Degradable biocompatible block copolymer
    4.
    发明授权
    Degradable biocompatible block copolymer 有权
    可降解的生物相容性嵌段共聚物

    公开(公告)号:US08362159B2

    公开(公告)日:2013-01-29

    申请号:US12940786

    申请日:2010-11-05

    IPC分类号: C08G63/08

    摘要: Disclosed is a biocompatible block copolymer containing the polycondensation product of a diol and an additional component selected from the group of the same diol, an α,ω-dihydroxy-polyester or an α,ω-dihydroxy-polyether. Also disclosed are a medical implant containing the block copolymer, the use of said block copolymer for the production of a medical implant, a diol and a method for the production thereof. The diol may be obtained by transesterification of α,ω-dihydroxy-[(oligo(3-(R)-hydroxybutyrate)-ethylene-oligo-(3-(R)-hydroxybutyrate)] with diglycolide. Transesterification is carried out, preferably, in the presence of a catalyst.

    摘要翻译: 公开了含有二醇和选自相同的二醇,α,ω-二羟基 - 聚酯或α,ω-二羟基 - 聚醚的另外组分的缩聚产物的生物相容性嵌段共聚物。 还公开了含有嵌段共聚物的医疗植入物,所述嵌段共聚物用于制备医疗植入物,二醇及其制备方法的用途。 二醇可以通过α,ω-二羟基 - [(低级(3-(R) - 羟基丁酸酯) - 乙烯 - 低聚 - (3-(R) - 羟基丁酸酯)]与二甘醇二酯的酯交换反应来进行,优选进行酯交换 ,在催化剂的存在下。

    Degradable Biocompatible Block Copolymer
    7.
    发明申请
    Degradable Biocompatible Block Copolymer 有权
    可降解生物相容性嵌段共聚物

    公开(公告)号:US20110093066A1

    公开(公告)日:2011-04-21

    申请号:US12940786

    申请日:2010-11-05

    IPC分类号: A61F2/24 C08L67/00 C08G63/06

    摘要: Disclosed is a biocompatible block copolymer containing the polycondensation product of a diol and an additional component selected from the group of the same diol, an α,ω-dihydroxy-polyester or an α,ω-dihydroxy-polyether. Also disclosed are a medical implant containing the block copolymer, the use of said block copolymer for the production of a medical implant, a diol and a method for the production thereof. The diol may be obtained by transesterification of α,ω-dihydroxy-[(oligo(3-(R)-hydroxybutyrate)-ethylene-oligo-(3-(R)-hydroxybutyrate)] with diglycolide. Transesterification is carried out, preferably, in the presence of a catalyst.

    摘要翻译: 公开了含有二醇和选自相同的二醇,α,ω-二羟基 - 聚酯或α,ω-二羟基 - 聚醚的另外组分的缩聚产物的生物相容性嵌段共聚物。 还公开了含有嵌段共聚物的医疗植入物,所述嵌段共聚物用于制备医疗植入物,二醇及其制备方法的用途。 二醇可以通过α,ω-二羟基 - [(低级(3-(R) - 羟基丁酸酯) - 乙烯 - 低聚 - (3-(R) - 羟基丁酸酯)]与二甘醇二酯的酯交换反应来进行,优选进行酯交换 ,在催化剂的存在下。

    Degradable biocompatible block copolymer
    9.
    发明申请
    Degradable biocompatible block copolymer 审中-公开
    可降解的生物相容性嵌段共聚物

    公开(公告)号:US20060178477A1

    公开(公告)日:2006-08-10

    申请号:US10564360

    申请日:2004-07-06

    IPC分类号: C08G18/32 C08G64/00 A61F2/00

    摘要: Disclosed is a biocompatible block copolymer containing the polycondensation product of a diol and an additional component selected from the group of the same diol, an α,ω-dihydroxy-polyester or an α,ω-dihydroxy-polyether. Also disclosed are a medical implant containing the block copolymer, the use of said block copolymer for the production of a medical implant, a diol and a method for the production thereof. The diol may be obtained by transesterification of α,ω-dihydroxy-[oligo(3-(R)-hydroxybutyrate)-ethylene-oligo-(3-(R)-hydroxybutyrate)] with diglycolide. Transesterification is carried out, preferably, in the presence of a catalyst.

    摘要翻译: 公开了含有二醇和选自相同二醇,α,ω-二羟基 - 聚酯或α,ω-二羟基 - 聚醚的另外组分的缩聚产物的生物相容性嵌段共聚物。 还公开了含有嵌段共聚物的医疗植入物,所述嵌段共聚物用于制备医疗植入物,二醇及其制备方法的用途。 二醇可以通过α,ω-二羟基 - [低聚(3-(R) - 羟基丁酸酯) - 乙烯 - 低聚 - (3-(R) - 羟基丁酸酯)]与二甘醇二酯的酯交换得到。 优选在催化剂存在下进行酯交换反应。