公开(公告)号：US08425418B2

公开(公告)日：2013-04-23

申请号：US11740807

申请日：2007-04-26

Applicant: Jasjit S. Suri ,  Ramkrishnan Narayanan

Inventor： Jasjit S. Suri ,  Ramkrishnan Narayanan

IPC: A61B8/08

CPC classification number: A61B8/0833

Abstract: A system and method (i.e, utility) are disclosed for positioning a needle in three-dimensions based on patient related statistics for extracting tissue during biopsy procedures. Aspects of the utility can be applied independently or serve as an aid to the urologist when regions of interest are hard to discern in an ultrasound image. Regions of interest that correspond to high cancer risk regions (e.g., statistically) are automatically superimposed on an ultrasound image of a patient in real time. Additionally a statistical map based on one or more demographic parameters of a patient and containing cancer probability locations are also automatically mapped on the ultrasound image in real time displaying potential cancer locations. Aspects of the system are also capable of displaying optimal needle placement positions based on statistical priors and will be able to accurately navigate the needle to that position for biopsy extraction and/or treatment.

Abstract translation: 公开了一种系统和方法（即效用），用于基于用于在活检程序期间提取组织的患者相关统计信息来三维定位针头。 当超声波图像中难以辨别出感兴趣的区域时，可以独立地应用实用方面或作为泌尿科医师的辅助。 对应于高癌症风险区域（例如，统计学）的感兴趣区域被实时地自动叠加在患者的超声图像上。 此外，基于患者的一个或多个人口统计学参数并且包含癌症概率位置的统计图也被实时地自动映射在超声图像上，显示潜在的癌症位置。 该系统的方面还能够基于统计学先验显示最佳的针位置，并且能够精确地将针导向该位置用于活组织检查提取和/或治疗。

公开(公告)号：US20080039723A1

公开(公告)日：2008-02-14

申请号：US11740807

申请日：2007-04-26

Applicant: Jasjit S. Suri ,  Ramkrishnan Narayanan

Inventor： Jasjit S. Suri ,  Ramkrishnan Narayanan

IPC: A61B8/00

CPC classification number: A61B8/0833

Abstract: A system and method (i.e, utility) are disclosed for positioning a needle in three-dimensions based on patient related statistics for extracting tissue during biopsy procedures. Aspects of the utility can be applied independently or serve as an aid to the urologist when regions of interest are hard to discern in an ultrasound image. Regions of interest that correspond to high cancer risk regions (e.g., statistically) are automatically superimposed on an ultrasound image of a patient in real time. Additionally a statistical map based on one or more demographic parameters of a patient and containing cancer probability locations are also automatically mapped on the ultrasound image in real time displaying potential cancer locations. Aspects of the system are also capable of displaying optimal needle placement positions based on statistical priors and will be able to accurately navigate the needle to that position for biopsy extraction and/or treatment.

Abstract translation: 公开了一种系统和方法（即效用），用于基于用于在活检程序期间提取组织的患者相关统计信息来三维定位针头。 当超声波图像中难以辨别出感兴趣的区域时，可以独立地应用实用方面或作为泌尿科医师的辅助。 对应于高癌症风险区域（例如，统计学）的感兴趣区域被实时地自动叠加在患者的超声图像上。 此外，基于患者的一个或多个人口统计学参数并且包含癌症概率位置的统计图也被实时地自动映射在超声图像上，显示潜在的癌症位置。 该系统的方面还能够基于统计学先验显示最佳的针位置，并且能够精确地将针导向该位置用于活组织检查提取和/或治疗。

公开(公告)号：US20090324041A1

公开(公告)日：2009-12-31

申请号：US12359029

申请日：2009-01-23

Applicant: RAMKRISHNAN NARAYANAN ,  YUJUN GUO ,  JASJIT S. SURI

Inventor： RAMKRISHNAN NARAYANAN ,  YUJUN GUO ,  JASJIT S. SURI

IPC: G06K9/00 ,  G06T15/00

CPC classification number: G06T17/20 ,  G06K9/00986 ,  G06K9/6206 ,  G06T7/344 ,  G06T2207/10068 ,  G06T2207/10136 ,  G06T2207/20128 ,  G06T2207/30081

Abstract: A method and apparatus are disclosed for performing software guided prostate biopsy to extract cancerous tissue. The method significantly improves on the current system by accelerating all computations using a graphical processing unit (GPU) keeping the accuracy of biopsy target locations within tolerance. The result is the computation of target locations to guide biopsy using statistical priors of cancers from a large population, as well as based on previous biopsy locations for the same patient, and finally via mapping protocols with predefined needle configurations onto the patient's current ultrasound image.

Abstract translation: 公开了用于执行软件引导的前列腺活检以提取癌组织的方法和装置。 该方法通过使用图形处理单元（GPU）加速所有计算来显着改善，从而将活检目标位置的准确度保持在容差内。 结果是计算目标位置以使用来自大量人群的癌症的统计学先验以及针对同一患者的先前活组织检查位置进行活检，最后通过具有预定义针结构的图像协议到患者的当前超声图像上进行活检。

公开(公告)号：US20110178389A1

公开(公告)日：2011-07-21

申请号：US13035823

申请日：2011-02-25

Applicant: Dinesh Kumar ,  Ramkrishnan Narayanan

Inventor： Dinesh Kumar ,  Ramkrishnan Narayanan

IPC: A61B5/055 ,  A61B8/00

CPC classification number: A61B8/4461 ,  A61B5/055 ,  A61B8/12 ,  A61B8/4254 ,  A61B8/483 ,  A61B8/5238 ,  G06T7/12 ,  G06T7/174 ,  G06T7/33 ,  G06T2207/10088 ,  G06T2207/10136 ,  G06T2207/30081

Abstract: An improved system and method (i.e. utility) for registration of medical images is provided. The utility registers a previously obtained volume (s) onto an ultrasound volume during an ultrasound procedure to produce a multimodal image. The multimodal image may be used to guide a medical procedure. In one arrangement, the multimodal image includes MRI information presented in the framework of a TRUS image during a TRUS procedure.

Abstract translation: 提供了用于医学图像的注册的改进的系统和方法（即实用程序）。 该实用程序在超声程序期间将先前获得的体积记录​​到超声波体积上以产生多峰图像。 多模态图像可用于指导医疗程序。 在一种布置中，多模式图像包括在TRUS过程期间在TRUS图像的框架中呈现的MRI信息。

公开(公告)号：US20090326363A1

公开(公告)日：2009-12-31

申请号：US12434990

申请日：2009-05-04

Applicant: Lu Li ,  Ramkrishnan Narayanan ,  Jasjit S. Suri

Inventor： Lu Li ,  Ramkrishnan Narayanan ,  Jasjit S. Suri

IPC: A61B5/055 ,  A61B8/00 ,  G06K9/00

CPC classification number: A61B8/4461 ,  A61B8/12 ,  A61B8/483 ,  A61B8/5238 ,  G06T7/12 ,  G06T7/174 ,  G06T7/33 ,  G06T2207/10088 ,  G06T2207/10136 ,  G06T2207/30081

Abstract: An improved system and method (i.e. utility) for registration of medical images is provided. The utility registers a previously obtained volume onto an ultrasound volume during an ultrasound procedure to produce a multimodal image. The multimodal image may be used to guide a medical procedure, In one arrangement, the multimodal image includes MRI and/or MRSI information presented in the framework of a TRUS image during a TRUS procedure.

Abstract translation: 提供了用于医学图像的注册的改进的系统和方法（即实用程序）。 该实用程序在超声程序期间将先前获得的体积记录​​到超声波体积上以产生多峰图像。 多模态图像可以用于指导医疗过程。在一种布置中，多模式图像包括在TRUS过程期间在TRUS图像的框架中呈现的MRI和/或MRSI信息。

公开(公告)号：US20100001996A1

公开(公告)日：2010-01-07

申请号：US12380894

申请日：2009-02-25

Applicant: FEIMO SHEN ,  RAMKRISHNAN NARAYANAN ,  JASJIT S. SURI

Inventor： FEIMO SHEN ,  RAMKRISHNAN NARAYANAN ,  JASJIT S. SURI

IPC: G06T15/00

CPC classification number: G06T7/20 ,  G06T7/251 ,  G06T2200/28 ,  G06T2207/10132 ,  G06T2207/30081

Abstract: A method and apparatus using a graphics processing unit (GPU) are disclosed for three-dimensional (3D) imaging and continuously updating organ shape and internal points for guiding targets during motion. It is suitable for image-guided surgery or operations because the speed of guidance is achieved close to video rate. The system incorporates different methods of rigid and non-rigid registration using the parallelism of GPU processing that allows continuous updates in substantially real-time.

Abstract translation: 公开了一种使用图形处理单元（GPU）的方法和装置，用于三维（3D）成像，并且在运动期间不断更新器官形状和内部点以引导目标。 适合图像引导手术或手术，因为指导速度接近视频速度。 该系统采用不同的刚性和非刚性配准方法，使用GPU处理的并行性，可以实时实时连续更新。

公开(公告)号：US20090048515A1

公开(公告)日：2009-02-19

申请号：US11838518

申请日：2007-08-14

Applicant: Jasjit S. Suri ,  Dinesh Kumar ,  Yujun Guo ,  Ramkrishnan Narayanan

Inventor： Jasjit S. Suri ,  Dinesh Kumar ,  Yujun Guo ,  Ramkrishnan Narayanan

IPC: A61B10/02 ,  A61B8/13

CPC classification number: A61B8/12 ,  A61B10/02 ,  A61B2017/00274 ,  A61B2018/00547 ,  A61B2090/367

Abstract: Guided biopsy is a commonly used method to remove suspicious tissues from an internal organ for pathological tests so that malignancy can be established. Provided herein are systems and methods (i.e., utilities) that allow for automated application of one or more predefined biopsy target plans to an acquired medical image including without limitation, an ultrasound prostate image. Due to different shapes and sizes of prostates as well as orientation of prostate with respect to an ultrasound probe during image, acquisition a simple prostate model (e.g., ellipse) with a fixed plan may not be sufficient. Accordingly, it has been determined that a deformable shape model with integrated biopsy target locations/sites may be fit to a prostate image to provide improved automated biopsy targeting.

Abstract translation: 引导活检是一种常用的方法，用于从内部器官中清除可疑组织进行病理检查，以确定恶性。 本文提供了允许将一个或多个预定义的活检目标计划自动应用于所获取的医学图像的系统和方法（即实用程序），包括但不限于超声前列腺图像。 由于在图像期间由于前列腺的不同形状和尺寸以及相对于超声探头的前列腺的取向，所以采集具有固定计划的简单前列腺模型（例如椭圆）可能不足够。 因此，已经确定具有集成活检目标位置/位点的可变形形状模型可以适合于前列腺图像以提供改进的自动活检靶向。