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    SYSTEMS AND METHODS FOR MONITORING BEHAVIOR INFORMATICS
    2.
    发明申请
    SYSTEMS AND METHODS FOR MONITORING BEHAVIOR INFORMATICS 审中-公开
    用于监测行为信息的系统和方法

    公开(公告)号：US20030083822A2

    公开(公告)日：2003-05-01

    申请号：US10147336

    申请日：2002-05-15

    Applicant: PsychoGenics, Inc.

    Inventor： Daniela Brunner ,  Vijay Gondhalekar ,  Emer Leahy

    IPC: G06F017/60 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50

    CPC classification number: G06Q50/22 ,  A01K1/031 ,  G06F19/00 ,  G06F19/18 ,  G06F19/24 ,  G06F19/28 ,  G06F19/3456 ,  G16H10/20 ,  G16H10/60 ,  G16H15/00 ,  G16H50/70

    Abstract: Abstract of DisclosureA system and method used to assess animal behavior includes a module having sensors that collects a variety of physical and biological data from a test subject. Interpretation of the data is provided to assess the test subject's behavior, neurology, biochemistry and physiology. The module is useful in observing the effects of a drug on the test animal and providing information on the drug's signature. Another advantage is module's portability that allows it to be used in standard laboratory cages. This portability allows the animal to be tested in its own habitat, that can reduce any erroneous data due to stressing the animal when removed to a test cage. Additionally, the module's design allows for parallel data collection and interpretation from several laboratory animals undergoing different experiments. Multi-dimensional modeling of the test subject based the system's interpretation of the data allows pattern recognition of the drug signature, and predictive drug analysis.

    Abstract translation: 公开摘要用于评估动物行为的系统和方法包括具有从测试对象收集各种物理和生物数据的传感器的模块。 提供数据的解释以评估测试对象的行为，神经学，生物化学和生理学。 该模块可用于观察药物对测试动物的影响并提供有关药物特征的信息。 另一个优点是模块的可移植性，允许其在标准实验室网箱中使用。 这种携带性允许动物在自己的栖息地进行测试，这可以减少由于在移动到测试笼时对动物施加压力的任何错误数据。 此外，该模块的设计允许来自经历不同实验的几个实验动物的并行数据收集和解释。 基于系统对数据的解释的测试对象的多维建模允许模式识别药物特征和预测药物分析。

    Treatment of Motor and Movement Disorder Side Effects Associated with Parkinson's Disease Treatments
    4.
    发明申请
    Treatment of Motor and Movement Disorder Side Effects Associated with Parkinson's Disease Treatments 审中-公开
    治疗与帕金森病相关的运动障碍和运动障碍副作用

    公开(公告)号：US20130331399A1

    公开(公告)日：2013-12-12

    申请号：US13911639

    申请日：2013-06-06

    Applicant: Psychogenics, Inc.

    Inventor： Emer Leahy ,  Bavani Shankar

    IPC: A61K31/496 ,  A61K31/198

    Abstract: This invention provides methods of treating motor disorder side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of eltoprazine or a pharmaceutically acceptable acid addition salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with Parkinson's disease treatments, and effective doses of eltoprazine or a pharmaceutically acceptable acid addition salt thereof.

    Abstract translation: 本发明提供了通过施用埃坡替拉嗪或其药学上可接受的酸加成盐来治疗与左旋多巴给予帕金森病患者相关的运动障碍副作用的方法。 特别地，本发明提供了减少与帕金森病治疗相关的运动障碍的方法，以及有效剂量的依托拉嗪或其药学上可接受的酸加成盐。

    Treatment for Neurological and Mental Disorders
    6.
    发明申请
    Treatment for Neurological and Mental Disorders 审中-公开

    公开(公告)号：US20180228799A1

    公开(公告)日：2018-08-16

    申请号：US15951684

    申请日：2018-04-12

    Applicant: PSYCHOGENICS, INC.

    Inventor： Emer Leahy ,  Mark Day

    IPC: A61K31/496 ,  A61K47/12 ,  A61K47/36 ,  A61K47/02 ,  A61K9/00 ,  A61K47/10

    CPC classification number: A61K31/496 ,  A61K9/0053 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/36

    Abstract: Methods for treating neurological or mental disorders in humans and the symptoms associated therewith are provided by administering eltoprazine and/or related compounds. In some embodiments, specific symptoms are treated by administering eltoprazine and/or a related compound in an effective amount to ameliorate the symptoms. Of particular significance are symptoms that are associated with cognitive dysfunction where eltoprazine will improve the symptoms and the disorder associated with that symptom. Of particular interest are non-ADHD-associated inattention, hyperactivity and impulsiveness. The methods provided herein are especially useful for improving functional recovery after CNS injury such as stroke where improved cognitive function will facilitate the acquisition of learning and memory of rehabilitative tasks.

    Treatment for Neurological and Mental Disorders
    7.
    发明申请
    Treatment for Neurological and Mental Disorders 审中-公开

    公开(公告)号：US20160067244A1

    公开(公告)日：2016-03-10

    申请号：US14945013

    申请日：2015-11-18

    Applicant: Psychogenics, Inc.

    Inventor： Emer Leahy ,  Mark Day

    IPC: A61K31/496 ,  A61K47/12 ,  A61K47/36 ,  A61K47/10 ,  A61K9/00 ,  A61K47/02

    CPC classification number: A61K31/496 ,  A61K9/0053 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/36

    Abstract: Methods for treating neurological or mental disorders in humans and the symptoms associated therewith are provided by administering eltoprazine and/or related compounds. In some embodiments, specific symptoms are treated by administering eltoprazine and/or a related compound in an effective amount to ameliorate the symptoms. Of particular significance are symptoms that are associated with cognitive dysfunction where eltoprazine will improve the symptoms and the disorder associated with that symptom. Of particular interest are non-ADHD-associated inattention, hyperactivity and impulsiveness. The methods provided herein are especially useful for improving functional recovery after CNS injury such as stroke where improved cognitive function will facilitate the acquisition of learning and memory of rehabilitative tasks.

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