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公开(公告)号：US09327220B2
公开(公告)日：2016-05-03
申请号：US14054668
申请日：2013-10-15
CPC分类号： B01D35/02 , B01D15/165 , B01L3/5635 , B01L2200/0684 , B01L2300/046 , B01L2300/0681 , C12M23/08 , C12M23/38 , C12M29/04 , C12M47/10
摘要： A cap has recess containing a porous frit and a graded porosity filter located so fluid from a container to which the cap is connected passes through the filter and out a spout on the cap. The filter porosity is selected to pass product expressed from cellular organisms grown in growth media inside the container while filtering out debris. A cap vent allows positive pressure in the container ullage to expedite filtering and reduce agitation of the container contents. This is not just a cap with a filter but an enabling tool. This tool enables total design change in many processes from previous thinking, allowing for the maximization of purified material, and reduction of multiple steps.
摘要翻译： 帽具有包含多孔玻璃料的凹部和分级孔隙过滤器，其定位成使得与盖相连的容器流体通过过滤器并且在盖上排出喷嘴。 选择过滤器孔隙率以通过在容器内生长培养基中生长的细胞生物体表达的产物，同时滤出碎片。 盖帽通风口允许容器空间中的正压力以加速过滤并减少容器内容物的搅动。 这不仅仅是一个带过滤器的帽子，而是一个启用工具。 该工具可以在以前的想法中进行许多过程中的总体设计更改，从而实现纯化材料的最大化以及减少多个步骤。
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公开(公告)号：US20140170747A1
公开(公告)日：2014-06-19
申请号：US14054668
申请日：2013-10-15
CPC分类号： B01D35/02 , B01D15/165 , B01L3/5635 , B01L2200/0684 , B01L2300/046 , B01L2300/0681 , C12M23/08 , C12M23/38 , C12M29/04 , C12M47/10
摘要： A cap has recess containing a porous frit and a graded porosity filter located so fluid from a container to which the cap is connected passes through the filter and out a spout on the cap. The filter porosity is selected to pass product expressed from cellular organisms grown in growth media inside the container while filtering out debris. A cap vent allows positive pressure in the container ullage to expedite filtering and reduce agitation of the container contents. This is not just a cap with a filter but an enabling tool. This tool enables total design change in many processes from previous thinking, allowing for the maximization of purified material, and reduction of multiple steps.
摘要翻译： 帽具有包含多孔玻璃料的凹部和分级孔隙过滤器，其定位成使得与盖相连的容器流体通过过滤器并且在盖上排出喷嘴。 选择过滤器孔隙率以通过在容器内生长培养基中生长的细胞生物体表达的产物，同时滤出碎片。 盖帽通风口允许容器空间中的正压力以加速过滤并减少容器内容物的搅动。 这不仅仅是一个带过滤器的帽子，而是一个启用工具。 该工具可以在以前的想法中进行许多过程中的总体设计更改，从而实现纯化材料的最大化以及减少多个步骤。
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公开(公告)号：US08580560B1
公开(公告)日：2013-11-12
申请号：US13715666
申请日：2012-12-14
CPC分类号： B01D35/02 , B01D15/165 , B01L3/5635 , B01L2200/0684 , B01L2300/046 , B01L2300/0681 , C12M23/08 , C12M23/38 , C12M29/04 , C12M47/10
摘要： A cap has recess containing a porous frit and a graded porosity filter located so fluid from a container to which the cap is connected passes through the filter and out a spout on the cap. The filter porosity is selected to pass product expressed from cellular organisms grown in growth media inside the container while filtering out debris. A cap vent allows positive pressure in the container ullage to expedite filtering and reduce agitation of the container contents. This is not just a cap with a filter but an enabling tool. This tool enables total design change in many processes from previous thinking, allowing for the maximization of purified material, and reduction of multiple steps.
摘要翻译： 帽具有包含多孔玻璃料的凹部和分级孔隙过滤器，其定位成使得与盖相连的容器流体通过过滤器并且在盖上排出喷嘴。 选择过滤器孔隙率以通过在容器内生长培养基中生长的细胞生物体表达的产物，同时滤出碎片。 盖帽通风口允许容器空间中的正压力以加速过滤并减少容器内容物的搅动。 这不仅仅是一个带过滤器的帽子，而是一个启用工具。 该工具可以在以前的想法中进行许多过程中的总体设计更改，从而实现纯化材料的最大化以及减少多个步骤。
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公开(公告)号：US20130228534A1
公开(公告)日：2013-09-05
申请号：US13670190
申请日：2012-11-06
IPC分类号： B01D33/01
CPC分类号： B01D33/0125 , B01L3/502 , B01L3/5021 , B01L2300/0681 , B01L2300/0832 , B01L2400/0478 , G01N2001/4088 , Y10T436/255
摘要： A filter vial for separating biological and chemical fluids has a cylindrical sidewall with an open top and a closed bottom. A protrusion extends upwards from the middle of the bottom to form an annular recess. A tubular plunger has an open bottom end to which is fastened an annular cup having an outer sidewall sized to fit into and seal against the vial's sidewall. An inner sidewall of the annular cup holds a filter over an opening in the bottom of the plunger and forms a shaped cavity leading to that filter. The annular cup on the plunger fits into the annular recess in the vial to force fluid from the vial through the filter and into the plunger.
摘要翻译： 用于分离生物和化学流体的过滤瓶具有具有开口顶部和封闭底部的圆柱形侧壁。 突起从底部的中部向上延伸以形成环形凹部。 管状柱塞具有敞开的底端，紧固有环形杯，所述环形杯的外侧壁的尺寸被设计成适合并密封在小瓶的侧壁上。 环形杯的内侧壁将过滤器保持在柱塞底部的开口上，并形成通向该过滤器的成形空腔。 柱塞上的环形杯配合到小瓶中的环形凹部中，以迫使来自小瓶的流体通过过滤器并进入柱塞。
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公开(公告)号：US20150076069A1
公开(公告)日：2015-03-19
申请号：US14455738
申请日：2014-08-08
CPC分类号： B01D36/00 , B01D15/10 , B01D33/0183 , B01L3/502 , B01L2300/046 , B01L2300/0681 , B01L2300/0832 , B01L2400/0478
摘要： A filter vial and piston are provided where the vial has a cylindrical wall with a closed bottom and open top and with the hollow, tubular piston therein. The piston has a position stop located and configured to abut a mating position stop on the vial to limit relative movement of the piston and vial. The position stops are located to stop the distal end of the piston away from the bottom of the vial a distance of about 10-30% the height of the vial. That a material to be dissolved in a liquid in the vial and to remove unwanted molecules from the liquid with the piston forcing the liquid through the filter but not squeezing the slurry of material so as to force it into the filter.
摘要翻译： 提供过滤瓶和活塞，其中小瓶具有圆柱形壁，其具有封闭的底部和敞开的顶部，并且其中的中空的管状活塞。 活塞具有位置停止部，其位置并构造成邻接小瓶上的配合位置止挡件以限制活塞和小瓶的相对运动。 位置止动件位于使活塞的远端远离瓶的底部距离为瓶的高度的约10-30％的距离。 这种材料被溶解在小瓶中的液体中，并且通过活塞迫使液体通过过滤器而不是挤压材料的浆料从而从液体中除去不需要的分子，从而迫使其进入过滤器。
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公开(公告)号：USD966460S1
公开(公告)日：2022-10-11
申请号：US29715921
申请日：2019-12-05
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公开(公告)号：US09409165B2
公开(公告)日：2016-08-09
申请号：US14589629
申请日：2015-01-05
IPC分类号： B01D35/00 , B01L3/02 , G01N1/18 , B01D33/00 , B01D25/00 , B01D29/00 , B01L3/00 , B01D33/01 , B23P11/02 , B01D35/30 , B01D21/00 , B01D24/28 , B01D35/22 , B01D24/00 , B01D27/00
CPC分类号： B01L3/502 , A61J1/2086 , B01D33/0125 , B01D33/0183 , B01D35/30 , B01L3/5021 , B01L3/5082 , B01L2200/025 , B01L2200/0689 , B01L2300/0609 , B01L2300/0681 , B01L2300/0832 , B01L2300/123 , B01L2400/0478 , B23P11/02 , Y10T29/49826 , Y10T29/49908 , Y10T29/53 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A filter vial and piston are provided where the vial has a cylindrical wall with a closed bottom and open top and with the hollow, tubular piston therein. The piston has a distal end covered by a cup having a proximal cup seal extending outward to engage the walls of the vial to form a fluid tight seal with the vial during use. The distal end of the piston has a piston flange extending outwardly and located adjacent a recess in the piston so the cup forms a snap fit over the piston flange and extends into the recess. The piston flange causes the cup to bulge sufficiently outward to form a fluid tight seal with the vial during use. A filter is placed in the bottom of the cup and abuts an inwardly extending lip on the cup. The filter is held against the lip by a piston support at the distal end of the piston. A cup support at a distal end of the cup also helps support the filter.
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公开(公告)号：US20150118127A1
公开(公告)日：2015-04-30
申请号：US14589629
申请日：2015-01-05
CPC分类号： B01L3/502 , A61J1/2086 , B01D33/0125 , B01D33/0183 , B01D35/30 , B01L3/5021 , B01L3/5082 , B01L2200/025 , B01L2200/0689 , B01L2300/0609 , B01L2300/0681 , B01L2300/0832 , B01L2300/123 , B01L2400/0478 , B23P11/02 , Y10T29/49826 , Y10T29/49908 , Y10T29/53 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A filter vial and piston are provided where the vial has a cylindrical wall with a closed bottom and open top and with the hollow, tubular piston therein. The piston has a distal end covered by a cup having a proximal cup seal extending outward to engage the walls of the vial to form a fluid tight seal with the vial during use. The distal end of the piston has a piston flange extending outwardly and located adjacent a recess in the piston so the cup forms a snap fit over the piston flange and extends into the recess. The piston flange causes the cup to bulge sufficiently outward to form a fluid tight seal with the vial during use. A filter is placed in the bottom of the cup and abuts an inwardly extending lip on the cup. The filter is held against the lip by a piston support at the distal end of the piston. A cup support at a distal end of the cup also helps support the filter.
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公开(公告)号：US08978896B2
公开(公告)日：2015-03-17
申请号：US14034348
申请日：2013-09-23
CPC分类号： B01D33/0125 , B01L3/502 , B01L3/5021 , B01L2300/0681 , B01L2300/0832 , B01L2400/0478 , G01N2001/4088 , Y10T436/255
摘要： An apparatus filters particles from small volumes of liquid in a tubular vial having an open top and closed bottom with a tubular plunger sliding in the vial to force liquid through a filter at the end of the plunger and into a cavity in the plunger. The filter is held by a cap placed over the end of the plunger. The vial's bottom has an upward extending protrusion mating with a conforming recess in the cap to direct liquid to the protraction and filter as the cap abuts the bottom of the vial. Channels in the bottom help direct liquid flow.
摘要翻译： 一种装置在具有开放顶部和封闭底部的管状小瓶中从小体积的液体中过滤颗粒，其中管状柱塞在小瓶中滑动，以迫使液体通过柱塞端部的过滤器并进入柱塞中的空腔。 过滤器由放置在柱塞端部上方的盖子保持。 小瓶的底部具有向上延伸的突起，其与帽中的适形凹部配合，以在帽与瓶的底部接合时将液体引导至伸出和过滤。 底部通道有助于直接液体流动。
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