公开(公告)号：US20120040898A1

公开(公告)日：2012-02-16

申请号：US13264687

申请日：2010-04-16

申请人： Teisuke Takahashi ,  Saeko Uchida

发明人： Teisuke Takahashi ,  Saeko Uchida

IPC分类号： A61K31/382 ,  A61K31/4965 ,  A61K31/4015 ,  A61K38/26 ,  A61K31/4985 ,  A61K31/445 ,  A61K31/702 ,  A61P3/10 ,  A61K38/28 ,  A61K31/4439

CPC分类号： A61K31/4439 ,  A61K31/155 ,  A61K31/382 ,  A61K31/64 ,  A61K31/7034 ,  A61K45/06 ,  A61K2300/00

摘要： A pharmaceutical composition comprising a combination of (A) a 1-thio-D-glucitol compound represented by the general formula (I) and (B) at least one member of the group consisting of biguanides, insulin secretagogues, insulin sensitizers, insulins, dipeptidyl peptidase IV inhibitors, α-glucosidase inhibitors, and GLP-1 mimetics, has superior efficacy in preventing or treating diabetes mellitus, diseases associated with diabetes mellitus, or complications of diabetes mellitus and yet it causes no appreciable side effects.

摘要翻译： 一种药物组合物，其包含（A）由通式（I）表示的1-硫代-D-葡萄糖醇化合物和（B）的组合，所述组合由双胍，胰岛素促分泌素，胰岛素敏化剂，胰岛素， 二肽基肽酶IV抑制剂，α-葡糖苷酶抑制剂和GLP-1模拟物在预防或治疗糖尿病，与糖尿病相关的疾病或糖尿病并发症方面具有优异的疗效，但没有明显的副作用。

公开(公告)号：US20060214029A1

公开(公告)日：2006-09-28

申请号：US10569006

申请日：2004-08-23

申请人： Katsumi Morikawa ,  Joki Yoshitomi ,  Keisuke Asano ,  Saeko Uchida

发明人： Katsumi Morikawa ,  Joki Yoshitomi ,  Keisuke Asano ,  Saeko Uchida

IPC分类号： B05B7/06

CPC分类号： C04B35/66 ,  B22D41/507 ,  B22D41/54 ,  B22D41/58 ,  C04B35/013 ,  C04B35/06 ,  C04B35/18 ,  C04B2235/3821 ,  C04B2235/3826 ,  C04B2235/402 ,  C04B2235/428 ,  C04B2235/77 ,  C04B2235/94 ,  C04B2235/96 ,  C04B2235/9607 ,  C04B2235/9676

摘要： Disclosed is a nozzle for continuous casting of clean steel, capable of preventing adhesion of Al2O3-based inclusions to a wall surface of the inner hole of the nozzle while fully achieving an effect of a swirl vane provided as a means to prevent occurrence of drift in molten steel passing through the inner hole. The swirl vane is disposed in the inner hole having the wall surface at least partly formed as a tubular-shaped refractory layer prepared by controlling a weight ratio of CaO/MgO and an apparent porosity to have a thickness of 3 to 20 mm, so as to prevent adhesion of Al2O3-based inclusions to the wall surface and the swirl vane while effectively maintaining the anti-drift effect for long hours. Further, inert gas is injected into a molten steel flow between an upper nozzle and the swirl vane to facilitate surfacing of Al2O3-based inclusions in a mold and reduce Al2O3-based inclusions in molten steel so as to achieve stable casting operation and high-quality steel with high cleanness.

摘要翻译： 公开了一种用于连续铸造清洁钢的喷嘴，其能够防止基于Al 2 N 3 O 3的夹杂物与喷嘴内孔的壁表面的粘合，同时完全 实现了作为防止通过内孔的钢水漂移发生的装置的旋流叶片的效果。 旋流叶片设置在具有壁表面的内孔中，至少部分地形成为通过将CaO / MgO的重量比和表观孔隙率控制为3至20mm的厚度而制备的管状耐火层，以便 以防止将Al 2 O 3 O 3 3基的夹杂物粘附到壁表面和旋流叶片上，同时有效地保持长时间的抗漂移效果。 此外，将惰性气体注入到上喷嘴和旋流叶片之间的钢水流中，以便使模具中的Al 2 N 3 O 3基夹杂物表面化并且还原Al 在钢水中含有2 3 的夹杂物，以实现稳定的铸造操作和高清洁度的优质钢。

公开(公告)号：US5844660A

公开(公告)日：1998-12-01

申请号：US911976

申请日：1997-08-15

申请人： Saeko Uchida ,  Yasuo Kato ,  Kunihiko Hara

发明人： Saeko Uchida ,  Yasuo Kato ,  Kunihiko Hara

IPC分类号： A61B3/103 ,  A61B3/107 ,  A61B3/15 ,  A61B3/10

CPC分类号： A61B3/107 ,  A61B3/103 ,  A61B3/152

摘要： An objective refraction measurement apparatus includes a separate chart having a pair of charts arranged separately, an optical system for projecting the separate chart to an eye to be examined through a focusing lens and a diaphragm having a pair of through holes arranged corresponding to the separate arrangement of the pair of charts, an operating unit for performing focusing operation to the eye, and a control unit for moving the focusing lens on the basis of the focusing operation along the optical axis direction by the operating unit to obtain the projection images of the pair of charts in the separate chart to the eye in an identical condition or a non-identical condition, thereby to perform a subjective measurement of the eye.

摘要翻译： 客观折射测量装置包括具有单独布置的一对图表的单独图表，用于通过聚焦透镜将分离图表投影到待检查眼睛的光学系统和具有对应于分离布置的一对通孔的隔膜 的一对图表，用于对眼睛进行聚焦操作的操作单元和用于通过操作单元沿着光轴方向的聚焦操作来移动聚焦透镜的控制单元，以获得该对的投影图像 在相同条件或不相同条件下，将单独图表中的图表与眼睛进行对比，从而进行眼睛的主观测量。

公开(公告)号：US07275584B2

公开(公告)日：2007-10-02

申请号：US10569006

申请日：2004-08-23

申请人： Katsumi Morikawa ,  Joki Yoshitomi ,  Keisuke Asano ,  Saeko Uchida

发明人： Katsumi Morikawa ,  Joki Yoshitomi ,  Keisuke Asano ,  Saeko Uchida

IPC分类号： B22D11/10 ,  B22D41/54

CPC分类号： C04B35/66 ,  B22D41/507 ,  B22D41/54 ,  B22D41/58 ,  C04B35/013 ,  C04B35/06 ,  C04B35/18 ,  C04B2235/3821 ,  C04B2235/3826 ,  C04B2235/402 ,  C04B2235/428 ,  C04B2235/77 ,  C04B2235/94 ,  C04B2235/96 ,  C04B2235/9607 ,  C04B2235/9676

摘要： A nozzle for continuous casting of clean steel is capable of preventing adhesion of Al2O3-based inclusions to a wall surface of the inner hole of the nozzle while fully achieving an effect of a swirl vane. The swirl vane prevents drift in molten steel passing through the inner hole. The swirl vane is disposed in the inner hole. A wall surface is at least partly formed as a tubular-shaped refractory layer and is prepared by controlling a weight ratio of CaO/MgO and an apparent porosity to have a thickness of 3 to 20 mm, so as to prevent adhesion of Al2O3-based inclusions to the wall surface and the swirl vane while effectively maintaining the anti-drift effect for long hours. Further, inert gas is injected into a molten steel flow between an upper nozzle and the swirl vane to facilitate surfacing of Al2O3-based inclusions in a mold and reduce Al2O3-based inclusions in molten steel so as to achieve stable casting operation and high-quality steel with high cleanness.

摘要翻译： 用于连续铸造清洁钢的喷嘴能够防止基于Al 2 N 3 O 3的夹杂物粘附到喷嘴内孔的壁表面，同时完全实现 旋流叶片的作用。 旋流叶片防止了通过内孔的钢水中的漂移。 旋流叶片设置在内孔中。 壁表面至少部分地形成为管状耐火层，并且通过将CaO / MgO的重量比和表观孔隙率控制为具有3至20mm的厚度来制备，以防止Al _{2 3 的夹杂物，同时有效地保持长时间的抗漂移效果。 此外，将惰性气体注入到上喷嘴和旋流叶片之间的钢水流中，以便使模具中的Al 2 N 3 O 3基夹杂物表面化并且还原Al 在钢水中含有2 3 的夹杂物，以实现稳定的铸造操作和高清洁度的优质钢。}

公开(公告)号：US5844661A

公开(公告)日：1998-12-01

申请号：US911977

申请日：1997-08-15

申请人： Saeko Uchida ,  Yasuo Kato ,  Takeshi Nakamura

发明人： Saeko Uchida ,  Yasuo Kato ,  Takeshi Nakamura

IPC分类号： A61B3/103 ,  A61B3/10

CPC分类号： A61B3/103

摘要： An objective refraction measuring system of an ophthalmic apparatus measures a refractive power of an eye to be examined in an objective manner under the condition that a gazing chart of a gazing target system is fixed to the eye to be examined. An arithmetic-logic unit obtains an objective measurement value of the eye to be examined on the basis of the measurement result by the objective refraction measuring system and the gazing target system. A control unit controls a continuous objective measurement while fogging the gazing chart after setting the gazing chart of the gazing chart system to a far-sight position of the eye to be examined which is obtained by using the gazing target system. With such measurement, the continuous objective measurement values by fogging the gazing chart of the gazing target system is obtained from the far-sight position based upon the objective measurement of the eye to be examined. Thus, the limit of the adjustment force of the eye to be examined is precisely measured.

摘要翻译： 眼科装置的客观折射测量系统在目标系统的注视图固定在待检眼上的条件下，以客观的方式测量被检眼的屈光度。 算术逻辑单元基于目标折射测量系统和注视目标系统的测量结果来获得要检查的眼睛的客观测量值。 控制单元控制连续的客观测量，同时在将注视图系统的注视图设置到通过使用注视目标系统获得的被检眼的远视位置之后使注视图发生雾化。 通过这样的测量，基于要检查的眼睛的客观测量，从远景位置获得通过使注视目标系统的注视图发生雾化的连续客观测量值。 因此，精确地测量被检眼的调节力的极限。