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    Methods and devices for treating vulnerable plaque
    1.
    发明申请
    Methods and devices for treating vulnerable plaque 有权
    治疗易损斑块的方法和装置

    公开(公告)号：US20070123839A1

    公开(公告)日：2007-05-31

    申请号：US11290780

    申请日：2005-11-30

    申请人： Robert Rousseau ,  Kevin Weadock

    发明人： Robert Rousseau ,  Kevin Weadock

    IPC分类号： A61N1/30

    CPC分类号： A61B17/22 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/12181 ,  A61B2017/00893 ,  A61B2017/22082 ,  A61M25/1002

    摘要： This invention provides methods, devices and kits for treating coronary artery disease, particularly “soft” or vulnerable plaque. The invention is based on the local delivery of crosslinking means to crosslink the collagen covering the plaque and other proteins that may be present at the site to stabilize the plaque and prevent leakage of thrombogenic material into the lumen of the coronary artery. In certain embodiments, catheters are employed to achieve local delivery of a crosslinking agent or ultraviolet light.

    摘要翻译： 本发明提供用于治疗冠状动脉疾病，特别是“软”或易损斑块的方法，装置和试剂盒。 本发明基于交联手段的局部递送，以交联覆盖斑块的胶原和可能存在于该部位的其它蛋白质以稳定斑块并防止血栓形成物质渗入冠状动脉的内腔。 在某些实施方案中，导管用于实现交联剂或紫外线的局部递送。

    Predictive diagnostic system in a programmable automaton
    2.
    发明授权
    Predictive diagnostic system in a programmable automaton 失效
    可编程自动机中的预测诊断系统

    公开(公告)号：US06937962B2

    公开(公告)日：2005-08-30

    申请号：US10477569

    申请日：2002-05-07

    申请人： Robert Rousseau ,  François Bonnard ,  Alain Lafuite

    发明人： Robert Rousseau ,  François Bonnard ,  Alain Lafuite

    IPC分类号： G05B19/05 ,  G06F11/30 ,  G21C17/00

    CPC分类号： G05B19/058 ,  G05B2219/13185 ,  G05B2219/14058 ,  G05B2219/14074

    摘要： The invention relates to a diagnostic system which involves the use of a piece of observed information (5) coming from a process (1) monitored by a programmable automaton (10). The diagnostic system includes: an observation module (30) which collects, at input, the information observed (5) and delivers, at output, a piece of processed information (35) to a learning module (40); and a detection module (20) which collects, at input, the observed information (5) in order to apply a detection process (21) thereto including a diagnostic function (45), which comes from the learning module (40), in order to deliver a diagnostic result (25) at output. The observation module (30) and the detection module (20) are executed by the processing unit (11) of the programmable automaton (10) in the form of function units in accordance with standard IEC1131-3. The learning module (40) elaborates the diagnostic function (45) using an algorithm based on neural networks or on fuzzy logic.

    摘要翻译： 本发明涉及一种诊断系统，其涉及使用来自由可编程自动机（10）监控的过程（1）的一条观察信息（5）。 所述诊断系统包括：观察模块（30），其在输入时收集所观察的信息（5），并且在输出时将一段经处理的信息（35）传送到学习模块（40）; 以及检测模块（20），其在输入时收集所述观察信息（5），以便依次应用来自所述学习模块（40）的诊断功能（45）应用于其上的检测处理（21） 在产出时提供诊断结果（25）。 观察模块（30）和检测模块（20）由可编程自动机（10）的处理单元（11）按照IEC1131-3标准以功能单元的形式执行。 学习模块（40）使用基于神经网络的算法或模糊逻辑来阐述诊断功能（45）。

    Surgical wound closure device
    3.
    发明申请
    Surgical wound closure device 审中-公开

    公开(公告)号：US20050034731A1

    公开(公告)日：2005-02-17

    申请号：US10640175

    申请日：2003-08-13

    申请人： Robert Rousseau ,  An-Min Sung

    发明人： Robert Rousseau ,  An-Min Sung

    IPC分类号： A61B17/08 ,  A61F13/00 ,  A61F13/02

    CPC分类号： A61B46/40 ,  A61B17/085 ,  A61F13/02 ,  A61F13/023 ,  A61F2013/0057

    摘要： One embodiment includes a surgical wound closure device comprising a substrate having a proximal surface and a distal surface; a drape having a proximal surface and a distal surface, and being disposed proximally to said substrate; and an adhesive layer having a proximal surface and a distal surface; said drape being disposed releasably adherently to said distal surface of said adhesive layer. Another embodiment includes a surgical procedure comprising the steps of providing a surgical wound closure device comprising a substrate having a proximal surface and a distal surface, a drape having a proximal surface and a distal surface and being disposed proximally to said substrate, and an adhesive layer having a proximal surface and a distal surface, where said drape being disposed releasably adherently to said distal surface of said adhesive layer; positioning the proximal surface of said adhesive layer on the skin of a patient; separating said substrate from said drape and adhesive layer to expose said distal surface of said drape; making a surgical incision through said drape; performing a surgical procedure; removing said drape from said adhesive layer to expose said distal surface of said adhesive layer; aligning said substrate and said adhesive layer; and adhering said proximal surface of said substrate to said distal surface of said adhesive layer.

    Lumber unscrambler and conveyor
    5.
    发明授权
    Lumber unscrambler and conveyor 失效
    木材解扰器和输送机

    公开(公告)号：US07131527B2

    公开(公告)日：2006-11-07

    申请号：US10677410

    申请日：2003-10-02

    申请人： Pascal Andre Joseph Robitaille ,  Martin Robert Rousseau ,  Laurent Joseph Yvon Trudel

    发明人： Pascal Andre Joseph Robitaille ,  Martin Robert Rousseau ,  Laurent Joseph Yvon Trudel

    IPC分类号： B65G25/00

    CPC分类号： B65G25/08 ,  B27M3/002

    摘要： A lumber unscrambler and conveyor having first and second rigid units mounted at an incline on a support structure. Each unit has a plurality of spaced apart parallel plates in series along the incline and parallel thereto. The plates on the respective first and second units are interleaved in alternate relation. The plates have an upper article supporting surface and a leading edge generally transverse to the incline. The leading edge of plates proximate the in-feed end are of greater depth than those further along the path toward the out-feed end. The units are supported on the support structure to move relative thereto and one another. The units are driven in synchronized out of phase relation reciprocating along the inclined path. A hopper at the in-feed end receives and holds a supply of lumber pieces of selected dimension and as the plates reciprocate they move pieces of the lumber from the hopper to the out-feed end discharging normally only a single stick one after another.

    摘要翻译： 木材解扰器和输送机，其具有安装在支撑结构上的倾斜处的第一和第二刚性单元。 每个单元具有沿着倾斜并与其平行的多个间隔开的平行板。 相应的第一和第二单元上的板互换交替。 板具有上部物品支撑表面和大致横向于倾斜的前缘。 靠近进给端的板的前缘比沿进给端的路径的前缘更深。 这些单元被支撑在支撑结构上以相对于其彼此移动。 这些单元以沿着倾斜路径往复运动的同步相位关系驱动。 进料端的料斗接收并保持选定尺寸的木材供应，并且当板往复运动时，它们将木材的碎片从料斗移动到出料端，一般一个接一个地排放一个单一的棒。

    Surgical wound closure device
    6.
    发明申请
    Surgical wound closure device 有权
    手术伤口闭合装置

    公开(公告)号：US20050034732A1

    公开(公告)日：2005-02-17

    申请号：US10830948

    申请日：2004-04-23

    申请人： Robert Rousseau ,  An-Min Sung

    发明人： Robert Rousseau ,  An-Min Sung

    IPC分类号： A61B17/08 ,  A61B19/08 ,  A61F13/00 ,  A61F13/02 ,  A61B19/00 ,  A61F5/37

    CPC分类号： A61F13/023 ,  A61B17/085 ,  A61F13/0206 ,  A61F13/0209 ,  A61F13/022 ,  A61F13/0223 ,  A61F13/0259 ,  A61F2013/0057

    摘要： One embodiment includes a surgical wound closure device comprising a substrate having a proximal surface and a distal surface; a drape having a proximal surface and a distal surface, and being disposed proximally to said substrate; and an adhesive layer having a proximal surface and a distal surface; said drape being disposed releasably adherently to said distal surface of said adhesive layer. Another embodiment includes a surgical procedure comprising the steps of providing a surgical wound closure device comprising a substrate having a proximal surface and a distal surface, a drape having a proximal surface and a distal surface and being disposed proximally to said substrate, and an adhesive layer having a proximal surface and a distal surface, where said drape being disposed releasably adherently to said distal surface of said adhesive layer; positioning the proximal surface of said adhesive layer on the skin of a patient; separating said substrate from said drape and adhesive layer to expose said distal surface of said drape; making a surgical incision through said drape; performing a surgical procedure; removing said drape from said adhesive layer to expose said distal surface of said adhesive layer; aligning said substrate and said adhesive layer; and adhering said proximal surface of said substrate to said distal surface of said adhesive layer.

    摘要翻译： 一个实施例包括外科伤口闭合装置，其包括具有近端表面和远侧表面的基底; 具有近侧表面和远侧表面的盖布，并且被布置在所述基底的近侧; 以及具有近端表面和远侧表面的粘合剂层; 所述盖布可剥离地贴合在所述粘合剂层的所述远端表面上。 另一个实施方案包括一种外科手术方法，其包括提供包括具有近端表面和远侧表面的基底的外科伤口闭合装置，具有近端表面和远端表面的盖布，并且邻近所述基底设置的粘合剂层 具有近端表面和远侧表面，其中所述盖布可剥离地设置在所述粘合剂层的所述远侧表面上; 将所述粘合剂层的近侧表面定位在患者的皮肤上; 将所述基底与所述覆盖层和粘合剂层分离以暴露所述盖布的所述远侧表面; 通过悬垂手术切口; 执行外科手术; 从所述粘合剂层去除所述盖布，以暴露所述粘合剂层的所述远侧表面; 对准所述基底和所述粘合剂层; 以及将所述基底的所述近端表面粘附到所述粘合剂层的所述远侧表面。

    Method of separating components in a biological fluid
    7.
    发明授权
    Method of separating components in a biological fluid 失效
    在生物流体中分离组分的方法

    公开(公告)号：US4158547A

    公开(公告)日：1979-06-19

    申请号：US695311

    申请日：1976-06-11

    申请人： Robert Rousseau ,  Charles A. Manganaro

    发明人： Robert Rousseau ,  Charles A. Manganaro

    IPC分类号： G01N33/50 ,  G01N33/78 ,  G01N33/16

    CPC分类号： G01N33/50 ,  G01N33/78 ,  Y10S436/804 ,  Y10S436/825 ,  Y10S436/826

    摘要： Insolubilized serum protein adsorbent, for example bovine serum albumin, of small particle size is an excellent adsorbent for adsorbable components in a biological fluid such as serum. Macroaggregated and polymerized albumin are particularly suited as adsorbents for unbound thyroid hormone in serum and can be used in diagnostic kits for determining total T.sub.4 and for T.sub.3 uptake.

    摘要翻译： 不溶解的血清蛋白质吸附剂，例如小粒径的血清白蛋白，是生物液体如血清中可吸附组分的优良吸附剂。 大量聚集和聚合的白蛋白特别适用于血清中未结合甲状腺激素的吸附剂，可用于诊断试剂盒，用于测定总T4和T3摄取。

    Sternal closure device and method
    10.
    发明申请
    Sternal closure device and method 有权
    胸围闭合装置及方法

    公开(公告)号：US20050240189A1

    公开(公告)日：2005-10-27

    申请号：US10830122

    申请日：2004-04-22

    申请人： Robert Rousseau ,  Kevin Weadock ,  Etan Chatlynne

    发明人： Robert Rousseau ,  Kevin Weadock ,  Etan Chatlynne

    IPC分类号： A61B17/56 ,  A61B17/68 ,  A61B17/82

    CPC分类号： A61B17/683 ,  A61B17/823

    摘要： A device and method for joining a severed sternum is disclosed. The device includes first and second bearing members, a sternum joining member having an axis and first and second ends, the first end connected to the first bearing member, the second bearing member adapted to engage the sternum joining member, and the sternum joining member is adapted to traverse the exposed cancellous surfaces of the sternal portions. The method includes moving the second bearing member along the axis of the sternum joining member toward the first bearing member, with the sternum joining member traversing the cancellous surfaces of both sternal portions, and securing the second bearing member on the axis of the sternum joining member so that the severed sternum is securely closed. A kit including sternal closure devices and other tools for closing a sternotomy is also disclosed.

    摘要翻译： 公开了一种用于连接切断的胸骨的装置和方法。 该装置包括第一和第二轴承构件，具有轴线的胸骨连接构件和第一和第二端，第一端连接到第一轴承构件，第二轴承构件适于接合胸骨接合构件，并且胸骨接合构件是 适于穿过胸骨部分的暴露的松质骨表面。 所述方法包括使所述第二支承构件沿着所述胸骨接合构件的轴线朝向所述第一轴承构件移动，所述胸骨接合构件横穿所述两个胸骨部的松质面，并且将所述第二轴承构件固定在所述胸骨接合构件的轴线上 使得切断的胸骨牢固地关闭。 还公开了一种包括胸骨闭合装置和用于闭合胸骨切开术的其它工具的套件。