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    Method for testing of embryotoxicity on chicken embryo
    1.
    发明授权
    Method for testing of embryotoxicity on chicken embryo 失效
    鸡胚胎胚胎毒性检测方法

    公开(公告)号：US4153676A

    公开(公告)日：1979-05-08

    申请号：US778043

    申请日：1977-03-16

    申请人： Richard Jelinek ,  Zdenek Rychter ,  Miroslav Peterka

    发明人： Richard Jelinek ,  Zdenek Rychter ,  Miroslav Peterka

    IPC分类号： G01N33/50 ,  A61K29/00 ,  G01N33/00 ,  G01N33/08

    CPC分类号： G01N33/5014

    摘要： Method for testing of the embryotoxicity in the chicken embryo consists in reading the response of caudal morphogenetic system (CMS) of a chicken embryo to the presence of the tested substance in subgerminal fluid. The function of the caudal morphogenetic system is evaluated 24 hours after application by a simple quantitative parameter -- the length of a newly-formed part of the trunk. The substance, which interferes with some of the basic morphogenetic processes, slows down, stops or modifies the formation of the shape of the caudal part of trunk. Considering that the quantitative parameter is used as the index of the CMS function, each member of the experimental set presents information, not only the dead and malformed embryos as in classical methods. The second part of the test, i.e. the more precise determination of the beginning of the direct embryotoxicity range, serves above all for disclosure of the effect of the tested substance on the circulation system of the embryo and smooth muscles of faetal membranes. The testing according to this method may be used in pharmaceutical productions and plants, further in chemical productions and for environmental monitoring.

    摘要翻译： 用于测试鸡胚中的胚胎毒性的方法在于读取鸡胚尾尾形态发生系统（CMS）对次生液中测试物质存在的反应。 尾部形态发生系统的功能在施用后24小时通过简单的定量参数（树干的新形成部分的长度）进行评估。 干扰一些基本形态发生过程的物质减缓，停止或改变躯干尾部形状的形成。 考虑到定量参数用作CMS功能的指标，实验组的每个成员不仅传统的方式提供了死亡和畸形胚胎的信息。 测试的第二部分，即更直接确定直接胚胎毒性范围的开始，首先是为了揭示被测物质对胚胎的循环系统和胎膜的平滑肌的影响。 根据该方法的测试可用于药物生产和植物中，进一步用于化学制品和环境监测。

    Test circuit for indication of deviation of source voltages from their set points
    2.
    发明授权
    Test circuit for indication of deviation of source voltages from their set points 失效
    用于指示源极电压与其设定点偏差的测试电路

    公开(公告)号：US4139788A

    公开(公告)日：1979-02-13

    申请号：US809431

    申请日：1977-06-23

    申请人： Josef Cibulka ,  Jaroslav Hlousek ,  Richard Jelinek ,  Jan Krtek ,  Jiri Winkler

    发明人： Josef Cibulka ,  Jaroslav Hlousek ,  Richard Jelinek ,  Jan Krtek ,  Jiri Winkler

    IPC分类号： G01R19/15 ,  H02H7/12 ,  H03K5/18

    CPC分类号： H02H7/12 ,  G01R19/15

    摘要： A test circuit for determining when one of a number of source voltages deviates from its set point. Each source voltage has coordinated comparison circuit which compares the voltage with a preset value, and which has a limited range of output voltage. Each comparison circuit has its output connected to a switching circuit. The output of each switching circuit is connected to a short circuit coil of one coupling transformer. The coupling transformer is fed from an auxiliary current source through an auxiliary coil and has as output a pick-up coil connected to an evaluation device.

    摘要翻译： 一种测试电路，用于确定多个源极电压何时偏离其设定点。 每个源电压具有协调的比较电路，其将电压与预设值进行比较，并且具有有限的输出电压范围。 每个比较电路的输出连接到开关电路。 每个开关电路的输出端连接到一个耦合变压器的短路线圈。 耦合变压器从辅助电流源通过辅助线圈馈送，并具有连接到评估装置的拾取线圈的输出。