公开(公告)号：US20170100585A1

公开(公告)日：2017-04-13

申请号：US15382795

申请日：2016-12-19

申请人： SONOVIA HOLDINGS LLC

发明人： MICHAEL R. HALL ,  JOHN C. CASTEL ,  DAWN CASTEL

IPC分类号： A61N1/32 ,  A61N1/36 ,  A61M37/00 ,  A61N7/00 ,  A61N1/30 ,  A61N1/04 ,  A61N5/06

CPC分类号： A61N1/328 ,  A61F7/007 ,  A61F2007/0052 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61M37/0092 ,  A61N1/0432 ,  A61N1/0452 ,  A61N1/30 ,  A61N1/36014 ,  A61N5/0613 ,  A61N5/0616 ,  A61N7/00 ,  A61N2005/0653 ,  A61N2007/0034 ,  A61N2007/0073

摘要： A flexible device having a layered structure for delivering electrical stimulation and one or both of light and ultrasound to a skin surface is provided. The device is flexible so as to form a non-planar contact surface against the skin surface, and includes one or both of (a) a flexible light emitter layer positioned between two flexible conductive layers that emits light when driven by a power source and (b) a flexible ultrasound emitter layer positioned between two flexible conductive layers that produces ultrasound when driven by a power source. The device also includes a flexible electrical stimulation layer that functions as an electrode and is configured to provide electrical stimulation when driven by a power source.

公开(公告)号：US20140276248A1

公开(公告)日：2014-09-18

申请号：US14214188

申请日：2014-03-14

申请人： SONOVIA HOLDINGS LLC

发明人： Michael R. HALL ,  John C. CASTEL ,  Dawn CASTEL

IPC分类号： A61M37/00 ,  A61N1/36 ,  A61N7/00 ,  A61N5/06

CPC分类号： A61N1/328 ,  A61F7/007 ,  A61F2007/0052 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61M37/0092 ,  A61N1/0432 ,  A61N1/0452 ,  A61N1/30 ,  A61N1/36014 ,  A61N5/0613 ,  A61N5/0616 ,  A61N7/00 ,  A61N2005/0653 ,  A61N2007/0034 ,  A61N2007/0073

摘要： A system for delivering light and/or ultrasound across a skin surface is provided. The system includes a device having a layered structure comprising one or both of a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. The system also includes one or more sensors in contact with the skin surface and a controller electrically coupled to the device and the sensor. The controller is operable to receive sensor data from the sensor and dynamically control the device in response to the received sensor data.

摘要翻译： 提供了一种用于在皮肤表面上传递光和/或超声波的系统。 该系统包括具有包括光源和超声换能器中的一个或两个的分层结构的装置。 光源包括电耦合到第一导电层和第二导电层的柔性光发射极层，其中第一和第二导电层中的至少一个是透明的。 超声换能器包括电耦合到第三导电层和第四导电层的柔性超声发射体层。 该系统还包括与皮肤表面接触的一个或多个传感器和电耦合到该装置和传感器的控制器。 控制器可操作以从传感器接收传感器数据并且响应于所接收的传感器数据来动态地控制设备。

公开(公告)号：US20140276247A1

公开(公告)日：2014-09-18

申请号：US14213999

申请日：2014-03-14

申请人： SONOVIA HOLDINGS LLC

发明人： MICHAEL R. HALL ,  John C. Castel ,  Dawn Castel

IPC分类号： A61N5/06 ,  A61N1/32 ,  A61N7/00

CPC分类号： A61N1/328 ,  A61F7/007 ,  A61F2007/0052 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61M37/0092 ,  A61N1/0432 ,  A61N1/0452 ,  A61N1/30 ,  A61N1/36014 ,  A61N5/0613 ,  A61N5/0616 ,  A61N7/00 ,  A61N2005/0653 ,  A61N2007/0034 ,  A61N2007/0073

摘要： A device for delivering light and ultrasound across a skin surface is provided. The device has a layered structure comprising a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. In one embodiment, the light source comprises an organic light emitting diode or a plurality of printed light emitting diodes and the ultrasonic transducer comprises a piezoelectric coating. The device may be provided with a therapeutic or cosmetic composition to be applied to the skin surface, wherein the light and ultrasound emitted from the device cause transdermal transport of the composition through the skin surface.

摘要翻译： 提供了一种用于在皮肤表面上递送光和超声波的装置。 该装置具有包括光源和超声换能器的分层结构。 光源包括电耦合到第一导电层和第二导电层的柔性光发射极层，其中第一和第二导电层中的至少一个是透明的。 超声换能器包括电耦合到第三导电层和第四导电层的柔性超声发射体层。 在一个实施例中，光源包括有机发光二极管或多个印刷发光二极管，超声波换能器包括压电涂层。 该装置可以设置有施用于皮肤表面的治疗或化妆品组合物，其中从该装置发射的光和超声波导致组合物透皮转运穿过皮肤表面。

公开(公告)号：US09561357B2

公开(公告)日：2017-02-07

申请号：US14213999

申请日：2014-03-14

申请人： SONOVIA HOLDINGS LLC

发明人： Michael R. Hall ,  John C. Castel ,  Dawn Castel

IPC分类号： A61N5/06 ,  A61N1/32 ,  A61N7/00 ,  A61M37/00 ,  A61N1/36 ,  A61N1/04 ,  A61F7/00 ,  A61F7/02

CPC分类号： A61N1/328 ,  A61F7/007 ,  A61F2007/0052 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61M37/0092 ,  A61N1/0432 ,  A61N1/0452 ,  A61N1/30 ,  A61N1/36014 ,  A61N5/0613 ,  A61N5/0616 ,  A61N7/00 ,  A61N2005/0653 ,  A61N2007/0034 ,  A61N2007/0073

摘要： A device for delivering light and ultrasound across a skin surface is provided. The device has a layered structure comprising a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. In one embodiment, the light source comprises an organic light emitting diode or a plurality of printed light emitting diodes and the ultrasonic transducer comprises a piezoelectric coating. The device may be provided with a therapeutic or cosmetic composition to be applied to the skin surface, wherein the light and ultrasound emitted from the device cause transdermal transport of the composition through the skin surface.

摘要翻译： 提供了一种用于在皮肤表面上递送光和超声波的装置。 该装置具有包括光源和超声换能器的分层结构。 光源包括电耦合到第一导电层和第二导电层的柔性光发射极层，其中第一和第二导电层中的至少一个是透明的。 超声换能器包括电耦合到第三导电层和第四导电层的柔性超声发射体层。 在一个实施例中，光源包括有机发光二极管或多个印刷发光二极管，超声波换能器包括压电涂层。 该装置可以设置有施用于皮肤表面的治疗或化妆品组合物，其中从该装置发射的光和超声波导致组合物透皮转运穿过皮肤表面。

公开(公告)号：US09061128B2

公开(公告)日：2015-06-23

申请号：US14214188

申请日：2014-03-14

申请人： SONOVIA HOLDINGS LLC

发明人： Michael R. Hall ,  John C. Castel ,  Dawn Castel

IPC分类号： A61M37/00 ,  A61N1/36 ,  A61N7/00 ,  A61N1/32 ,  A61N5/06 ,  A61N1/04 ,  A61F7/00 ,  A61F7/02

CPC分类号： A61N1/328 ,  A61F7/007 ,  A61F2007/0052 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61M37/0092 ,  A61N1/0432 ,  A61N1/0452 ,  A61N1/30 ,  A61N1/36014 ,  A61N5/0613 ,  A61N5/0616 ,  A61N7/00 ,  A61N2005/0653 ,  A61N2007/0034 ,  A61N2007/0073

摘要： A system for delivering light and/or ultrasound across a skin surface is provided. The system includes a device having a layered structure comprising one or both of a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. The system also includes one or more sensors in contact with the skin surface and a controller electrically coupled to the device and the sensor. The controller is operable to receive sensor data from the sensor and dynamically control the device in response to the received sensor data.

摘要翻译： 提供了一种用于在皮肤表面上传递光和/或超声波的系统。 该系统包括具有包括光源和超声换能器中的一个或两个的分层结构的装置。 光源包括电耦合到第一导电层和第二导电层的柔性光发射极层，其中第一和第二导电层中的至少一个是透明的。 超声换能器包括电耦合到第三导电层和第四导电层的柔性超声发射体层。 该系统还包括与皮肤表面接触的一个或多个传感器和电耦合到该装置和传感器的控制器。 控制器可操作以从传感器接收传感器数据并且响应于所接收的传感器数据来动态地控制设备。