公开(公告)号：US20220249471A1

公开(公告)日：2022-08-11

申请号：US17618700

申请日：2020-06-12

申请人： Lisa R. YOUNG ,  The Regents of the University of California ,  Children's Hospital of Philadelphia

发明人： Xin SUN ,  Jinhao XU ,  Lisa YOUNG

IPC分类号： A61K31/499 ,  A61P11/00 ,  A61K9/00 ,  A61K45/06 ,  A61K9/16

摘要： The present disclosure provides a novel animal model of NEHI, and method of preventing and/or treating a pulmonary disease, particularly the lung-based complications in NEHI, such as pulmonary edema, by targeting the PNEC product, such as the CGRP signaling. Also disclosed is the pharmaceutical composition for preventing and/or treating a pulmonary edema and/or other pulmonary disease, particularly, NEHI, comprising one or more CGRP signaling antagonist and/or inhibitor of the present disclosure.

公开(公告)号：US10344590B1

公开(公告)日：2019-07-09

申请号：US15348088

申请日：2016-11-10

申请人： Allen R. Young ,  Brad Reeves

发明人： Allen R. Young ,  Brad Reeves

IPC分类号： E21B47/18 ,  E21B47/022

摘要： The present invention is a method and apparatus used to transmit information to the surface from a subsurface location during the process of drilling a bore hole comprising a pressure pulse generator or “pulser” coupled to a sensor package, a controller, an active electromagnetic system for subsurface collision avoidance, and a battery power source all of which reside inside a short section of drill pipe close to the bit at the bottom of the bore hole being drilled wherein the apparatus or “MWD Tool” can be commanded from the surface to make a measurement of desired parameters and transmit this information to the surface by encoding data in pressure pulses generated by a pulser valve that includes a stator and a rotor which may be open and closed to create pressure pulses.

公开(公告)号：US09290850B2

公开(公告)日：2016-03-22

申请号：US14069109

申请日：2013-10-31

申请人： Donovan L. Erickson ,  Roy A. Johnson ,  Matthew Ryan LaBrosse ,  Paul R. Young

发明人： Donovan L. Erickson ,  Roy A. Johnson ,  Matthew Ryan LaBrosse ,  Paul R. Young

IPC分类号： C23F11/14 ,  C23F11/08 ,  C23F11/173 ,  C23F11/18

CPC分类号： C23F11/144 ,  C23F11/08 ,  C23F11/173 ,  C23F11/18 ,  C23F11/187

摘要： Methods for inhibiting the corrosion of metals in contact with an aqueous system are provided. The method of inhibiting corrosion includes maintaining effective amounts of (1) an amino acid-based polymer, such as a polyaspartic acid compound, and (2) a dispersible and/or soluble tin compound in the aqueous system. The corrosion inhibiting components of the treatment may be added simultaneously or separately into the water of the aqueous system, i.e., provided either in a single treatment product or as separate products. Such a corrosion inhibiting method may optionally also include adding a polycarboxylic acid chelating agent and/or a carboxylate/sulfonate functional copolymer to the aqueous system.

摘要翻译： 提供了用于抑制与水系统接触的金属腐蚀的方法。 抑制腐蚀的方法包括维持有效量的（1）氨基酸类聚合物如聚天冬氨酸化合物，和（2）在水性体系中的可分散和/或可溶的锡化合物。 处理的腐蚀抑制组分可以同时或分别加入到含水体系的水中，即提供在单一处理产物中或作为单独的产物。 这种腐蚀抑制方法还可以任选地包括向水性体系中加入多元羧酸螯合剂和/或羧酸盐/磺酸盐官能共聚物。

公开(公告)号：US09102417B1

公开(公告)日：2015-08-11

申请号：US12965527

申请日：2010-12-10

申请人： Donald R. Young

发明人： Donald R. Young

IPC分类号： G08B21/00 ,  B64D45/00

CPC分类号： B64D45/00 ,  A61B5/18 ,  A61B5/6814 ,  A61B2503/22 ,  A61B2560/0242 ,  A61B2560/0252 ,  A61B2560/0257 ,  B64D2045/004 ,  B64D2045/0055 ,  B64D2045/0085 ,  G07C5/085

摘要： Method and apparatus for monitoring a vehicle. An apparatus comprises a sensor system and a computer system. The sensor system is associated with a number of human operators of a vehicle and a number of components in the vehicle. The sensor system is configured to generate physiological data for the number of human operators. The computer system is configured to receive the physiological data; determine whether the physiological data is within a level for a desired level of performance for operating the vehicle based on a policy; and perform a number of actions to maintain the desired level of performance for operating the vehicle in response to the physiological data not being within the level for the desired level of performance.

摘要翻译： 车辆监控方法及装置。 一种装置包括传感器系统和计算机系统。 传感器系统与车辆的许多人操作者和车辆中的多个部件相关联。 传感器系统被配置为生成人类操作者数量的生理数据。 计算机系统被配置为接收生理数据; 基于策略来确定生理数据是否在用于操作车辆的期望水平的水平之内; 并且执行多个动作以响应于生理数据不在所期望的性能水平的水平内来维持用于操作车辆的期望的性能水平。

公开(公告)号：US20140129577A1

公开(公告)日：2014-05-08

申请号：US13672092

申请日：2012-11-08

申请人： James R. Young, JR. ,  Nathan Fong ,  Henrik Steen ,  Vas Sudanagunta

发明人： James R. Young, JR. ,  Nathan Fong ,  Henrik Steen ,  Vas Sudanagunta

IPC分类号： G06F17/30

CPC分类号： H04L67/02 ,  G06F17/3089 ,  H04L67/2823

摘要： There is provided a system and method for optimized filtered data feeds to capture data and send to multiple destinations. There is provided a system comprising a memory and a processor. The memory has a database associating data feed patterns to one or more of a plurality of destinations. The processor captures data from a data feed having a data feed destination, stores the data in the memory, compares the data feed with the data feed patterns in the database to determine matched patterns, retrieves one or more destinations associated with the matched patterns, and sends the data to the data feed destination and the retrieved destinations. There is also provided a system comprising data feed sources, destinations, a network connected to the data feed sources and the destinations, and a server configured to intercept and route network traffic on the network, the server including a memory and a processor.

摘要翻译： 提供了一种用于优化过滤数据馈送以捕获数据并发送到多个目的地的系统和方法。 提供了一种包括存储器和处理器的系统。 存储器具有将数据馈送模式与多个目的地中的一个或多个相关联的数据库。 处理器从具有数据馈送目的地的数据馈送器捕获数据，将数据存储在存储器中，将数据馈送与数据库中的数据馈送模式进行比较以确定匹配的模式，检索与匹配模式相关联的一个或多个目的地，以及 将数据发送到数据馈送目的地和检索到的目的地。 还提供了一种系统，包括数据馈送源，目的地，连接到数据馈送源和目的地的网络，以及被配置为拦截和路由网络上的网络流量的服务器，该服务器包括存储器和处理器。

公开(公告)号：US08575480B2

公开(公告)日：2013-11-05

申请号：US13097199

申请日：2011-04-29

申请人： Dennis R. Young

发明人： Dennis R. Young

IPC分类号： H05K5/00

CPC分类号： H05K5/0069

摘要： A connection assembly for securing electrical components used with power equipment comprises a housing and connector cover forming an upper arrangement of the connection assembly. The housing and connector cover form a cavity therebetween for supporting electronics disposed within the cavity. The connection assembly also comprises a lower arrangement used to secure the connection assembly to a surface of a power equipment device and a hinge assembly that forms a rotational connection between the upper arrangement and the lower arrangement.

摘要翻译： 用于固定与电力设备一起使用的电气部件的连接组件包括形成连接组件的上部布置的壳体和连接器盖。 壳体和连接器盖在它们之间形成一个空腔，用于支撑设置在空腔内的电子装置。 连接组件还包括用于将连接组件固定到动力设备装置的表面的下部装置和形成上部装置和下部装置之间的旋转连接的铰链组件。

公开(公告)号：US20130281399A1

公开(公告)日：2013-10-24

申请号：US13832970

申请日：2013-03-15

申请人： Kevin G. McLure ,  Peter R. Young

发明人： Kevin G. McLure ,  Peter R. Young

IPC分类号： C07D239/91 ,  C07D401/10 ,  C07D403/10 ,  C07D401/04 ,  A61K31/519 ,  C07D471/04 ,  C07D401/12 ,  C07D409/12 ,  C07D403/12 ,  A61K31/551 ,  C07D401/14 ,  A61K31/55 ,  A61K45/06 ,  C07D403/04 ,  A61K31/517

CPC分类号： C07D239/91 ,  A61K31/517 ,  A61K31/519 ,  A61K31/55 ,  A61K31/551 ,  A61K45/06 ,  C07D401/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/10 ,  C07D403/12 ,  C07D409/12 ,  C07D471/04

摘要： The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of diseases or disorders that are susceptible to administration of a BET inhibitor.

摘要翻译： 本公开提供了抑制溴结构域和额外末端结构域（BET）蛋白质的非天然存在的多酚化合物。 所公开的组合物和方法可用于治疗和预防易于施用BET抑制剂的疾病或病症。

公开(公告)号：US20130159555A1

公开(公告)日：2013-06-20

申请号：US13331886

申请日：2011-12-20

申请人： Peter D. Rosser ,  Christian Klein ,  Anthony R. Young ,  Arnab Choudhury ,  Alexander D. Tudor

发明人： Peter D. Rosser ,  Christian Klein ,  Anthony R. Young ,  Arnab Choudhury ,  Alexander D. Tudor

IPC分类号： G06F3/00

CPC分类号： G06F3/038 ,  G06F2203/0381

摘要： Input command techniques are described. In one or more implementations, a computing device processes one or more inputs that are received from one or more input sources to determine a command that corresponds to the one or more inputs. The command is exposed to one or more controls that are implemented as software that is executed on the computing device and that have subscribed to the command.

摘要翻译： 描述输入命令技术。 在一个或多个实现中，计算设备处理从一个或多个输入源接收的一个或多个输入以确定对应于一个或多个输入的命令。 命令暴露给一个或多个控制，该控件被实现为在计算设备上执行并已订阅该命令的软件。

公开(公告)号：US08415137B2

公开(公告)日：2013-04-09

申请号：US13274075

申请日：2011-10-14

申请人： Roy Johnson ,  Paul R. Young

发明人： Roy Johnson ,  Paul R. Young

IPC分类号： D06M16/00

CPC分类号： C12P9/00 ,  C12P7/06 ,  Y02E50/17

摘要： The present inventors have surprisingly discovered that phytic acid tenaciously precipitates with soluble metals in food or fuel ethanol-processing fluid, producing insoluble organometallic salt deposit or scale on the processing equipment that must be removed in order to facilitate further ethanol processing. The present invention relates to converting phytic acid salts or phytates to inorganic phosphates to improve metal solubility and reduce deposition within processing equipment.

摘要翻译： 本发明人惊奇地发现植酸与食品或燃料乙醇加工液中的可溶性金属牢固沉淀，在必须除去的加工设备上产生不溶性有机金属盐沉积物或垢，以促进进一步的乙醇加工。 本发明涉及将植酸盐或植酸盐转化为无机磷酸盐以提高金属溶解度并减少加工设备内的沉积。

公开(公告)号：US08250931B2

公开(公告)日：2012-08-28

申请号：US12412610

申请日：2009-03-27

申请人： Paul R. Young ,  Donovan Erickson

发明人： Paul R. Young ,  Donovan Erickson

IPC分类号： G01F1/58 ,  G01F1/64 ,  C23F11/00 ,  C23F11/10 ,  C09K15/06 ,  C09K15/18

CPC分类号： C23F11/10

摘要： The present invention relates to a method for inhibiting in a non-aqueous, non-conductive liquid. The present method also relates to a corrosion inhibitor that can be employed in such a liquid. The method can include measuring or detecting the present corrosion inhibitor with a magnetic flow meter.

摘要翻译： 本发明涉及一种在非水性非导电液体中抑制的方法。 本方法还涉及可用于这种液体中的腐蚀抑制剂。 该方法可以包括用磁流量计测量或检测当前的腐蚀抑制剂。