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公开(公告)号:US20120238751A1
公开(公告)日:2012-09-20
申请号:US13496188
申请日:2012-03-14
申请人: Daniel Bensen , Zhiyong Chen , John Finn , Thanh To Lam , Suk Joong Lee , Xiaoming Li , Douglas W. Phillipson , Leslie William Tari , Michael Trzoss , Junhu Zhang , Felice C. Lightstone , Toan B. Nguyen , Sergio E. Wong , Paul Aristoff , Michael Jung
发明人: Daniel Bensen , Zhiyong Chen , John Finn , Thanh To Lam , Suk Joong Lee , Xiaoming Li , Douglas W. Phillipson , Leslie William Tari , Michael Trzoss , Junhu Zhang , Felice C. Lightstone , Toan B. Nguyen , Sergio E. Wong , Paul Aristoff , Michael Jung
IPC分类号: C07D487/04 , C07D471/10 , C07D487/08 , C07D471/08 , C07D487/10 , C07D491/048 , C07D491/056 , C07D487/14 , C07D471/14 , C07D471/04 , C07D498/04
CPC分类号: C07D487/04 , C07D487/14
摘要: Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
摘要翻译: 本文公开了具有式I结构的化合物及其药学上合适的盐,酯和前药,其可用作抗菌三环类回旋酶抑制剂。 还考虑了相关的药物组合物,用途和制备化合物的方法。
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公开(公告)号:US09732083B2
公开(公告)日:2017-08-15
申请号:US13496188
申请日:2012-03-14
申请人: Daniel Bensen , Zhiyong Chen , John Finn , Thanh To Lam , Suk Joong Lee , Xiaoming Li , Douglas W. Phillipson , Leslie William Tari , Michael Trzoss , Junhu Zhang , Felice C. Lightstone , Toan B. Nguyen , Sergio E. Wong , Paul Aristoff , Michael Jung
发明人: Daniel Bensen , Zhiyong Chen , John Finn , Thanh To Lam , Suk Joong Lee , Xiaoming Li , Douglas W. Phillipson , Leslie William Tari , Michael Trzoss , Junhu Zhang , Felice C. Lightstone , Toan B. Nguyen , Sergio E. Wong , Paul Aristoff , Michael Jung
IPC分类号: C07D487/04 , C07D487/14
CPC分类号: C07D487/04 , C07D487/14
摘要: Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
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