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    Heterocyclymethylamino derivatives of cyclobutene-3,4-diones
    1.
    发明授权
    Heterocyclymethylamino derivatives of cyclobutene-3,4-diones 失效
    环丁烯-3,4-二酮的杂环甲基氨基衍生物

    公开(公告)号：US5872139A

    公开(公告)日：1999-02-16

    申请号：US873132

    申请日：1997-06-10

    Applicant: David R. Herbst ,  John A. Butera ,  Russell F. Graceffa

    Inventor： David R. Herbst ,  John A. Butera ,  Russell F. Graceffa

    IPC: C07D213/38 ,  C07D307/81 ,  C07D307/82 ,  A61K31/34 ,  A61K31/44 ,  C07D213/50

    CPC classification number: C07D307/82 ,  C07D213/38 ,  C07D307/81

    Abstract: The compounds of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are, independently, hydrogen, straight chain alkyl, branched chain alkyl, cycloalkyl, bicycloalkyl or aralkyl, wherein the aromatic moiety of the aralkyl group may be optionally substituted with one to three straight chain alkyl, halogen, nitro, cyano, alkoxy, alkoxycarbonyl, trifluoromethyl or trifluoromethoxy groups; R.sub.3 is hydrogen, formyl, alkanoyl, alkenoyl, alkylsulfonyl, aroyl, arylalkenoyl, arylsulfonyl, arylalkanoyl or arylalkylsulfonyl; A is selected from the group consisting of: ##STR2## wherein n is 0 or 1; R.sub.4, R.sub.5 and R.sub.6 are, independently, cyano, nitro, amino, alkyl, perfluoroalkyl, alkoxy, perfluoroalkoxy, alkylamino, dialkylamino, sulfamyl, alkylsulfonamido, arylsulfonamido, alkylcarboxamido, arylcarboxamido, alkanoyl, alkylsulfonyl, perfluoroalkylsulfonyl, arylsulfonyl, chloro, bromo, fluoro, iodo, 1-imidazolyl, carboxyl or hydrogen; or a pharmaceutically acceptable salt thereof, relax smooth muscles.

    Abstract translation: 下式的化合物：其中R 1和R 2独立地是氢，直链烷基，支链烷基，环烷基，双环烷基或芳烷基，其中芳烷基的芳族部分可以任选地被一个 三个直链烷基，卤素，硝基，氰基，烷氧基，烷氧基羰基，三氟甲基或三氟甲氧基; R 3是氢，甲酰基，烷酰基，烯酰基，烷基磺酰基，芳酰基，芳基烯酰基，芳基磺酰基，芳基烷酰基或芳基烷基磺酰基; A选自由以下组成的组： 其中n为0或1; R 4，R 5和R 6独立地是氰基，硝基，氨基，烷基，全氟烷基，烷氧基，全氟烷氧基，烷基氨基，二烷基氨基，氨基磺酰基，烷基磺酰氨基，芳基磺酰氨基，烷基羧酰氨基，芳基羧酰氨基，烷酰基，烷基磺酰基，全氟烷基磺酰基，芳基磺酰基，氯，溴，氟 ，碘，1-咪唑基，羧基或氢; 或其药学上可接受的盐，使平滑肌松弛。

    Method and means of reading punched data tape
    2.
    发明授权
    Method and means of reading punched data tape 失效
    阅读穿孔数据磁带的方法和手段

    公开(公告)号：US4373114A

    公开(公告)日：1983-02-08

    申请号：US64257

    申请日：1979-08-06

    Applicant: Wayne R. Herbst

    Inventor： Wayne R. Herbst

    IPC: G06K7/10 ,  G08C9/06

    CPC classification number: G06K7/10851

    Abstract: A photoelectric circuit for reading punched data tape wherein the circuit compensates for variations in phototransistors and light emitting diodes, dust accumulation and degradation of the light emitting diodes by comparing the light transmitted through a punched section of the tape to the light transmitted through a solid section of the tape.

    Abstract translation: 一种用于读取穿孔数据带的光电路，其中电路补偿光电晶体管和发光二极管的变化，通过将通过穿孔的穿孔部分透射的光与通过固体部分透射的光进行比较来发光二极管的灰尘积聚和劣化 的磁带。

    Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones
    4.
    发明授权
    Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones 失效
    取代的环丁基-3,4-二酮的N-芳基甲基氨基衍生物

    公开(公告)号：US5780505A

    公开(公告)日：1998-07-14

    申请号：US889166

    申请日：1997-07-07

    Applicant: Madelene M. Antane ,  David R. Herbst ,  Geraldine R. McFarlane ,  Eric G. Gundersen ,  Bradford H. Hirth ,  Dominick A. Quagliato ,  Russell F. Graceffa ,  John A. Butera

    Inventor： Madelene M. Antane ,  David R. Herbst ,  Geraldine R. McFarlane ,  Eric G. Gundersen ,  Bradford H. Hirth ,  Dominick A. Quagliato ,  Russell F. Graceffa ,  John A. Butera

    IPC: C07C225/20 ,  C07C233/41 ,  C07C255/58 ,  C07C271/24 ,  A61K31/275

    CPC classification number: C07C255/58 ,  C07C225/20 ,  C07C233/41 ,  C07C271/24 ,  C07C2101/04 ,  C07C2101/08

    Abstract: The compounds of the formula: ##STR1## wherein R.sub.1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R.sub.7 and R.sub.8 are, independently, hydrogen or an acyl substituent selected from the group consisting of formyl, alkanoyl, alkenoyl, alkoxycarbonyl, alkylsulfonyl, aroyl, arylalkenoyl, arylsulfonyl, arylalkanoyl or arylalkylsulfonyl; A is a phenyl group with either two or three substituents of the following formula: ##STR2## wherein the positions of substitution are R.sub.2,R.sub.3 -, R.sub.2,R.sub.4 -, R.sub.2,R.sub.5 -, R.sub.2,R.sub.6 -, R.sub.3,R.sub.4 -, R.sub.3,R.sub.5 -, and R.sub.2,R.sub.4,R.sub.6 - and R.sub.2 is methyl, ethyl, fluoro, chloro, methoxy or trifluoromethyl; R.sub.3 is methyl, ethyl, fluoro, chloro, methoxy or trifluoromethyl; R.sub.4 is methyl, fluoro, bromo, methoxy or cyano; R.sub.5 is methyl, fluoro, chloro, methoxy, cyano or trifluoromethyl; R.sub.6 is methyl, fluoro, chloro, or methoxy; or a pharmaceutically acceptable salt thereof, relax smooth muscles.

    Abstract translation: 下式的化合物：其中R 1是直链烷基，支链烷基，环烷基，羟基烷基，氟烷基或多氟烷基; R 7和R 8独立地是氢或选自甲酰基，烷酰基，烯酰基，烷氧基羰基，烷基磺酰基，芳酰基，芳基烯酰基，芳基磺酰基，芳基烷酰基或芳基烷基磺酰基的酰基取代基。 A是具有下式的两个或三个取代基的苯基：其中取代的位置是R2，R3-，R2，R4-，R2，R5-，R2，R6-，R3，R4-， R 3，R 5和R 2，R 4，R 6和R 2是甲基，乙基，氟，氯，甲氧基或三氟甲基; R3是甲基，乙基，氟，氯，甲氧基或三氟甲基; R4是甲基，氟，溴，甲氧基或氰基; R5是甲基，氟，氯，甲氧基，氰基或三氟甲基; R6是甲基，氟，氯或甲氧基; 或其药学上可接受的盐，使平滑肌松弛。

    In-line blender
    6.
    发明授权
    In-line blender 失效
    在线搅拌机

    公开(公告)号：US4123178A

    公开(公告)日：1978-10-31

    申请号：US779872

    申请日：1977-03-21

    Applicant: Ronald N. Salzman ,  Norman R. Herbst

    Inventor： Ronald N. Salzman ,  Norman R. Herbst

    IPC: B01F5/06 ,  B01F5/00

    CPC classification number: B01F5/0656

    Abstract: An in-line blender is provided for mixing a single fluid or blending it with at least one other substance. The blender includes a conduit having a hollow interior disposed about a central axis and a shaft extending longitudinally through the conduit along the central axis. The blender also includes a plurality of stationary mixing stages extending in series along the central axis with each of the mixing stages defining a plurality of spiral channels within the hollow interior of the conduit. Each of the mixing stages includes a plurality of distinct segments extending in series along the central axis. The blender further includes means for adjusting both the angular and the axial position of each of the segments with respect to adjacent segments along the shaft. The in-line blender is assembled by securing a retaining device to one end of the shaft, placing a plurality of mixing elements on the shaft in sliding engagement therewith, and positioning each mixing element at a desired angular and axial position on the shaft. A holding device is secured on a second end of the shaft so as to hold the mixing element in compression between the holding device and the retaining device. The shaft and mixing elements are then placed within a conduit and secured therein so as to prevent relative axial movement therebetween.

    Abstract translation: 提供了一种在线混合器，用于混合单一流体或将其与至少一种其它物质混合。 搅拌器包括具有围绕中心轴线设置的中空内部的管道和沿着中心轴线纵向延伸通过导管的轴。 搅拌器还包括沿着中心轴线串联延伸的多个固定混合台，每个混合阶段在导管的中空内部内限定多个螺旋通道。 每个混合级包括沿着中心轴线串联延伸的多个不同部分。 搅拌器还包括用于相对于沿着轴的相邻段来调节每个段的角度和轴向位置的装置。 通过将保持装置固定到轴的一端来组装直列式搅拌器，将多个混合元件放置在轴上与其滑动接合，并将每个混合元件定位在轴上期望的角度和轴向位置。 保持装置固定在轴的第二端上，以便在保持装置和保持装置之间保持混合元件的压缩。 然后将轴和混合元件放置在导管内并固定在其中，以防止它们之间的相对轴向移动。

    Apparatus and method for recording and reproducing digital-data
    7.
    发明授权
    Apparatus and method for recording and reproducing digital-data 失效
    用于记录和复制数字数据的装置和方法

    公开(公告)号：US4001884A

    公开(公告)日：1977-01-04

    申请号：US594835

    申请日：1975-07-10

    Applicant: Wayne R. Herbst ,  Paul L. Mika

    Inventor： Wayne R. Herbst ,  Paul L. Mika

    IPC: G11B20/10 ,  G11B20/12 ,  G11B20/14 ,  G11B20/16 ,  G11B5/00

    CPC classification number: G11B20/1419 ,  G11B20/10009 ,  G11B20/1202 ,  G11B20/1426 ,  G11B20/16

    Abstract: A series of digital words are demultiplexed into two groups and recorded on parallel tracks of a magnetic tape. The digital information is phase encoded upon the two tape channels and during playback the magnetic flux reversals on each channel are separately detected. The peak level of the detected signal is sensed and a peak signal pulse generated corresponding to the occurrence of the peak of the detected signal. Means are additionally included for setting the minimum threshold of the incoming signal necessary to generate a signal pulse so as to provide a level of immunity to system noise. The peak signal pulses are decoded to reconstruct the original data signal and a clocking signal. The data from each of the channel decoders is clocked into respective channel shift registers and multiplexed into its original data word arrangement.

    Filter and method of forming a filter
    9.
    发明申请
    Filter and method of forming a filter 审中-公开
    过滤器和形成过滤器的方法

    公开(公告)号：US20050252851A1

    公开(公告)日：2005-11-17

    申请号：US10848482

    申请日：2004-05-17

    Applicant: Nicholas Mann ,  R. Herbst ,  Vadim Kochergin ,  Tammy Trowbridge

    Inventor： Nicholas Mann ,  R. Herbst ,  Vadim Kochergin ,  Tammy Trowbridge

    IPC: B01D29/50

    CPC classification number: B01D39/2051 ,  B01D39/2079

    Abstract: A filter and method of forming a filter is described and which includes a porous inorganic substrate having a plurality of pores, and which permits the passage of a fluid therethrough, and a ceramic filtration media formed of particles having a particle size which permits the ceramic filtration media to be embedded in at least some of the porous inorganic substrate and positioned at and/or below the top surface of the inorganic substrate.

    Abstract translation: 描述了形成过滤器的过滤器和方法，其包括具有多个孔的多孔无机基材，并且允许流体通过其中，并且由具有允许陶瓷过滤的粒径的颗粒形成的陶瓷过滤介质 介质被嵌入到至少一些多孔无机基材中并且定位在无机基材的顶表面的和/或下方。

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