公开(公告)号：US08150526B2

公开(公告)日：2012-04-03

申请号：US12368150

申请日：2009-02-09

申请人： Yossi Gross ,  Shai Vaingast

发明人： Yossi Gross ,  Shai Vaingast

IPC分类号： A61N1/36

CPC分类号： A61N1/36046 ,  A61N1/0543 ,  A61N1/37217 ,  A61N1/3787 ,  H01L27/14621 ,  H01L27/14627 ,  H01L31/145

摘要： Apparatus is provided, including an external device, including a mount, which is placed in front of an eye of a subject. A laser is coupled to the mount and configured to emit toward the eye radiation that is outside of 380-750 nm. A partially-transparent mirror is coupled to the mount. An intraocular device is implanted entirely in the subject's eye, and includes a plurality of stimulating electrodes, and an energy receiver, which receives the radiation from the laser and generates a voltage drop in response thereto. A plurality of photosensors detect photons and generate a signal in response thereto. Driving circuitry is coupled to the energy receiver and to the photosensors, and receives the signals from the photosensors and utilizes the voltage drop to drive the electrodes to apply currents to the retina in response to the signals from the photosensors. Other embodiments are also described.

摘要翻译： 提供了一种装置，包括外部装置，其包括安装件，该安装件放置在被检体的眼睛前方。 激光器耦合到安装座并且被配置为朝向在380-750nm之外的眼睛辐射发射。 部分透明的镜子连接到安装座。 眼内装置完全植入受试者的眼睛，并且包括多个刺激电极和能量接收器，其接收来自激光器的辐射并响应于此产生电压降。 多个光电传感器检测光子并响应于此产生信号。 驱动电路耦合到能量接收器和光电传感器，并且接收来自光电传感器的信号，并且利用电压降来驱动电极，以响应于来自光电传感器的信号而向视网膜施加电流。 还描述了其它实施例。

公开(公告)号：US20120035726A1

公开(公告)日：2012-02-09

申请号：US13103264

申请日：2011-05-09

申请人： Yosef Gross ,  Shai Vaingast ,  Ra'anan Gefen

发明人： Yosef Gross ,  Shai Vaingast ,  Ra'anan Gefen

IPC分类号： A61F2/16

CPC分类号： A61N1/36046 ,  A61F2/16 ,  A61F2250/0001 ,  A61N1/0543 ,  A61N1/3787

摘要： Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

摘要翻译： 提供了与外部不可见光源一起使用的装置。 该装置包括配置用于植入人眼中并包括能量接收器的眼内装置。 能量接收器被配置为接收从外部不可见光源发射的光，并且从发射的光提取能量以为眼内装置供电。 眼内装置被配置为基于由外部不可见光源发射并由能量接收器接收的光的调制来调节眼内装置的操作参数。 还描述了其它实施例。

公开(公告)号：US20100204754A1

公开(公告)日：2010-08-12

申请号：US12368150

申请日：2009-02-09

申请人： Yossi Gross ,  Shai Vaingast

发明人： Yossi Gross ,  Shai Vaingast

IPC分类号： A61N1/36

CPC分类号： A61N1/36046 ,  A61N1/0543 ,  A61N1/37217 ,  A61N1/3787 ,  H01L27/14621 ,  H01L27/14627 ,  H01L31/145

摘要： Apparatus is provided, including an external device, including a mount, which is placed in front of an eye of a subject. A laser is coupled to the mount and configured to emit toward the eye radiation that is outside of 380-750 nm. A partially-transparent mirror is coupled to the mount. An intraocular device is implanted entirely in the subject's eye, and includes a plurality of stimulating electrodes, and an energy receiver, which receives the radiation from the laser and generates a voltage drop in response thereto. A plurality of photosensors detect photons and generate a signal in response thereto. Driving circuitry is coupled to the energy receiver and to the photosensors, and receives the signals from the photosensors and utilizes the voltage drop to drive the electrodes to apply currents to the retina in response to the signals from the photosensors. Other embodiments are also described.

摘要翻译： 提供了一种装置，包括外部装置，其包括安装件，该安装件放置在被检体的眼睛前方。 激光器耦合到安装座并且被配置为朝向在380-750nm之外的眼睛辐射发射。 部分透明的镜子连接到安装座。 眼内装置完全植入受试者的眼睛，并且包括多个刺激电极和能量接收器，其接收来自激光器的辐射并响应于此产生电压降。 多个光电传感器检测光子并响应于此产生信号。 驱动电路耦合到能量接收器和光电传感器，并且接收来自光电传感器的信号，并且利用电压降来驱动电极，以响应于来自光电传感器的信号而向视网膜施加电流。 还描述了其它实施例。

公开(公告)号：US20120041514A1

公开(公告)日：2012-02-16

申请号：US13148461

申请日：2010-02-03

申请人： Yossi Gross ,  Shai Vaingast ,  Ra'anan Gefen

发明人： Yossi Gross ,  Shai Vaingast ,  Ra'anan Gefen

IPC分类号： A61F9/08 ,  A61N1/36

CPC分类号： A61N1/36046 ,  A61N1/0543 ,  A61N1/37217 ,  A61N1/3787 ,  H01L27/14621 ,  H01L27/14627 ,  H01L31/145

摘要： An external device (20) includes a mount (22), which is placed in front of a subject's eye. A laser (24) is coupled to the mount (22) and emits radiation (26) that is outside of 380-750 nm. A partially-transparent mirror (23) is coupled to the mount (22). An intraocular device (30) is implanted entirely in the subject's eye, and includes a plurality of stimulating electrodes (38), and an energy receiver (32), which receives the radiation (26) from the laser (24) and generates a voltage drop. A plurality of photosensors (34) detect photons (33) and generate a signal. Driving circuitry (36) is coupled to the energy receiver (32) and to the photosensors (34), and receives the signals from the photosensors (34) and utilizes the voltage drop to drive the electrodes (38) to apply currents to the retina in response to the signals from the photosensors (34). Other embodiments are also described.

摘要翻译： 外部装置（20）包括安装件（22），其安置在被检眼的前方。 激光器（24）耦合到安装件（22）并且发射在380-750nm之外的辐射（26）。 部分透明的反射镜（23）联接到安装件（22）。 将眼内装置（30）完全注入被检者的眼睛，并且包括多个刺激电极（38）和能量接收器（32），其从激光器（24）接收辐射（26）并产生电压 下降。 多个光电传感器（34）检测光子（33）并产生信号。 驱动电路（36）耦合到能量接收器（32）和光电传感器（34），并且接收来自光电传感器（34）的信号并利用电压降来驱动电极（38）以向视网膜施加电流 响应于来自光电传感器（34）的信号。 还描述了其它实施例。

公开(公告)号：US20060265027A1

公开(公告)日：2006-11-23

申请号：US10538521

申请日：2003-12-11

申请人： Shai Vaingast ,  Ehud Cohen

发明人： Shai Vaingast ,  Ehud Cohen

IPC分类号： A61N1/18

CPC分类号： A61N1/36142 ,  A61N1/36521 ,  A61N1/37 ,  A61N1/3716

摘要： A method for measuring impedance of a tissue (20), consisting of charging a capacitor (C15) to a potential, and discharging the capacitor for a discharge period through the tissue. The method further consists of measuring a voltage drop on the capacitor over the discharge period and determining the impedance of the tissue responsive to the potential, the voltage drop, and the discharge period.

摘要翻译： 一种用于测量组织（20）的阻抗的方法，包括将电容器（C 15）充电到电位，并且通过所述组织将电容器放电放电期间。 该方法还包括在放电周期内测量电容器上的电压降，并根据电位，电压降和放电周期确定组织的阻抗。

公开(公告)号：US09265945B2

公开(公告)日：2016-02-23

申请号：US13148461

申请日：2010-02-03

申请人： Yossi Gross ,  Shai Vaingast ,  Ra'anan Gefen

发明人： Yossi Gross ,  Shai Vaingast ,  Ra'anan Gefen

IPC分类号： A61N1/36 ,  A61N1/372 ,  A61N1/378 ,  H01L27/146 ,  H01L31/14 ,  A61N1/05

CPC分类号： A61N1/36046 ,  A61N1/0543 ,  A61N1/37217 ,  A61N1/3787 ,  H01L27/14621 ,  H01L27/14627 ,  H01L31/145

摘要： An external device (20) includes a mount (22), which is placed in front of a subject's eye. A laser (24) is coupled to the mount (22) and emits radiation (26) that is outside of 380-750 nm. A partially-transparent mirror (23) is coupled to the mount (22). An intraocular device (30) is implanted entirely in the subject's eye, and includes a plurality of stimulating electrodes (38), and an energy receiver (32), which receives the radiation (26) from the laser (24) and generates a voltage drop. A plurality of photosensors (34) detect photons (33) and generate a signal. Driving circuitry (36) is coupled to the energy receiver (32) and to the photosensors (34), and receives the signals from the photosensors (34) and utilizes the voltage drop to drive the electrodes (38) to apply currents to the retina in response to the signals from the photosensors (34). Other embodiments are also described.

摘要翻译： 外部装置（20）包括安装件（22），其安置在被检眼的前方。 激光器（24）耦合到安装件（22）并且发射在380-750nm之外的辐射（26）。 部分透明的反射镜（23）联接到安装件（22）。 将眼内装置（30）完全注入被检者的眼睛，并且包括多个刺激电极（38）和能量接收器（32），其从激光器（24）接收辐射（26）并产生电压 下降。 多个光电传感器（34）检测光子（33）并产生信号。 驱动电路（36）耦合到能量接收器（32）和光电传感器（34），并且接收来自光电传感器（34）的信号并利用电压降来驱动电极（38）以向视网膜施加电流 响应于来自光电传感器（34）的信号。 还描述了其它实施例。

公开(公告)号：US08706243B2

公开(公告)日：2014-04-22

申请号：US13437310

申请日：2012-04-02

申请人： Ra'anan Gefen ,  Yossi Gross ,  Tuvia Liran ,  Shai Vaingast

发明人： Ra'anan Gefen ,  Yossi Gross ,  Tuvia Liran ,  Shai Vaingast

IPC分类号： A61N1/05

CPC分类号： A61N1/3787 ,  A61F2/14 ,  A61F2/148 ,  A61F2/1624 ,  A61F2/1659 ,  A61F9/00 ,  A61F9/008 ,  A61N1/0543 ,  A61N1/36046 ,  A61N1/37217

摘要： Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

摘要翻译： 提供了与外部不可见光源一起使用的装置。 该装置包括配置用于植入人眼中并包括能量接收器的眼内装置。 能量接收器被配置为接收从外部不可见光源发射的光，并且从发射的光提取能量以为眼内装置供电。 眼内装置被配置为基于由外部不可见光源发射并由能量接收器接收的光的调制来调节眼内装置的操作参数。 还描述了其它实施例。

公开(公告)号：US08442641B2

公开(公告)日：2013-05-14

申请号：US13103264

申请日：2011-05-09

申请人： Yosef Gross ,  Shai Vaingast ,  Ra'anan Gefen

发明人： Yosef Gross ,  Shai Vaingast ,  Ra'anan Gefen

IPC分类号： A61N1/36032

CPC分类号： A61N1/36046 ,  A61F2/16 ,  A61F2250/0001 ,  A61N1/0543 ,  A61N1/3787

摘要： Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

摘要翻译： 提供了与外部不可见光源一起使用的装置。 该装置包括配置用于植入人眼中并包括能量接收器的眼内装置。 能量接收器被配置为接收从外部不可见光源发射的光，并且从发射的光提取能量以为眼内装置供电。 眼内装置被配置为基于由外部不可见光源发射并由能量接收器接收的光的调制来调节眼内装置的操作参数。 还描述了其它实施例。

公开(公告)号：US08423132B2

公开(公告)日：2013-04-16

申请号：US10538521

申请日：2003-12-11

申请人： Shai Vaingast ,  Ehud Cohen

发明人： Shai Vaingast ,  Ehud Cohen

IPC分类号： A61N1/00

CPC分类号： A61N1/36142 ,  A61N1/36521 ,  A61N1/37 ,  A61N1/3716

摘要： A method for measuring impedance of a tissue (20), consisting of charging a capacitor (C15) to a potential, and discharging the capacitor for a discharge period through the tissue. The method further consists of measuring a voltage drop on the capacitor over the discharge period and determining the impedance of the tissue responsive to the potential, the voltage drop, and the discharge period.

摘要翻译： 一种用于测量组织（20）的阻抗的方法，包括将电容器（C15）充电到电位，并且通过所述组织将电容器放电放电期间。 该方法还包括在放电周期内测量电容器上的电压降，并根据电位，电压降和放电周期确定组织的阻抗。

公开(公告)号：US20120259410A1

公开(公告)日：2012-10-11

申请号：US13437310

申请日：2012-04-02

申请人： Ra'anan Gefen ,  Yossi Gross ,  Tuvia Liran ,  Shai Vaingast

发明人： Ra'anan Gefen ,  Yossi Gross ,  Tuvia Liran ,  Shai Vaingast

IPC分类号： A61F2/16

CPC分类号： A61N1/3787 ,  A61F2/14 ,  A61F2/148 ,  A61F2/1624 ,  A61F2/1659 ,  A61F9/00 ,  A61F9/008 ,  A61N1/0543 ,  A61N1/36046 ,  A61N1/37217

摘要： Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

摘要翻译： 提供了与外部不可见光源一起使用的装置。 该装置包括配置用于植入人眼中并包括能量接收器的眼内装置。 能量接收器被配置为接收从外部不可见光源发射的光，并且从发射的光提取能量以为眼内装置供电。 眼内装置被配置为基于由外部不可见光源发射并由能量接收器接收的光的调制来调节眼内装置的操作参数。 还描述了其它实施例。