HA (hemagglutinin) and NA (neuraminidase) vaccine glycoproteins.
摘要翻译： 包括修饰的PB1基因的改良的流感A / PR / 8/34病毒和重配流感A / PR / 8/34病毒和改善HA（血凝素）和NA（神经氨酸酶）疫苗糖蛋白的产生的方法。
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3.发明申请公开(公告)号：US20130115242A1
公开(公告)日：2013-05-09
申请号：US13809629
申请日：2011-07-08
IPC分类号： A61K39/145 , C12N7/00
CPC分类号： A61K39/145 , C07K14/005 , C12N7/00 , C12N2760/16121 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151
摘要： Modified influenza A/PR/8/34 virus and reassortant influenza A/PR/8/34 virus including a modified PB1 gene and methods for improving the production of HA (hemagglutinin) and NA (neuraminidase) vaccine glycoproteins.
摘要翻译： 包括修饰的PB1基因的改良的流感A / PR / 8/34病毒和重配流感A / PR / 8/34病毒以及用于改善HA（血凝素）和NA（神经氨酸酶）疫苗糖蛋白的产生的方法。
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4.发明申请SULPHATED ARABINOGALACTANS, APIOGALACTURONANS AND SULPHATED HETEROGLYCANS FOR TREATING DISEASES CAUSED BY THE INFLUENZA VIRUS 有权用于治疗由流感病毒引起的疾病的硫酸化阿拉伯胶原蛋白，APIOGALACTURONANS和硫化异黄酮公开(公告)号：US20140023675A1
公开(公告)日：2014-01-23
申请号：US13977780
申请日：2012-01-03
申请人： Bruno Lina , Olivier Ferraris , Ho Hong Hai Vo , Francois-Loic Cosset , Judit Szecsi , Alain Heyraud , Hugues Lortat-Jacob , Julia Bartoli , Rabia Sadir , Thierry Livache , Benoit Darblade , Stephane Havet , Silvére Bonnet
发明人： Bruno Lina , Olivier Ferraris , Ho Hong Hai Vo , Francois-Loic Cosset , Judit Szecsi , Alain Heyraud , Hugues Lortat-Jacob , Julia Bartoli , Rabia Sadir , Thierry Livache , Benoit Darblade , Stephane Havet , Silvére Bonnet
IPC分类号： A61K31/737
CPC分类号： A61K31/737 , A61K31/715 , A61K36/05 , A61K36/888
摘要： The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.
摘要翻译： 本发明涉及旨在用作预防或治疗性流感病毒的药物的硫酸化阿拉伯半乳聚糖，阿片半乳糖聚糖和硫酸化异糖聚糖的多糖，以及该药物组合物，特别是与至少一种 药学上可接受的载体：脆弱的Codium的提取物，包括硫酸化的阿拉伯半乳聚糖，或Zostera marina或Lemna minor的提取物，包括半乳糖醛酸聚糖或包括硫酸化杂聚糖的Caulerpa racemosa的提取物。
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