PHOTOTHERMAL SUBSTRATES FOR SELECTIVE TRANSFECTION OF CELLS
    2.
    发明申请
    PHOTOTHERMAL SUBSTRATES FOR SELECTIVE TRANSFECTION OF CELLS 审中-公开
    用于选择性转染细胞的光热底物

    公开(公告)号:US20150044751A1

    公开(公告)日:2015-02-12

    申请号:US14117543

    申请日:2012-05-14

    IPC分类号: C12M1/42 C12N13/00

    摘要: This invention provides novel tools for surgery on single cells and substrates/devices for delivery of reagents to selected cells. In certain embodiments the substrates comprise a surface comprising one or more orifices, where nanoparticles and/or a thin film is deposited on a surface of said orifice or near said orifice, where the nanoparticles and/or a thin film are formed of materials that heat up when contacted with electromagnetic radiation. In certain embodiments the pores are in fluid communication with microchannels containing one or more reagents to be delivered into the cells.

    摘要翻译: 本发明提供用于在单细胞和底物/装置上手术的新型工具,用于将试剂递送至所选择的细胞。 在某些实施方案中,基底包括包含一个或多个孔的表面,其中纳米颗粒和/或薄膜沉积在所述孔的表面上或所述孔附近,其中纳米颗粒和/或薄膜由热的材料形成 当与电磁辐射接触时。 在某些实施方案中,孔与含有待递送至细胞中的一种或多种试剂的微通道流体连通。