In-line drug delivery device for use with a standard IV administration
set and a method for delivery
    4.
    发明授权
    In-line drug delivery device for use with a standard IV administration set and a method for delivery 失效
    与标准IV给药组一起使用的在线药物递送装置和用于递送的方法

    公开(公告)号:US5547471A

    公开(公告)日:1996-08-20

    申请号:US156347

    申请日:1993-11-22

    摘要: A receptacle (500) is provided for coupling an adaptor (10) having a vial (54) including a beneficial agent to an IV administration set (526). In an embodiment, the receptacle (500) includes an injection site (512) for receiving a cannula (26) from the adaptor (10). A resilient divider (516) separates the receptacle (500) into two sections defined by an upper fitment (508) and a lower fitment (510). A container (520) holding a solution is in fluid communication with the receptacle (500) via an inlet (502). A through bore (518) allows the solution from the container (520) to pass through the resilient divider (516) when the adaptor (10) is removed from the receptacle (500).

    摘要翻译: 提供容器(500),用于将具有包含有益剂的小瓶(54)的适配器(10)连接到IV给药组(526)。 在一个实施例中,容器(500)包括用于从适配器(10)接收套管(26)的注射部位(512)。 弹性分隔器(516)将容器(500)分成由上配件(508)和下配件(510)限定的两个部分。 保持溶液的容器(520)经由入口(502)与容器(500)流体连通。 当适配器(10)从容器(500)移除时,通孔(518)允许来自容器(520)的溶液通过弹性分隔件(516)。

    Adaptor for drug delivery
    6.
    发明授权
    Adaptor for drug delivery 失效
    用于药物输送的适配器

    公开(公告)号:US5385547A

    公开(公告)日:1995-01-31

    申请号:US978555

    申请日:1992-11-19

    摘要: A drug delivery device is provided for coupling a first container including a beneficial agent to a second member. In an embodiment, the device includes a substantially hollow member having a cannula mounted within a wall that divides the substantially hollow member into a first and second section. The first section includes means for receiving at least a portion of a first container. The substantially hollow member includes a wall that defines an exterior of the first section that is substantially flexible. A number of different cannula and flow path structures within the hollow member are possible pursuant to the present invention.

    摘要翻译: 提供了一种药物输送装置,用于将包含有益剂的第一容器与第二构件相结合。 在一个实施例中,该装置包括基本上中空的构件,其具有安装在壁内的套管,其将基本上中空的构件分成第一和第二区段。 第一部分包括用于接收第一容器的至少一部分的装置。 基本上中空的构件包括限定第一部分的外部基本上柔性的壁。 根据本发明,中空构件内的多个不同的插管和流动路径结构是可能的。

    Cannula for use in drug delivery systems and systems including same
    7.
    发明授权
    Cannula for use in drug delivery systems and systems including same 失效
    用于药物输送系统和包括其的系统的插管

    公开(公告)号:US5226900A

    公开(公告)日:1993-07-13

    申请号:US924262

    申请日:1992-08-03

    CPC分类号: A61M5/1409 Y10S604/905

    摘要: The present invention provides an improved cannula that can be used to reconstitute powdered drugs in a drug delivery system. Furthermore, the present invention provides a cannula and drug delivery system incorporating same. To this end, the present invention provides a cannula structure for use in a reconstitution device for reconstituting a powdered drug comprising a cannula having a first end and a second end, and defining a channel in an interior thereof between the first and second ends. The first end is closed and includes a member for piercing a septum. The cannula includes at least two slots providing fluid communication between the channel and an exterior of the cannula. The slots are located in juxtaposition to the first end and have a width, as measured along a length of the cannula, that is less than a length, as measured around the cannula. The slots also have a minimum projected area equal to or greater than the cross-sectional area of the channel.

    摘要翻译: 本发明提供了可用于在药物递送系统中重建粉末药物的改进的套管。 此外,本发明提供了一种并入其的套管和药物输送系统。 为此,本发明提供一种用于重建装置的插管结构,用于重构包含具有第一端和第二端的套管的粉末药物,并且在其内部在第一和第二端之间限定通道。 第一端是封闭的并且包括用于刺穿隔膜的构件。 套管包括至少两个槽,其在通道和套管的外部之间提供流体连通。 狭槽位于与第一端并列的位置,并沿着插管的长度测量的宽度小于在套管周围测量的长度。 槽也具有等于或大于通道的横截面面积的最小投影面积。

    Nebulized aerosols containing nanoparticle dispersions
    10.
    发明授权
    Nebulized aerosols containing nanoparticle dispersions 失效
    含有纳米颗粒分散体的雾化气溶胶

    公开(公告)号:US06264922B1

    公开(公告)日:2001-07-24

    申请号:US08948216

    申请日:1997-10-09

    IPC分类号: A61L904

    摘要: There is disclosed an aerosol comprising droplets of an aqueous dispersion of nanoparticles, said nanoparticles comprising insoluble therapeutic or diagnostic agent particles having a surface modifier on the surface thereof. There is also disclosed a method for making the aerosol and methods for treatment and diagnosis using the aerosol.

    摘要翻译: 公开了一种包含纳米颗粒的水分散体的液滴的气溶胶,所述纳米颗粒包含在其表面上具有表面改性剂的不溶性治疗剂或诊断剂颗粒。 还公开了一种制造气溶胶的方法以及使用该气溶胶的治疗和诊断方法。