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    Microdosing apparatus and method for dosed dispensing of liquids
    3.
    发明申请
    Microdosing apparatus and method for dosed dispensing of liquids 有权
    用于液体配药的微量滴定装置和方法

    公开(公告)号：US20060147313A1

    公开(公告)日：2006-07-06

    申请号：US11353681

    申请日：2006-02-14

    申请人： Roland Zengerle ,  Peter Koltay ,  Wolfgang Streule ,  Gerhard Birkle

    发明人： Roland Zengerle ,  Peter Koltay ,  Wolfgang Streule ,  Gerhard Birkle

    IPC分类号： F04B49/06 ,  F04B17/00 ,  F04B43/12

    CPC分类号： B01L3/0268 ,  B01L2300/0838 ,  B01L2300/123 ,  B01L2400/0481 ,  Y10S239/12

    摘要： A microdosing apparatus comprises a fluid conduit having a flexible tube with a first end for connecting to a fluid reservoir and a second end where an outlet opening is located. An actuating device with a displacer with adjustable hub is provided, by which the volume of a portion of the flexible hub can be changed to thereby dispense liquid as free flying droplets or as free flying jet at the outlet opening by moving the displacer between a first end position and a second end position, whereby the tube is partly compressed in the first or the second end position. In other words, a microdosing apparatus comprises fluid conduit having a portion along which a cross section of the fluid conduit is variable by an actuating device to effect a change of the volume of the fluid conduit. A ratio of a fluidic impedance between the position of the actuating device and the outlet opening to a fluidic impedance between a first end of the fluid conduit and the position of the actuating device is variable by changing the position of the actuating device, so that a dosing volume dispensed at the outlet opening is variable thereby by at least 10%.

    摘要翻译： 微量给药装置包括具有柔性管的流体导管，其具有用于连接到流体储存器的第一端和位于出口开口的第二端。 提供具有可调节轮毂的置换器的致动装置，通过该致动装置可以改变柔性轮毂的一部分的体积，从而以自由飞行液滴的方式分配液体，或者在出口处通过移动置换器在第一 末端位置和第二端部位置，由此管部分地在第一或第二端部位置被压缩。 换句话说，微量滴定装置包括流体导管，其具有一部分，流体导管的横截面沿着该部分可由致动装置变化，以实现流体导管体积的变化。 驱动装置的位置与出口之间的流体阻抗与流体导管的第一端与致动装置的位置之间的流体阻抗的比值可通过改变致动装置的位置而变化，从而使 在出口处分配的给药量可变至少10％。

    Device and method for generating a drop of a liquid
    4.
    发明授权
    Device and method for generating a drop of a liquid 有权
    用于产生液滴的装置和方法

    公开(公告)号：US08877145B2

    公开(公告)日：2014-11-04

    申请号：US13106206

    申请日：2011-05-12

    申请人： Tobias Metz ,  Peter Koltay

    发明人： Tobias Metz ,  Peter Koltay

    IPC分类号： B01L3/02 ,  B22D41/005 ,  B41J2/21

    CPC分类号： B41J2/211

    摘要： A device for generating a drop of a primary liquid is described, including: a reservoir fillable with the primary liquid, a pressure generation device for generating a hydraulic pressure on the primary liquid, at least one inlet channel for introducing a secondary fluid, and a channel having a flow cross-section transverse to a main flow direction, wherein the flow cross-section includes a main region and at least one sub-region extending from the main region, designed such that the primary liquid can be held in the main region by capillary forces, and the secondary fluid can be held in the sub-region by capillary forces, wherein the reservoir is fluidically connected to a first end of the channel via an output opening, and the at least one inlet channel is also fluidically connected to the channel, and wherein the pressure generation device is implemented to apply a hydraulic pressure to the primary liquid, whereby the same is moved along the channel and output at a second end of the channel as free-flying drop.

    摘要翻译： 描述了用于产生一次液体的液滴的装置，包括：可用主液体填充的储存器，用于在主液体上产生液压的压力产生装置，用于引入次流体的至少一个入口通道和 所述流路截面包括主区域和从所述主区域延伸的至少一个子区域，其被设计成使得所述主液体能够保持在所述主区域中 通过毛细管力，并且次级流体可以通过毛细管力保持在子区域中，其中储存器经由输出开口流体连接到通道的第一端，并且至少一个入口通道也流体连接到 所述通道，并且其中所述压力发生装置被实施为向所述主要液体施加液压，由此所述压力产生装置沿着所述通道移动并在所述第二端部输出 频道作为自由飞行的下降。

    DEVICE AND METHOD FOR GENERATING A DROP OF A LIQUID
    6.
    发明申请
    DEVICE AND METHOD FOR GENERATING A DROP OF A LIQUID 有权
    用于产生液体液体的装置和方法

    公开(公告)号：US20110259924A1

    公开(公告)日：2011-10-27

    申请号：US13106206

    申请日：2011-05-12

    申请人： Tobias METZ ,  Peter KOLTAY

    发明人： Tobias METZ ,  Peter KOLTAY

    IPC分类号： B22D41/50 ,  B01L3/00 ,  B41J2/015

    CPC分类号： B41J2/211

    摘要： A device for generating a drop of a primary liquid is described, including: a reservoir fillable with the primary liquid, a pressure generation device for generating a hydraulic pressure on the primary liquid, at least one inlet channel for introducing a secondary fluid, and a channel having a flow cross-section transverse to a main flow direction, wherein the flow cross-section includes a main region and at least one sub-region extending from the main region, designed such that the primary liquid can be held in the main region by capillary forces, and the secondary fluid can be held in the sub-region by capillary forces, wherein the reservoir is fluidically connected to a first end of the channel via an output opening, and the at least one inlet channel is also fluidically connected to the channel, and wherein the pressure generation device is implemented to apply a hydraulic pressure to the primary liquid, whereby the same is moved along the channel and output at a second end of the channel as free-flying drop.

    摘要翻译： 描述了用于产生一次液体的液滴的装置，包括：可用主液体填充的储存器，用于在主液体上产生液压的压力产生装置，用于引入次流体的至少一个入口通道和 所述流路截面包括主区域和从所述主区域延伸的至少一个子区域，其被设计成使得所述主液体能够保持在所述主区域中 通过毛细管力，并且次级流体可以通过毛细管力保持在子区域中，其中储存器经由输出开口流体连接到通道的第一端，并且至少一个入口通道也流体连接到 所述通道，并且其中所述压力发生装置被实施为向所述主要液体施加液压，由此所述压力产生装置沿着所述通道移动并在所述第二端部输出 频道作为自由飞行的下降。

    Microdosing apparatus and method for dosed dispensing of liquids
    7.
    发明授权
    Microdosing apparatus and method for dosed dispensing of liquids 有权
    用于液体配药的微量滴定装置和方法

    公开(公告)号：US07900850B2

    公开(公告)日：2011-03-08

    申请号：US11353681

    申请日：2006-02-14

    申请人： Roland Zengerle ,  Peter Koltay ,  Wolfgang Streule ,  Gerhard Birkle

    发明人： Roland Zengerle ,  Peter Koltay ,  Wolfgang Streule ,  Gerhard Birkle

    IPC分类号： B05B1/30 ,  B05B15/00 ,  B05B1/00 ,  F04B43/12 ,  F04B43/08

    CPC分类号： B01L3/0268 ,  B01L2300/0838 ,  B01L2300/123 ,  B01L2400/0481 ,  Y10S239/12

    摘要： A microdosing apparatus and method include a fluid conduit having a flexible tube with a first end for connecting to a fluid reservoir and a second end where an outlet opening is located. An actuating device with a displacer with an adjustable stroke is provided, by which the volume of a portion of the flexible tube can be changed to thereby dispense liquid as free flying droplets or as a free flying jet at the outlet opening by moving the displacer between a first end position and a second end position, whereby the tube is partly compressed in the first or the second end position.

    摘要翻译： 微量给药装置和方法包括具有柔性管的流体导管，其具有用于连接到流体储存器的第一端和位于出口开口的第二端。 提供了具有可调节行程的置换器的致动装置，通过该致动装置可以改变柔性管的一部分的体积，从而通过在排出口处移动排液器而将液体作为自由飞行液滴分配或作为自由飞行射流 第一端部位置和第二端部位置，由此在第一端部或第二端部位置部分地压缩管件。

    Device and method for dosing small amounts of liquid
    8.
    发明授权
    Device and method for dosing small amounts of liquid 有权
    用于给予少量液体的装置和方法

    公开(公告)号：US07396510B2

    公开(公告)日：2008-07-08

    申请号：US10250607

    申请日：2002-01-10

    申请人： Roland Zengerle ,  Peter Koltay

    发明人： Roland Zengerle ,  Peter Koltay

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0268 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2400/0487 ,  Y10T436/2575

    摘要： A microdosage device comprises a media reservoir used for accommodating a liquid to be dosed, a nozzle connected via a connecting channel to the media reservoir and adapted to be filled via said connecting channel with the liquid to be dosed, and a drive unit for applying, when actuated, to a liquid contained in the media reservoir and in the nozzle a force of such a nature that a substantially identical pressure will be exerted on said liquid contained in the media reservoir and in the nozzle. Flow resistances of the connecting channel and of the nozzle are dimensioned such that, in response to an actuation of the drive unit, a volumetric flow in the connecting channel will be small in comparison with a volumetric flow in the nozzle, said volumetric flow in the nozzle causing an ejection of the liquid to be dosed from an ejection opening of the nozzle.

    摘要翻译： 微型剂量装置包括用于容纳待定量液体的介质储存器，经由连接通道连接到介质储存器并适于经由所述连接通道与待计量液体填充的喷嘴;以及驱动单元， 当被驱动时，包含在介质容器中和在喷嘴中的液体具有这样一种性质的力，使得基本上相同的压力将被施加在容纳在介质储存器和喷嘴中的所述液体上。 连接通道和喷嘴的流动阻力尺寸使得响应于驱动单元的致动，与喷嘴中的体积流相比，连接通道中的体积流量将小， 喷嘴引起从喷嘴的喷射口喷射的液体。

    Pipette tip, pipetting device, pipette tip actuating device and method for pipetting in the NL range
    9.
    发明授权
    Pipette tip, pipetting device, pipette tip actuating device and method for pipetting in the NL range 有权
    移液器吸头，移液装置，移液管吸头驱动装置以及在NL范围内移液的方法

    公开(公告)号：US08071049B2

    公开(公告)日：2011-12-06

    申请号：US11351910

    申请日：2006-02-10

    申请人： Peter Koltay ,  Wolfgang Streule

    发明人： Peter Koltay ,  Wolfgang Streule

    IPC分类号： B01L3/02 ,  B01L5/00

    CPC分类号： B01L3/0268 ,  B01L3/0275 ,  B01L2300/0832 ,  B01L2300/123 ,  B01L2400/0481

    摘要： A changeable pipette tip includes a first end having a fluid opening and a second end having a pipe elastic in the radial direction having an orifice. The orifice and the fluid opening are in fluid connection. The first end is designed to be coupled to a matching coupling unit of a pipetting unit such that liquid may be sucked into the fluid area through the orifice by an actuating unit in the pipetting unit. In order to eject liquid as free-flying droplets or as a jet from the orifice of the pipe elastic in the radial direction, a volume change of a portion of the pipe elastic in the radial direction is effected.

    摘要翻译： 一种可更换的吸头包括具有流体开口的第一端和具有径向弹性的管的第二端，该第二端具有孔口。 孔口和流体开口处于流体连接状态。 第一端被设计成耦合到移液单元的匹配联接单元，使得液体可以通过移液单元中的致动单元通过孔口被吸入流体区域。 为了将液体作为自由飞散的液滴或作为射流从弹性孔的径向喷射出来，弹性体的一部分在径向方向上的体积变化。