公开(公告)号：US07015048B2

公开(公告)日：2006-03-21

申请号：US10038192

申请日：2002-01-02

Applicant: Pierre Delmas ,  Patrick Garnero ,  Evelyne Gineyts

Inventor： Pierre Delmas ,  Patrick Garnero ,  Evelyne Gineyts

IPC: G01N33/53

CPC classification number: G01N33/6887 ,  G01N33/5308 ,  G01N33/564 ,  G01N2333/78 ,  G01N2800/52 ,  Y10S436/811

Abstract: Disclosed are specific markers for synovial tissue degradation and methods of using the markers in diagnosing, monitoring or determining a prognosis of synovial disease.

Abstract translation: 公开了用于滑膜组织降解的特异性标记物和在诊断，监测或确定滑膜疾病预后中使用标记物的方法。

公开(公告)号：US1863688A

公开(公告)日：1932-06-21

申请号：US51638731

申请日：1931-02-17

Applicant: PIERRE DELMAS

Inventor： PIERRE DELMAS

IPC: B60Q1/44

CPC classification number: B60Q1/447

公开(公告)号：US3695764A

公开(公告)日：1972-10-03

申请号：US3695764D

申请日：1970-12-01

Applicant: PIERRE DELMAS ,  PIERRE IMBERT

Inventor： DELMAS PIERRE ,  IMBERT PIERRE

IPC: G01J3/06 ,  G01N21/31 ,  G01J3/42 ,  G01J3/12 ,  G01N21/04

CPC classification number: G01J3/06 ,  G01N21/314

Abstract: An automatic spectrophotometric absorption analyzer for continuous determination of a plurality of components of a fluid sample, comprising a monochromator with a diffraction grating receiving the light transmitted by a vessel with transparent faces which contains said sample, a photoelectric converter so arranged that the light beam emerging from the monochromator falls on its sensitive element, a unit for determining cyclically a plurality of stop positions of said diffraction grating which define wavelengths corresponding to the absorption lines of components of said sample, and means for automatic computation of the concentration of said components from the signal which is delivered by the converter.

Abstract translation: 一种用于连续测定流体样品的多个组分的自动分光光度吸收分析仪，包括具有衍射光栅的单色仪，所述衍射光栅接收由容器透射的光，所述透明面包含所述样品;光电转换器，其布置成使得所述光束出现 单色器落在其敏感元件上，用于周期性地确定所述衍射光栅的多个停止位置的单元，其限定与所述样品的组分的吸收线对应的波长，以及用于自动计算所述组分的浓度的装置， 由转换器传送的信号。

公开(公告)号：US6004765A

公开(公告)日：1999-12-21

申请号：US442138

申请日：1995-05-16

Applicant: Pierre Delmas

Inventor： Pierre Delmas

IPC: C07K16/44 ,  G01N33/68 ,  C07K16/00 ,  G01N33/53 ,  G01N33/543

CPC classification number: C07K16/44 ,  G01N33/68 ,  G01N33/6893 ,  Y10S435/81 ,  Y10S435/975 ,  Y10S436/808 ,  Y10S436/811

Abstract: A method for the assessment of bone fragility and osteoporosis fracture risk characterized by:measuring in vitro the concentration of under-carboxylated osteocalcin in a biological fluid sample such as serum, plasma or urine;comparing the concentration of under-carboxylated osteocalcin in the test sample with the concentration in a control sample containing levels of under-carboxylated osteocalcin representative of the upper limit of the normal range, concentrations above this upper limit being indicative of increased risk of bone fracture.

Abstract translation: 一种评估骨骼脆性和骨质疏松症骨折风险的方法，其特征在于：在体外测量生物流体样品如血清，血浆或尿液中未羧化的骨钙素的浓度; 将测试样品中未羧化的骨钙素的浓度与含有代表正常范围上限的低羧基化骨钙素含量的对照样品中的浓度进行比较，高于该上限的浓度表示骨折的风险增加。