-
公开(公告)号：US20200016051A1
公开(公告)日：2020-01-16
申请号：US16577416
申请日：2019-09-20
IPC分类号： A61K8/11 , A61K6/00 , A61K8/87 , A61Q19/00 , A61Q5/12 , A61K8/64 , A61Q5/06 , A61Q5/02 , A61Q3/02 , A61K8/19 , A61K8/21 , A61K8/24 , A61K9/00 , A61K9/50 , A61Q11/00 , A61K47/02 , A61K33/44 , A61K33/16 , A61K33/06 , A61Q13/00 , A61Q17/00 , A61Q17/02
摘要： A microcapsule composition comprising at least one polymer substantially disposed as a semipermeable shell around an aqueous buffered solution and at least one agent, wherein the agent permeates the shell, and wherein the composition is suitable for delivery to a mammal.
-
公开(公告)号：US10434047B2
公开(公告)日：2019-10-08
申请号：US16207545
申请日：2018-12-03
IPC分类号： A61K8/11 , A61K6/00 , A61Q13/00 , A61K33/44 , A61K33/16 , A61Q11/00 , A61K9/50 , A61K8/87 , A61Q19/00 , A61Q5/12 , A61K8/64 , A61Q5/06 , A61Q5/02 , A61Q3/02 , A61K8/19 , A61K8/21 , A61K8/24 , A61K9/00 , A61K47/02 , A61K33/06 , A61Q17/00 , A61Q17/02
摘要： A microcapsule composition comprising at least one polymer substantially disposed as a semi-permeable shell around an aqueous buffered solution and at least one agent, wherein the agent permeates the shell, and wherein the composition is suitable for delivery to a mammal.
-
公开(公告)号：US09585818B2
公开(公告)日：2017-03-07
申请号：US14251284
申请日：2014-04-11
发明人： William A. Mchale , Dale G. Brown
CPC分类号： A61Q11/00 , A61K8/062 , A61K8/21 , A61K8/23 , A61K8/362 , A61K8/365 , A61K8/891 , A61K8/90 , A61K9/006 , A61K9/0063 , A61K9/107 , A61K2800/31
摘要： Substantially aqueous-free, enamel protectant and enamel repair toothpaste treatments containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpaste treatments indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.
摘要翻译： 基本无水的搪瓷保护剂和牙釉质修复牙膏处理，其包含：氟化亚锡，钙和直接剂，其包含：非离子表面活性剂中聚二甲基硅氧烷的乳液，其中：（a）所述氟化亚锡和钙的直接性存在于釉质上的生物膜 通过在氟化亚锡存在下从双齿到单齿的钙结合而增强; 和（b）与具有相当或更高氟化物水平的氟化物刷洗治疗相比，所述牙膏处理表明显着改善，釉质保护因子（EPF）和釉质修复因子（ERF）值。
-
公开(公告)号：US20140301956A1
公开(公告)日：2014-10-09
申请号：US14251104
申请日：2014-04-11
发明人： William A. MCHALE , Dale G. BROWN
CPC分类号： A61Q11/00 , A61K8/062 , A61K8/21 , A61K8/23 , A61K8/362 , A61K8/365 , A61K8/891 , A61K8/90 , A61K9/006 , A61K9/0063 , A61K9/107 , A61K2800/31
摘要： A method of treatment for enamel with substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.
摘要翻译： 一种治疗具有基本上无水的釉质保护剂和修复刷牙凝胶的搪瓷的方法，所述釉质含有：氟化亚锡，钙和直接剂，其包含：非离子表面活性剂中的聚二甲基硅氧烷的乳液，其中所述氟化亚锡和钙的直接存在于生物膜中 在氟化亚锡的存在下，通过钙结合从二齿转变为单齿来增强釉质; 并且与具有相当或更高氟化物水平的氟化物刷洗治疗相比，所述刷牙具有显着改善的釉质保护因子（EPF）和釉质修复因子（ERF）值。
-
公开(公告)号：US20220079849A1
公开(公告)日：2022-03-17
申请号：US17456271
申请日：2021-11-23
IPC分类号： A61K8/11 , A61K8/87 , A61Q19/00 , A61Q5/12 , A61K8/64 , A61Q5/06 , A61Q5/02 , A61Q3/02 , A61K8/19 , A61K8/21 , A61K8/24 , A61K9/00 , A61K9/50 , A61Q11/00 , A61K47/02 , A61K33/44 , A61K33/16 , A61K33/06 , A61Q13/00 , A61Q17/00 , A61Q17/02 , A61K6/20 , A61K6/69 , A61K6/71
摘要： A microcapsule composition comprising at least one polymer substantially disposed as a semipermeable shell around an aqueous buffered solution and at least one agent, wherein the agent permeates the shell, and wherein the composition is suitable for delivery to a mammal.
-
公开(公告)号：US11185480B2
公开(公告)日：2021-11-30
申请号：US16577416
申请日：2019-09-20
IPC分类号： A61K8/11 , A61K6/20 , A61K8/19 , A61K8/21 , A61Q13/00 , A61Q17/00 , A61Q17/02 , A61K8/87 , A61Q19/00 , A61Q5/12 , A61K8/64 , A61Q5/06 , A61Q5/02 , A61Q3/02 , A61K8/24 , A61K9/00 , A61K9/50 , A61Q11/00 , A61K47/02 , A61K33/44 , A61K33/16 , A61K33/06 , A61K6/69 , A61K6/71
摘要： A microcapsule composition comprising at least one polymer substantially disposed as a semipermeable shell around an aqueous buffered solution and at least one agent, wherein the agent permeates the shell, and wherein the composition is suitable for delivery to a mammal.
-
公开(公告)号：US20200009028A1
公开(公告)日：2020-01-09
申请号：US16577212
申请日：2019-09-20
IPC分类号： A61K8/11 , A61K8/19 , A61K8/21 , A61K8/24 , A61K9/00 , A61K9/50 , A61K33/06 , A61K33/16 , A61K33/44 , A61K47/02 , A61Q11/00 , A61Q3/02 , A61Q5/02 , A61Q5/06 , A61K8/64 , A61Q5/12 , A61Q19/00 , A61K8/87 , A61K6/00
摘要： A microcapsule composition comprising at least one polymer substantially disposed as a semipermeable shell around a buffered solution and at least one therapeutic agent, wherein the therapeutic agent permeates the shell, and wherein the composition is suitable for delivery to a mammal. This invention also provides related compositions, products and methods.
-
公开(公告)号：US20170296440A1
公开(公告)日：2017-10-19
申请号：US15513526
申请日：2015-09-24
摘要： A composition comprising microcapsules functionalized with polymerizable functional groups on the surface of said microcapsules wherein the functional groups form covalent bonds with monomers in the continuous phase to enhance the mechanical properties of the composition.
-
公开(公告)号：US09586064B2
公开(公告)日：2017-03-07
申请号：US14251149
申请日：2014-04-11
发明人： William A. McHale , Dale G. Brown
CPC分类号： A61Q11/00 , A61K8/062 , A61K8/21 , A61K8/23 , A61K8/362 , A61K8/365 , A61K8/891 , A61K8/90 , A61K9/006 , A61K9/0063 , A61K9/107 , A61K2800/31
摘要： Substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.
摘要翻译： 基本无水的搪瓷保护剂和修复刷牙凝胶，其含有：氟化亚锡，钙和直接剂，其包含：非离子表面活性剂中的聚二甲基硅氧烷的乳液，其中通过钙结合增强所述氟化亚锡和钙在生物膜中的直接性 在氟化亚锡的存在下，从二齿变为单齿; 并且与具有相当或更高氟化物水平的氟化物刷洗治疗相比，所述刷牙具有显着改善的釉质保护因子（EPF）和釉质修复因子（ERF）值。
-
公开(公告)号：US20140294741A1
公开(公告)日：2014-10-02
申请号：US14251284
申请日：2014-04-11
发明人： William A. MCHALE , Dale G. BROWN
CPC分类号： A61Q11/00 , A61K8/062 , A61K8/21 , A61K8/23 , A61K8/362 , A61K8/365 , A61K8/891 , A61K8/90 , A61K9/006 , A61K9/0063 , A61K9/107 , A61K2800/31
摘要： Substantially aqueous-free, enamel protectant and enamel repair toothpaste treatments containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpaste treatments indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.
摘要翻译： 基本无水的搪瓷保护剂和牙釉质修复牙膏处理，其包含：氟化亚锡，钙和直接剂，其包含：非离子表面活性剂中聚二甲基硅氧烷的乳液，其中：（a）所述氟化亚锡和钙的直接性存在于釉质上的生物膜 通过在氟化亚锡存在下从双齿到单齿的钙结合而增强; 和（b）与具有相当或更高氟化物水平的氟化物刷洗治疗相比，所述牙膏处理表明显着改善，釉质保护因子（EPF）和釉质修复因子（ERF）值。
-
-
-
-
-
-
-
-
-
搜索结果
32 条记录 (耗时 0.025 秒)
