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8 条记录 (耗时 0.011 秒)

    Pharmaceutical composition for inhalation
    1.
    发明授权
    Pharmaceutical composition for inhalation 有权
    用于吸入的药物组合物

    公开(公告)号：US09517204B2

    公开(公告)日：2016-12-13

    申请号：US14344467

    申请日：2012-09-13

    申请人： Satomi Onoue ,  Shizuo Yamada

    发明人： Satomi Onoue ,  Shizuo Yamada

    IPC分类号： A61K9/14 ,  A61K47/26 ,  A61K31/4418 ,  A61K9/00 ,  A61M15/00 ,  A61M11/00

    CPC分类号： A61K9/14 ,  A61K9/0075 ,  A61K9/145 ,  A61K9/146 ,  A61K31/4418 ,  A61K47/26 ,  A61M11/002 ,  A61M15/00 ,  A61M2202/064

    摘要： The present invention relates to a powder formulation which reduces side effect risk of a medicine having a side effect of drug-induced photodermatosis and increases therapeutic effect, and relates to the method for producing the same.Said powder formulation makes inhalation therapy possible by carrying out aerosolization easily, and since pharmacological effect in lung local part is increased, it is possible to decrease the dose. Skin transmigration of said medicine is controlled by a lung specific delivery technology, and photodermatosis which is a side effect can be controlled.

    摘要翻译： 所述粉末制剂可以容易地进行雾化，可以进行吸入治疗，并且由于肺局部部位的药理作用增加，因此可以降低剂量。 所述药物的皮肤转移由肺特异性递送技术控制，并且可以控制作为副作用的光皮质病变。

    Separation and recovery of 1,4-diazabicyclo-(2,2,2)-octane
    2.
    发明授权
    Separation and recovery of 1,4-diazabicyclo-(2,2,2)-octane 失效
    1,4-二氮杂双环 - （2,2,2） - 辛烷的分离和回收

    公开(公告)号：US4216323A

    公开(公告)日：1980-08-05

    申请号：US958398

    申请日：1978-11-07

    申请人： Susumi Otsuki ,  Shizuo Yamada ,  Yaichro Ono

    发明人： Susumi Otsuki ,  Shizuo Yamada ,  Yaichro Ono

    IPC分类号： B01D3/36 ,  C07D487/08 ,  C07D487/18

    CPC分类号： C07D487/08

    摘要： 1,4-Diazabicyclo-(2,2,2)-octane is separated and recovered by adding water to a crude 1,4-diazabicyclo-(2,2,2)-octane including an alkyl pyrazine and other amines and then, separating 1,4-diazabicyclo-(2,2,2)-octane by a distillation of water and the alkyl pyrazine and a crystallization.

    摘要翻译： 通过向包括烷基吡嗪和其它胺的粗1,4-二氮杂双环 - （2,2,2） - 辛烷的水中加入水分离并回收1,4-二氮杂双环 - （2,2,2） - 辛烷， 通过蒸馏水和烷基吡嗪并结晶分离1,4-二氮杂双环 - （2,2,2） - 辛烷。

    Process for producing 2-nitrocycloalkanones
    4.
    发明授权
    Process for producing 2-nitrocycloalkanones 失效
    2-硝基环烷酮的制备方法

    公开(公告)号：US3959380A

    公开(公告)日：1976-05-25

    申请号：US559795

    申请日：1975-03-19

    申请人： Shizuo Yamada ,  Hiroo Sasaki ,  Tetsuo Tanaka

    发明人： Shizuo Yamada ,  Hiroo Sasaki ,  Tetsuo Tanaka

    IPC分类号： C07C45/04

    摘要： 2-Nitrocycloalkanone, and its derivatives are prepared by reacting in a single step a cycloalkene with nitrogen dioxide and an oxygen containing gas in the presence of an aromatic hydrocarbon solvent having 6 - 10 carbon atoms, and a dimethylsulfoxide catalyst.

    摘要翻译： 2-硝基环烷酮及其衍生物通过在具有6-10个碳原子的芳族烃溶剂和二甲基亚砜催化剂的存在下，在一个步骤中使环烯烃与二氧化氮和含氧气体反应来制备。

    Film image registration system with image filing and illumination control
    5.
    发明授权
    Film image registration system with image filing and illumination control 失效
    具有图像归档和照明控制的胶片图像配准系统

    公开(公告)号：US5243196A

    公开(公告)日：1993-09-07

    申请号：US873213

    申请日：1992-04-24

    申请人： Shizuo Yamada

    发明人： Shizuo Yamada

    IPC分类号： H04N1/21 ,  H04N1/40

    CPC分类号： H04N1/40056 ,  H04N1/2166

    摘要： A film image registration system includes a film reader for optically reading a front surface of a film set therein to obtain a film image. A film illumination device emits light to illuminate the film from a back surface of the film. The quantity of light emitted by the film illumination device is controlled according to a given command. The film image is received and formed into an image data file which is stored in a mass data storage.

    摘要翻译： 胶片图像配准系统包括：胶片读取器，用于光学读取其中设置的胶片的前表面以获得胶片图像。 胶片照明装置发射光以从胶片的背面照射胶片。 根据给定的命令控制由胶片照明装置发射的光量。 电影图像被接收并形成为存储在大容量数据存储器中的图像数据文件。

    Exhaust gas recirculation system
    6.
    发明授权
    Exhaust gas recirculation system 失效
    废气再循环系统

    公开(公告)号：US4285317A

    公开(公告)日：1981-08-25

    申请号：US105119

    申请日：1979-12-19

    申请人： Yasuo Takahara ,  Shigeo Hayashi ,  Shizuo Yamada ,  Norio Shibata

    发明人： Yasuo Takahara ,  Shigeo Hayashi ,  Shizuo Yamada ,  Norio Shibata

    IPC分类号： F02M25/07 ,  F02M25/06

    CPC分类号： F02M26/58 ,  F02M26/56

    摘要： An exhaust gas recirculation system for an internal combustion engine in which an exhaust gas control valve and a pressure regulating valve is constructed as one body to facilitate the mounting of the system on the engine and to improve the response characteristic of the system. Also, the chamber of the pressure regulating valve opposite to the chamber for receiving the exhaust gas is subjected to a pressure which is controlled in corresponding to the state of engine operation such as load, engine speed or the like, so that the rate of the exhaust gas recirculation is controlled in accordance with the state of engine operation.

    摘要翻译： 一种用于内燃机的废气再循环系统，其中排气控制阀和压力调节阀被构造为一体，以便于将系统安装在发动机上并改善系统的响应特性。 此外，与用于接收废气的室相对的压力调节阀的室受到与发动机运转状态（例如负载，发动机转速等）相应的控制的压力，使得 废气再循环根据发动机运转状态进行控制。

    PHARMACEUTICAL COMPOSITION FOR INHALATION
    7.
    发明申请
    PHARMACEUTICAL COMPOSITION FOR INHALATION 有权
    用于吸入的药物组合物

    公开(公告)号：US20140341998A1

    公开(公告)日：2014-11-20

    申请号：US14344467

    申请日：2012-09-13

    申请人： Satomi Onoue ,  Shizuo Yamada

    发明人： Satomi Onoue ,  Shizuo Yamada

    IPC分类号： A61K9/14 ,  A61K47/26 ,  A61K31/4418

    CPC分类号： A61K9/14 ,  A61K9/0075 ,  A61K9/145 ,  A61K9/146 ,  A61K31/4418 ,  A61K47/26 ,  A61M11/002 ,  A61M15/00 ,  A61M2202/064

    摘要： The present invention relates to a powder formulation which reduces side effect risk of a medicine having a side effect of drug-induced photodermatosis and increases therapeutic effect, and relates to the method for producing the same.Said powder formulation makes inhalation therapy possible by carrying out aerosolization easily, and since pharmacological effect in lung local part is increased, it is possible to decrease the dose. Skin transmigration of said medicine is controlled by a lung specific delivery technology, and photodermatosis which is a side effect can be controlled.

    摘要翻译： 本发明涉及减少具有药物诱导的光皮质病的副作用的药物的副作用风险并增加治疗效果的粉末制剂，并涉及其制备方法。 所述粉末制剂可以容易地进行雾化，可以进行吸入治疗，并且由于肺局部部位的药理作用增加，因此可以降低剂量。 所述药物的皮肤转移由肺特异性递送技术控制，并且可以控制作为副作用的光皮质病变。