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公开(公告)号：US20060057599A1
公开(公告)日：2006-03-16
申请号：US11000491
申请日：2004-11-29
申请人： John Dzenitis , Steve Brown , Billy Colston , Dora Gutierrez , Bruce Henderer , Benjamin Hindson , Ramakrishna Madabhushi , Anthony Makarewicz , Don Masquelier , Mary McBride , Thomas Metz , Shanavaz Nasarabadi , Ujwal Setlur , Sally Smith , Kodumudi Venkateswaran
发明人： John Dzenitis , Steve Brown , Billy Colston , Dora Gutierrez , Bruce Henderer , Benjamin Hindson , Ramakrishna Madabhushi , Anthony Makarewicz , Don Masquelier , Mary McBride , Thomas Metz , Shanavaz Nasarabadi , Ujwal Setlur , Sally Smith , Kodumudi Venkateswaran
CPC分类号： G01N1/2202 , G01N1/2211 , G01N15/1459 , G01N35/08 , G01N2001/2217 , Y02A90/26
摘要： An autonomous monitoring apparatus for monitoring air, water, soil, or other substance for bioagents. A collector gathers a quantity of the air, water, soil, or other substance being monitored. A sample preparation system prepares a sample of the selected potential bioagent particles. The sample is analyzed by a system for detecting said bioagents.
摘要翻译： 一种用于监测用于生物制剂的空气，水，土壤或其他物质的自主监测装置。 收集者收集一定数量的被监测的空气，水，土壤或其他物质。 样品制备系统准备所选择的潜在生物标记颗粒的样品。 通过用于检测所述生物代理的系统分析样品。
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公开(公告)号：US20120172692A1
公开(公告)日：2012-07-05
申请号：US12985224
申请日：2011-01-05
IPC分类号： A61B5/1486
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/14865 , A61B5/685
摘要： An analyte monitor having a plurality of fluid paths, each fluid path having a distal opening adapted to be disposed on one side of a stratum corneum layer of a user's skin, a proximal opening adapted to be disposed on another side of the stratum corneum layer and an interior space extending between the distal and proximal openings; a sensing zone in fluid communication with the proximal openings of the fluid paths; sensing fluid extending from the sensing zone into substantially the entire interior space of the fluid paths; and an analyte sensor adapted to detect a concentration of analyte in the sensing fluid within the sensing zone, wherein at least one of the sensing fluid and the analyte sensor comprises a catalyst for mutarotation of glucose. The invention also includes a method of using the monitor.
摘要翻译： 一种具有多个流体路径的分析物监测器，每个流体路径具有适于设置在使用者皮肤的角质层的一侧上的远端开口，适于设置在角质层的另一侧上的近侧开口，以及 在远端和近端开口之间延伸的内部空间; 与流体路径的近端开口流体连通的感测区域; 从所述感测区域延伸到所述流体路径的基本上整个内部空间中的感测流体; 以及分析物传感器，其适于检测所述感测区域内的所述感测流体中的分析物的浓度，其中所述感测流体和所述分析物传感器中的至少一个包括用于葡萄糖变异的催化剂。 本发明还包括使用监视器的方法。
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公开(公告)号：US20060137982A1
公开(公告)日：2006-06-29
申请号：US11359713
申请日：2006-02-21
IPC分类号： B01D57/02
CPC分类号： G01N27/44752 , G01N27/44747
摘要： The invention provides uncharged water-soluble silica-adsorbing polymers for suppressing electroendoosmotic flow and to reduce analyte-wall interactions in capillary electrophoresis. In one aspect of the invention, one or more of such polymers are employed as components of a separation medium for the separation of biomolecules, such as polynucleotides, polysaccharides, proteins, and the like, by capillary electrophoresis. Generally, such polymers are characterized by (i) water solubility over the temperature range between about 20° C. to about 50° C., (ii) concentration in a separation medium in the range between about 0.001% to about 10% (weight/volume), (iii) molecular weight in the range of about 5×103 to about 1×106 daltons, and (iv) absence of charged groups in an aqueous medium having pH in the range of about 6 to about 9. In one embodiment, polymers of the invention are selected from the group consisting of polylactams, such as polyvinylpyrrolidone; N,N-disubstituted polyacrylamides; and N-substituted polyacrylamides. In accordance with the method of the invention, a sufficient amount of polymer adsorbs to the capillary surface to establish a zone of high viscosity that shields the analyte from the wall and impedes the movement of an electrical double layer under an electric field.
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