公开(公告)号：US20050047963A1

公开(公告)日：2005-03-03

申请号：US10865207

申请日：2004-06-10

申请人： Scott Safar ,  Stephen Herchenbach ,  Chadwick Dunn ,  Charles Galitz ,  Julius Toth ,  Ronald Kukla ,  Michael Lowery ,  Eric Shain

发明人： Scott Safar ,  Stephen Herchenbach ,  Chadwick Dunn ,  Charles Galitz ,  Julius Toth ,  Ronald Kukla ,  Michael Lowery ,  Eric Shain

IPC分类号： B01L3/00 ,  B01L3/14 ,  B67D99/00 ,  G01N1/00 ,  G01N35/00 ,  G01N35/10

CPC分类号： G01N35/1004 ,  B01L3/50255 ,  B01L3/5082 ,  B01L99/00 ,  B01L2200/0668 ,  B01L2400/049 ,  B01L2400/0655 ,  B01L2400/0688 ,  G01N35/0098 ,  G01N35/1065 ,  Y10T137/0391 ,  Y10T137/0396 ,  Y10T436/25375 ,  Y10T436/2575

摘要： A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.

摘要翻译： 具有底部排放开口的反应容器，其通过流体的表面张力支撑选定的未压缩流体的头部。 装置处理区域包括支撑隔离排列的反应容器，与其支撑的容器的排放开口连通的通道，以及用于选择性地通过排放开口排出流体的压力源。 通常，水平条形磁体被支撑用于在容器列之间选择的垂直运动。 分配头具有可选择性地定位在X选择的反应容器上的X个排出口。 计量泵机构选择性地测量选定量的流体的批量供应（其中X是至少四个），并且选择性地将经计量的所选量通过排放开口泵送到选定的反应容器。 还包括使用压力源从容器中抽取流体并移动磁体以形成分析物颗粒的方法。