公开(公告)号：US5590651A

公开(公告)日：1997-01-07

申请号：US373662

申请日：1995-01-17

申请人： Thomas H. Shaffer ,  Marla R. Wolfson ,  Thomas F. Miller ,  Raymond Foust, III

发明人： Thomas H. Shaffer ,  Marla R. Wolfson ,  Thomas F. Miller ,  Raymond Foust, III

IPC分类号： G01N25/18 ,  A61B5/08 ,  A61B5/083 ,  A61B5/087 ,  A61M16/00 ,  F16K17/38 ,  G01N33/00 ,  G01N33/497 ,  A61B5/097

CPC分类号： G01N33/497 ,  A61M16/0054 ,  A61M16/00 ,  A61M2202/0476 ,  G01N33/0049 ,  Y10S128/913

摘要： The amount of breathable liquid eliminated from a mammal through volatilization in the lungs and/or through skin transpiration is detected by measuring the amount of saturation of the expiratory gas by vapors or the breathable liquid. Instantaneous saturation values are employed to gauge the amount of interaction in the lungs between the breathable liquid and respiratory gas flowing therein and to control selected feedback operations to maintain the maximum possible amount of interaction therebetween. The saturation level of expiratory gas is also employed to optimize operating parameters or a system for recovering the breathable liquid from the expiratory gas, directly from the patient, or from a gas or liquid ventilator. The saturation level or expiratory gas is also employed to perform functional residual capacity studies and to correct for errors in conventional functional residual capacity measurements performed while a patient undergoes partial liquid ventilation. When breathable liquid is employed as a blood substitute, the quantification or the loss of the breathable liquid from volatilization and transpiration helps to determine when to replenish the breathable liquid in the bloodstream. Vapors of one form of breathable liquid, perfluorocarbon, are employed to determine the functional residual capacity of a mammal's lung.

摘要翻译： 通过用蒸气或透气液体测量呼气气体的饱和度来检测从哺乳动物通过肺中挥发和/或通过皮肤蒸腾而消除的透气液体的量。 使用瞬时饱和值来测量在其中流动的透气液体和呼吸气体之间的肺中的相互作用的量，并且控制所选择的反馈操作以保持其间的最大可能的相互作用量。 呼吸气体的饱和水平也用于优化操作参数或用于从呼气气体直接从患者或从气体或液体通气机回收呼吸气体的系统。 还使用饱和水平或呼气气体进行功能性残留能力研究并纠正在患者进行部分液体通气时执行的常规功能残余容量测量中的误差。 当采用透气液体作为血液替代品时，透泡液体的挥发和蒸腾的定量或损失有助于确定何时补充血液中的透气液体。 使用一种透气性液体全氟化碳的蒸气来确定哺乳动物肺的功能残留能力。