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公开(公告)号:US20060188577A1
公开(公告)日:2006-08-24
申请号:US10553092
申请日:2004-04-16
申请人: Naoki Kimura , Ryuichi Oda , Gen Masuda , Toshifumi Hashiba , Kazutoshi Hayakawa
发明人: Naoki Kimura , Ryuichi Oda , Gen Masuda , Toshifumi Hashiba , Kazutoshi Hayakawa
IPC分类号: A61K9/14
CPC分类号: G01N33/544 , C12Q1/6834 , G01N33/54313
摘要: By using a biologically active substance-immobilized device, which comprises a base particle comprising a core particle and an organic compound having two or more hydrophilic groups and immobilized on the core particle by a chemical bond and a biologically active substance bonded to the base particle via the organic compound, a substance specifically bonding to the biologically active substance is detected or measured.
摘要翻译: 通过使用生物活性物质固定化装置,其包括含有核心颗粒和具有两个或更多个亲水基团的有机化合物的基础颗粒,并通过化学键固定在芯颗粒上,并且通过粘合到基础颗粒的生物活性物质经由 检测或测量有机化合物,特异性结合生物活性物质的物质。
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公开(公告)号:US20060051750A1
公开(公告)日:2006-03-09
申请号:US10501691
申请日:2003-01-31
申请人: Ryuichi Oda , Naoki Kimura
发明人: Ryuichi Oda , Naoki Kimura
CPC分类号: C07H21/00 , C07B2200/11 , C40B40/00
摘要: A nucleic acid is immobilized on a carrier by spotting a solution of the nucleic acid on the carrier comprising a synthetic resin such as polycarbonate, polymethyl methacrylate, acrylonitrile/butadiene/styrene copolymer, polyethylene, polyethylene terephthalate, polyphenol, polystyrene, polyacrylonitrile, polyvinyl chloride, or aramide, drying the solution, and irradiating the carrier with an ultraviolet ray containing a component having a wavelength of 280 nm, preferably for 100 mJ/cm2 or more.
摘要翻译: 将核酸固定在载体上,包含合成树脂如聚碳酸酯,聚甲基丙烯酸甲酯,丙烯腈/丁二烯/苯乙烯共聚物,聚乙烯,聚对苯二甲酸乙二醇酯,多酚,聚苯乙烯,聚丙烯腈,聚氯乙烯 或芳族聚酰胺,干燥溶液,并用含有波长280nm的成分的紫外线照射载体,优选为100mJ / cm 2以上。
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公开(公告)号:US20060068392A1
公开(公告)日:2006-03-30
申请号:US10535582
申请日:2003-11-25
申请人: Naoki Kimura , Ryuichi Oda
发明人: Naoki Kimura , Ryuichi Oda
CPC分类号: G01N33/553 , B01J19/0046 , B01J2219/00315 , B01J2219/00364 , B01J2219/00387 , B01J2219/005 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B82Y30/00 , C12Q1/6834
摘要: A solution of a nucleic acid is spotted on a metal carrier consisting of a metal selected from Groups I, II, III, IV, V, VI, and VII of second to seventh periods and transition elements in a periodic table, or of an alloy containing the metal, and the solution is dried. Then, the nucleic acid is immobilized on the carrier spotted with the solution by irradiating the carrier with an ultraviolet ray containing a component having a wavelength of 280 nm, of which irradiation dose is 100 mJ/cm2 or more.
摘要翻译: 将核酸溶液点在由选自第二至第七个周期的第I,II,III,IV,V,VI和VII族的金属组成的金属载体上,周期表中的过渡元素,或合金 含有金属,溶液干燥。 然后,通过用包含波长280nm的成分的紫外线照射载体,照射剂量为100mJ / cm 2以上,将核酸固定在载体上, 更多。
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