公开(公告)号：US08192924B1

公开(公告)日：2012-06-05

申请号：US13274593

申请日：2011-10-17

申请人： Maurice Barakat ,  Louis Thibault ,  Klaus H. Haarmann ,  Annie Beauséjour ,  Anthony Alleva ,  Mario Tremblay ,  Serghe Lapointe

发明人： Maurice Barakat ,  Louis Thibault ,  Klaus H. Haarmann ,  Annie Beauséjour ,  Anthony Alleva ,  Mario Tremblay ,  Serghe Lapointe

IPC分类号： A01D22/00 ,  F28D15/00 ,  B29D22/00 ,  B29D23/00

CPC分类号： B65B3/04 ,  A01N1/0252 ,  A01N1/0284 ,  B29C65/8238 ,  B29C66/1122 ,  B29C66/242 ,  B29C66/43 ,  B29C66/71 ,  B29D22/003 ,  B29L2031/7148 ,  F28D20/02 ,  F28D2020/0008 ,  Y02E60/145 ,  Y10T156/10 ,  Y10T428/13 ,  Y10T428/1352 ,  Y10T428/1393 ,  Y10T428/231 ,  Y10T428/234 ,  Y10T428/239 ,  B29K2023/06

摘要： A new blood unit cooling system was designed to cool blood rapidly to about 22° C. and maintain it at about that temperature, even in ambient temperature extremes, for several hours. The system incorporating a preferred eutectic solution including 98% 1-dodecanol, 1.5% myristyl alcohol and 0.5% 1-decanol (having a melting point of about 23° C.) contained in a sealed flexible polymer layer, was used to cool whole blood-filled bags. The preferred design used double-layered transparent polyethylene, with two sealed compartments filled with the solution, separated by a flattened and sealed portion between them. One of the two sealed compartments contacts one side of the blood bag and the other compartment is folded over to contact the other side of the blood bag. The transparent compartments allows an operator to verify at any time whether the solution is in a solid state, and the flexibility of the compartments eases the proper positioning of them around a blood bag.

摘要翻译： 设计了一种新的血液单元冷却系统，将血液快速冷却至约22°C，并将其保持在该温度即使在环境温度极端，持续数小时。 将包含在密封的柔性聚合物层中的包含98％1-十二烷醇，1.5％十四烷醇和0.5％1-癸醇（熔点约23℃）的优选共晶溶液的系统用于冷却全血 填充袋。 优选的设计是使用双层透明聚乙烯，其中两个密封隔室填充有溶液，它们之间被平坦且密封的部分隔开。 两个密封隔室中的一个接触血袋的一侧，另一个隔室被折叠以接触血袋的另一侧。 透明隔间允许操作者随时验证溶液是否处于固体状态，并且隔室的柔性使其在血袋周围的适当定位变得容易。