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公开(公告)号：US6107057A
公开(公告)日：2000-08-22
申请号：US29267
申请日：1998-02-24
CPC分类号： C07K14/39 , C07K14/65 , C12N15/815 , C07K2319/00
摘要： Polynucleotides, vectors, and host cells comprising a polynucleotide having a fragment of a leader sequence and a second nucleotide sequence that encodes a polypeptide heterologous to the leader sequence, wherein the leader sequence fragment is sufficient for secretion and comprises an amino acid sequence that comprises at least about 70% sequence identity to the leader sequence of Pichia acaciae killer toxin, wherein the heterologous polypeptide is not naturally contiguous to the leader sequence, and wherein upon expression of the polynucleotide molecule in a host cell suitable for expression thereof, the heterologous polypeptide is produced that is free of additional N-terminal amino acids.
摘要翻译： PCT No.PCT / US96 / 15329 Sec。 371日期：1998年2月24日 102（e）1998年2月24日PCT PCT 1996年9月25日PCT公布。 公开号WO97 / 12044 日期1997年4月3日包含具有前导序列片段的多核苷酸和编码与前导序列异源的多肽的第二核苷酸序列的多核苷酸，载体和宿主细胞，其中前导序列片段足以分泌，并且包含氨基 其包含与毕赤酵母属杀线毒素的前导序列至少约70％序列同一性的酸序列，其中所述异源多肽不天然邻接于所述前导序列，并且其中当所述多核苷酸分子在适于表达其的宿主细胞中时 产生不含另外的N-末端氨基酸的异源多肽。
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公开(公告)号：US5556229A
公开(公告)日：1996-09-17
申请号：US368649
申请日：1995-01-04
申请人： Robert J. Bishop , Justin D. Bishop
发明人： Robert J. Bishop , Justin D. Bishop
IPC分类号： E02B3/04
CPC分类号： E02B3/04
摘要： A dynamic shoreline erosion control system includes a plurality of large rotatable hollow spheres spaced along a line at a distance from the shoreline. The spheres are held together by a heavy duty strong flexible netting which permits movement of the spheres with the incoming and outgoing waves. Openings in the spheres permit the sea water to pass through. A plurality of smaller air-filled balls are disposed within the spheres to likewise rotate under the influence of water flow and provide buoyancy. A group of spheres within a common netting is tied to a pair of pilings at the ends of the netting to limit the extent of movement. Narrower sections of the netting between spheres provide a link and spacing for adjacent elements. Like groups of spheres in nettings can be disposed in parallel pairs with staggered spacing and an array of spaced groups in various geometric arrangements can extend along a large shore area. The combined effects of the netting, spheres and balls serve to dissipate wave energy to reduce shore erosion and can trap sand that would normally be washed away to permit restoration of shore areas.
摘要翻译： 动态海岸线侵蚀控制系统包括沿着与海岸线一段距离的线间隔开的多个大的可旋转中空球体。 球体由重型强力的柔性网架组合在一起，允许球体与进出波段的移动。 球体中的开口允许海水通过。 多个较小的充气球设置在球体内同样在水流的影响下旋转并提供浮力。 一个共同的网络中的一组球体与网络末端的一对桩桩相连，以限制运动的程度。 球体之间网格的较窄部分为相邻元素提供了链接和间距。 类似于网状球体的组可以以交错的间隔平行对地布置，并且以各种几何布置的间隔开的阵列阵列可以沿着大的岸边区域延伸。 网，球和球的综合效应用于消除波浪能量以减少岸边侵蚀，并且可以捕获通常被冲走的沙子，以允许修复岸边区域。
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公开(公告)号：US5472229A
公开(公告)日：1995-12-05
申请号：US184364
申请日：1994-01-21
申请人： Robert J. Bishop , Richard L. Frantom , Robert M. Kremer , Klaus F. Ocker , Roy G. Brown , Teresa L. Bazel , Donald W. Renfoe
发明人： Robert J. Bishop , Richard L. Frantom , Robert M. Kremer , Klaus F. Ocker , Roy G. Brown , Teresa L. Bazel , Donald W. Renfoe
IPC分类号： F42B3/10 , B60R21/26 , B60R21/261 , F42B39/20
CPC分类号： B60R21/261 , B60R21/26 , F42B39/20
摘要： An air bag module (50) comprising an inflator (40) for generating inflation gas; an air bag (12) disposed about the inflator to receive the inflation gas exiting the inflator; a structure (52) for supporting at least the inflator. The inflator comprises: a pressure vessel (42) and a plurality of exit ports (16). The exit ports are arranged to render the inflator in a thrust neutral condition when the inflator is not attached to the structure. A plug (60) or plugs is provided for closing a designated set of exit ports to render the inflator in a non-thrust neutral condition when supported by the structure. Each plug is received in each of the designated exit ports and is preferably received though a portion of the structure such that if the inflator is removed from the structure each plug must also be removed, thereby opening all of previously closed exit ports and rendering the inflator in its thrust neutral condition once again.
摘要翻译： 一种气囊模块（50），包括用于产生充气气体的充气机（40） 设置在充气器周围的气囊（12），以接收离开充气器的充气气体; 用于至少支撑充气机的结构（52）。 充气机包括：压力容器（42）和多个出口（16）。 排气口布置成当充气机未附接到结构时使充气机处于推力中性状态。 提供插头（60）或塞子用于关闭指定的一组出口端口，以在由结构支撑时使充气机处于非推力中性状态。 每个塞子被接收在每个指定的出口端口中，并且优选地通过结构的一部分被接收，使得如果从结构中移除充气机，则每个塞子也必须被去除，从而打开所有先前封闭的出口并使得充气机 在其推力中性条件下再次。
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公开(公告)号：US5437188A
公开(公告)日：1995-08-01
申请号：US189228
申请日：1994-01-31
申请人： Richard Frantom , Robert J. Bishop , Robert Kremer , Klaus F. Ocker , Stephen P. McGarry , Will E. Rogers
发明人： Richard Frantom , Robert J. Bishop , Robert Kremer , Klaus F. Ocker , Stephen P. McGarry , Will E. Rogers
CPC分类号： B60R21/272 , F16F9/3264 , G01L9/12 , G01M3/3272
摘要： A post activation device to indicate that pressure the existed within a pressure vessel just prior to the opening of the pressure vessel and the resulting loss of pressurization, having a diaphragm, plug or piston (62, 130, 160, 330) capable of rupturing, moving or deforming in response to a pressure differential thereacross above one or more low limit values and for providing an indication of the pressure within the pressure vessel just prior to its being opened, and a support member (70), within the pressure vessel for supporting the diaphragm, plug or piston means.
摘要翻译： 一种后激活装置，用于指示恰好在压力容器打开之前存在于压力容器内的压力以及所导致的加压损失，具有能够破裂的隔膜，塞子或活塞（62,130,160,330） 响应于超过一个或多个下限值的压力差而移动或变形，并且用于在压力容器刚刚打开之前提供压力容器内的压力指示;以及在用于支撑的压力容器内的支撑构件（70） 隔膜，塞子或活塞装置。
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公开(公告)号：US4964654A
公开(公告)日：1990-10-23
申请号：US350431
申请日：1989-05-11
IPC分类号： B60R21/20 , B60R21/217
CPC分类号： B60R21/2171
摘要： An assembly comprising: a hollow cylindrical member or can including an opening into which a gas generator may be inserted, the gas generator of the type responsive to a control signal, for generating gas to inflate an air bag. The assembly including the air bag, for protecting, when activated, an occupant of a vehicle, comprising an inflatable bag or sack, disposed in a compacted or stored condition, during periods prior to deployment, proximate a side of the cylindrical member containing at least one aperture, the inflatable bag, including an open end disposed about the cylindrical member to receive the gas an including relatively opposing flaps extending from proximate the open end and adapted to envelop the cylindrical member, the flaps, proximate a side of the cylindrical member, away from the at least one apature, disposed in an overlapping, condition, one to the other. A band of tearable material is provided to secure the air bag in its stored or predeployment condition.
摘要翻译： 一种组件，包括：中空圆柱形构件或罐，其包括可以插入气体发生器的开口，响应于控制信号的类型的气体发生器，用于产生气体以使气囊膨胀。 包括气囊的组件，用于当被启动时保护车辆的乘客，其包括设置在压实或储存状态下的充气袋或袋，在展开之前的期间，靠近所述圆柱形构件的至少包含至少 一个孔，可充气袋，包括围绕圆柱形构件设置的开口端，用于容纳气体，包括从靠近开口端延伸的相对相对的翼片，并且适于包围圆柱形构件，靠近圆柱形构件的侧面的翼片， 远离至少一个形状，以重叠的状态彼此重叠设置。 提供可撕裂材料带以将气囊固定在其储存或预部署状态。
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公开(公告)号：US4944527A
公开(公告)日：1990-07-31
申请号：US401216
申请日：1989-08-31
IPC分类号： B60R21/201 , B60R21/217 , B60R21/261
CPC分类号： B60R21/2171 , B60R21/201 , B60R21/261
摘要： A device (20) comprising a planar metal sheet (21;21') having formed thereon at least a first set of opposing shaped slots (60a,b) such that upon forming the planar sheet as an open ended (122) generally cylindrical member or cylinder (28) first portions of the sheet, defined by the slots, extend away from the surface of the formed cylindrical member and form in conjunction with other surfaces of the sheet a plurality of first apertures (62a,b), and the extending first portions serving to define a heat sheet for shielding a portion of an air bag (100), adapted to be secured thereabout, from hot gas generated by a gas generator (50), the device including securement means, interacting with a rearward portion of the cylinderical member and adapted for urging a gas generator (50) into forward facing portions of the cylindrical member, for securing same in place.
摘要翻译： 一种装置（20），包括在其上形成有至少第一组相对的成形槽（60a，b）的平面金属片（21; 21'），使得在形成作为开口（122）的大致圆柱形构件 或圆筒（28）由狭槽限定的片材的第一部分远离所形成的圆柱形构件的表面延伸并与片材的其他表面结合形成多个第一孔（62a，b），并且延伸 第一部分用于限定用于屏蔽适于固定在其周围的气体（100）的一部分的热片以及由气体发生器（50）产生的热气体，所述装置包括固定装置，其与后部的 所述圆筒构件适于将气体发生器（50）推向所述圆柱形构件的向前的部分，以将其固定在适当位置。
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公开(公告)号：US4750840A
公开(公告)日：1988-06-14
申请号：US44354
申请日：1987-04-30
申请人： Robert J. Bishop
发明人： Robert J. Bishop
CPC分类号： B28C5/1818 , B28C5/44
摘要： A manually operated portable mixing device is provided in which a frame of knockdown construction provides means for rotatably supporting a mixing drum of centrally expanded cylindrical contour in a manner to dispose the drum axis at an angle of about 20 degrees with respect to a support surface, the drum having a large circular opening at one end and being closed at the opposed end, roller means at the rear of the frame engaging an annular groove on an axially protruding bearing member at the closed end of the drum, roller means at the front of the frame engaging outer surfaces of the drum adjacent the open end thereof, a three-sided frame extension of a size to be closely spaced from the periphery of the rotatably supported open drum end, the lower rear portion of the frame detachably supporting wheels in a manner to be slightly elevated with respect to a support surface, and the drum at the centrally expanded portion thereof, having four detachably mounted and radially extended hand-grip members at 90.degree. intervals circumferially of the drum, the hand-grip members serving the multiple functions of providing means for easily rotating the drum in mixing operations, for rearwardly tilting the assemblage to move it about on said wheels, and for forwardly tilting the assemblage and rotating the drum to facilitate the discharge of mixed contents.
摘要翻译： 提供了一种手动操作的便携式混合装置，其中敲击结构的框架提供了用于以相对于支撑表面以大约20度的角度设置鼓轴线的方式可旋转地支撑中心膨胀的圆柱形轮廓的混合鼓的装置， 滚筒在一端具有大的圆形开口并且在相对的端部处封闭，在框架后部的滚子装置与滚筒的封闭端处的轴向突出的轴承构件上的环形槽接合， 所述框架与所述鼓的开口端的外表面接合，尺寸与所述可旋转支撑的开放鼓端的周边紧密间隔的三边框架延伸部，所述框架的下后部可拆卸地支撑轮子 方式相对于支撑表面略微升高，并且在其中央膨胀部分处的鼓具有四个可拆卸地安装和径向延伸的手 - 围绕鼓的90度间隔的构件，用于多个功能的手柄构件提供用于在混合操作中容易地旋转滚筒的装置，用于使组合件向后倾斜以使其围绕所述轮子移动，并且用于向前倾斜 组合并旋转鼓以便于混合内容物的排出。
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公开(公告)号：US4157841A
公开(公告)日：1979-06-12
申请号：US824589
申请日：1977-08-15
CPC分类号： B60R22/22
摘要： A safety belt connector having an elongated means composed of a metal plate is provided with a plastic cover. The cover is formed around a major portion of the exterior surface of the elongated means preventing temperature variance thereon and presenting an attractive exterior for the connector.
摘要翻译： 具有由金属板构成的细长装置的安全带连接器设置有塑料盖。 盖子围绕细长装置的外表面的主要部分形成，防止其上的温度变化并且为连接器呈现有吸引力的外观。
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公开(公告)号：US4070038A
公开(公告)日：1978-01-24
申请号：US654481
申请日：1976-02-02
CPC分类号： B60R22/22
摘要： A safety belt connector having an elongated means composed of a metal plate is provided with a plastic cover. The cover coats a major portion of the exterior surface of the elongated means preventing temperature variance thereon and presenting an attractive exterior for the connector.
摘要翻译： 具有由金属板构成的细长装置的安全带连接器设置有塑料盖。 盖子覆盖细长装置的外表面的主要部分，防止其上的温度变化并且为连接器呈现有吸引力的外观。
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公开(公告)号：US20130274557A1
公开(公告)日：2013-10-17
申请号：US13447931
申请日：2012-04-16
IPC分类号： A61B1/32
CPC分类号： A61B17/0206 , A61B5/0488 , A61B17/025 , A61B2017/00039 , A61B2017/0262 , A61M29/00
摘要： A dilator assembly includes a dilator and a retractor member that is configured to be removably attached to the dilator.
摘要翻译： 扩张器组件包括扩张器和牵开器构件，其构造成可移除地附接到扩张器。
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